ENZYME entry: EC 5.1.1.14
| Accepted Name |
|---|
| Nocardicin-A epimerase.
|
| Reaction catalysed |
|---|
- Isonocardicin C <=> nocardicin C
- Isonocardicin A <=> nocardicin A
|
| Cofactor(s) |
|---|
| Pyridoxal 5'-phosphate.
|
| Comment(s) |
|---|
- The enzyme, characterized from the bacterium Nocardia uniformis,
is involved in the biosynthesis of the monolactam antibiotic
nocardicin A.
- It catalyzes the epimerization of the amino group at position 9' from
(S) configuration to (R).
- The enzyme can act on both isonocardicin A and isonocardicin C,
but the in vivo substrate appears to be the latter.
|
| Cross-references |
|---|
| BRENDA | 5.1.1.14 |
| EC2PDB | 5.1.1.14 |
| ExplorEnz | 5.1.1.14 |
| PRIAM enzyme-specific profiles | 5.1.1.14 |
| KEGG Ligand Database for Enzyme Nomenclature | 5.1.1.14 |
| IUBMB Enzyme Nomenclature | 5.1.1.14 |
| IntEnz | 5.1.1.14 |
| MEDLINE | Find literature relating to 5.1.1.14 |
| MetaCyc | 5.1.1.14 |
| Rhea expert-curated reactions | 5.1.1.14 |
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