ENZYME entry: EC 5.1.1.14
Accepted Name |
Nocardicin-A epimerase.
|
Reaction catalysed |
- Isonocardicin C <=> nocardicin C
- Isonocardicin A <=> nocardicin A
|
Cofactor(s) |
Pyridoxal 5'-phosphate.
|
Comment(s) |
- The enzyme, characterized from the bacterium Nocardia uniformis,
is involved in the biosynthesis of the monolactam antibiotic
nocardicin A.
- It catalyzes the epimerization of the amino group at position 9' from
(S) configuration to (R).
- The enzyme can act on both isonocardicin A and isonocardicin C,
but the in vivo substrate appears to be the latter.
|
Cross-references |
BRENDA | 5.1.1.14 |
EC2PDB | 5.1.1.14 |
ExplorEnz | 5.1.1.14 |
PRIAM enzyme-specific profiles | 5.1.1.14 |
KEGG Ligand Database for Enzyme Nomenclature | 5.1.1.14 |
IUBMB Enzyme Nomenclature | 5.1.1.14 |
IntEnz | 5.1.1.14 |
MEDLINE | Find literature relating to 5.1.1.14 |
MetaCyc | 5.1.1.14 |
Rhea expert-curated reactions | 5.1.1.14 |
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