ENZYME class: 5.-.-.-
Release of 02-Oct-24
5.-.-.-: Isomerases
All UniProtKB/Swiss-Prot entries corresponding to class 5.-.-.-.
The following ENZYME entries belong to class 5.-.-.-:
| 5.1.1.1 | alanine racemase |
| 5.1.1.2 | methionine racemase |
| 5.1.1.3 | glutamate racemase |
| 5.1.1.4 | proline racemase |
| 5.1.1.5 | lysine racemase |
| 5.1.1.6 | threonine racemase |
| 5.1.1.7 | diaminopimelate epimerase |
| 5.1.1.8 | 4-hydroxyproline epimerase |
| 5.1.1.9 | arginine racemase |
| 5.1.1.10 | amino-acid racemase |
| 5.1.1.11 | phenylalanine racemase (ATP-hydrolyzing) |
| 5.1.1.12 | ornithine racemase |
| 5.1.1.13 | aspartate racemase |
| 5.1.1.14 | nocardicin-A epimerase |
| 5.1.1.15 | 2-aminohexano-6-lactam racemase |
| 5.1.1.16 | protein-serine epimerase |
| 5.1.1.17 | isopenicillin-N epimerase |
| 5.1.1.18 | serine racemase |
| 5.1.1.19 | O-ureido-serine racemase |
| 5.1.1.20 | L-Ala-D/L-Glu epimerase |
| 5.1.1.21 | isoleucine 2-epimerase |
| 5.1.1.22 | 4-hydroxyproline betaine 2-epimerase |
| 5.1.1.23 | UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate epimerase |
| 5.1.1.24 | histidine racemase |
| 5.1.1.25 | N-acetyl-D-glutamate racemase |
| 5.1.1.n1 | Transferred entry: 5.1.1.20 |
| 5.1.2.1 | lactate racemase |
| 5.1.2.2 | mandelate racemase |
| 5.1.2.3 | 3-hydroxybutyryl-CoA epimerase |
| 5.1.2.4 | acetoin racemase |
| 5.1.2.5 | tartrate epimerase |
| 5.1.2.6 | isocitrate epimerase |
| 5.1.2.7 | tagaturonate epimerase |
| 5.1.3.1 | ribulose-phosphate 3-epimerase |
| 5.1.3.2 | UDP-glucose 4-epimerase |
| 5.1.3.3 | aldose 1-epimerase |
| 5.1.3.4 | L-ribulose-5-phosphate 4-epimerase |
| 5.1.3.5 | UDP-arabinose 4-epimerase |
| 5.1.3.6 | UDP-glucuronate 4-epimerase |
| 5.1.3.7 | UDP-N-acetylglucosamine 4-epimerase |
| 5.1.3.8 | N-acylglucosamine 2-epimerase |
| 5.1.3.9 | N-acylglucosamine-6-phosphate 2-epimerase |
| 5.1.3.10 | CDP-paratose 2-epimerase |
| 5.1.3.11 | cellobiose epimerase |
| 5.1.3.12 | Deleted entry |
| 5.1.3.13 | dTDP-4-dehydrorhamnose 3,5-epimerase |
| 5.1.3.14 | UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) |
| 5.1.3.15 | glucose-6-phosphate 1-epimerase |
| 5.1.3.16 | UDP-glucosamine 4-epimerase |
| 5.1.3.17 | heparosan-N-sulfate-glucuronate 5-epimerase |
| 5.1.3.18 | GDP-mannose 3,5-epimerase |
| 5.1.3.19 | chondroitin-glucuronate 5-epimerase |
| 5.1.3.20 | ADP-glyceromanno-heptose 6-epimerase |
| 5.1.3.21 | maltose epimerase |
| 5.1.3.22 | L-ribulose-5-phosphate 3-epimerase |
| 5.1.3.23 | UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase |
| 5.1.3.24 | N-acetylneuraminate epimerase |
| 5.1.3.25 | dTDP-L-rhamnose 4-epimerase |
| 5.1.3.26 | N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol |
| 5.1.3.26 | 4-epimerase |
| 5.1.3.27 | dTDP-4-dehydro-6-deoxy-D-glucose 3-epimerase |
| 5.1.3.28 | UDP-N-acetyl-L-fucosamine synthase |
| 5.1.3.29 | L-fucose mutarotase |
| 5.1.3.30 | D-psicose 3-epimerase |
| 5.1.3.31 | D-tagatose 3-epimerase |
| 5.1.3.32 | L-rhamnose mutarotase |
| 5.1.3.33 | 2-epi-5-epi-valiolone epimerase |
| 5.1.3.34 | monoglucosyldiacylglycerol epimerase |
| 5.1.3.35 | 2-epi-5-epi-valiolone 7-phosphate 2-epimerase |
| 5.1.3.36 | heparosan-glucuronate 5-epimerase |
| 5.1.3.37 | mannuronan 5-epimerase |
| 5.1.3.38 | D-erythrulose 1-phosphate 3-epimerase |
| 5.1.3.39 | Deleted entry |
| 5.1.3.40 | D-tagatose 6-phosphate 4-epimerase |
| 5.1.3.41 | fructoselysine 3-epimerase |
| 5.1.3.42 | D-glucosamine-6-phosphate 4-epimerase |
| 5.1.3.43 | sulfoquinovose mutarotase |
| 5.1.3.44 | mannose 2-epimerase |
| 5.1.3.n1 | Transferred entry: 5.1.3.24 |
| 5.1.3.n2 | Transferred entry: 5.1.3.29 |
| 5.1.3.n3 | Transferred entry: 5.1.3.32 |
| 5.1.99.1 | methylmalonyl-CoA epimerase |
| 5.1.99.2 | 16-hydroxysteroid epimerase |
| 5.1.99.3 | allantoin racemase |
| 5.1.99.4 | alpha-methylacyl-CoA racemase |
| 5.1.99.5 | hydantoin racemase |
| 5.1.99.6 | NAD(P)H-hydrate epimerase |
| 5.1.99.7 | dihydroneopterin triphosphate 2'-epimerase |
| 5.1.99.8 | 7,8-dihydroneopterin epimerase |
| 5.2.1.1 | maleate isomerase |
| 5.2.1.2 | maleylacetoacetate isomerase |
| 5.2.1.3 | Deleted entry |
| 5.2.1.4 | maleylpyruvate isomerase |
| 5.2.1.5 | linoleate isomerase |
| 5.2.1.6 | furylfuramide isomerase |
| 5.2.1.7 | Transferred entry: 3.1.1.64 |
| 5.2.1.8 | peptidylprolyl isomerase |
| 5.2.1.9 | farnesol 2-isomerase |
| 5.2.1.10 | 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase |
| 5.2.1.11 | Deleted entry |
| 5.2.1.12 | zeta-carotene isomerase |
| 5.2.1.13 | prolycopene isomerase |
| 5.2.1.14 | beta-carotene isomerase |
| 5.3.1.1 | triose-phosphate isomerase |
| 5.3.1.2 | Deleted entry |
| 5.3.1.3 | D-arabinose isomerase |
| 5.3.1.4 | L-arabinose isomerase |
| 5.3.1.5 | xylose isomerase |
| 5.3.1.6 | ribose-5-phosphate isomerase |
| 5.3.1.7 | mannose isomerase |
| 5.3.1.8 | mannose-6-phosphate isomerase |
| 5.3.1.9 | glucose-6-phosphate isomerase |
| 5.3.1.10 | Transferred entry: 3.5.99.6 |
| 5.3.1.11 | Deleted entry |
| 5.3.1.12 | glucuronate isomerase |
| 5.3.1.13 | arabinose-5-phosphate isomerase |
| 5.3.1.14 | L-rhamnose isomerase |
| 5.3.1.15 | D-lyxose ketol-isomerase |
| 5.3.1.16 | 1-(5-phosphoribosyl)-5- |
| 5.3.1.16 | [(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide |
| 5.3.1.16 | isomerase |
| 5.3.1.17 | 5-dehydro-4-deoxy-D-glucuronate isomerase |
| 5.3.1.18 | Deleted entry |
| 5.3.1.19 | Transferred entry: 2.6.1.16 |
| 5.3.1.20 | ribose isomerase |
| 5.3.1.21 | corticosteroid side-chain-isomerase |
| 5.3.1.22 | hydroxypyruvate isomerase |
| 5.3.1.23 | S-methyl-5-thioribose-1-phosphate isomerase |
| 5.3.1.24 | phosphoribosylanthranilate isomerase |
| 5.3.1.25 | L-fucose isomerase |
| 5.3.1.26 | galactose-6-phosphate isomerase |
| 5.3.1.27 | 6-phospho-3-hexuloisomerase |
| 5.3.1.28 | D-sedoheptulose-7-phosphate isomerase |
| 5.3.1.29 | ribose-1,5-bisphosphate isomerase |
| 5.3.1.30 | 5-deoxy-glucuronate isomerase |
| 5.3.1.31 | sulfoquinovose isomerase |
| 5.3.1.32 | (4S)-4-hydroxy-5-phosphooxypentane-2,3-dione isomerase |
| 5.3.1.33 | L-erythrulose-1-phosphate isomerase |
| 5.3.1.34 | D-erythrulose 4-phosphate isomerase |
| 5.3.1.35 | 2-dehydrotetronate isomerase |
| 5.3.1.36 | D-apiose isomerase |
| 5.3.1.37 | 4-deoxy-4-sulfo-D-erythrose isomerase |
| 5.3.1.n1 | Transferred entry: 5.3.1.30 |
| 5.3.1.n2 | Transferred entry: 5.3.1.29 |
| 5.3.2.1 | phenylpyruvate tautomerase |
| 5.3.2.2 | oxaloacetate tautomerase |
| 5.3.2.3 | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6- |
| 5.3.2.3 | deoxy-alpha-D-galactopyranose-forming) |
| 5.3.2.4 | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6- |
| 5.3.2.4 | deoxy-alpha-D-glucopyranose-forming) |
| 5.3.2.5 | 2,3-diketo-5-methylthiopentyl-1-phosphate enolase |
| 5.3.2.6 | 2-hydroxymuconate tautomerase |
| 5.3.2.7 | ascopyrone tautomerase |
| 5.3.2.8 | 4-oxalomesaconate tautomerase |
| 5.3.2.n1 | Transferred entry: 5.3.2.5 |
| 5.3.3.1 | steroid Delta-isomerase |
| 5.3.3.2 | isopentenyl-diphosphate Delta-isomerase |
| 5.3.3.3 | vinylacetyl-CoA Delta-isomerase |
| 5.3.3.4 | muconolactone Delta-isomerase |
| 5.3.3.5 | cholestenol Delta-isomerase |
| 5.3.3.6 | methylitaconate Delta-isomerase |
| 5.3.3.7 | aconitate Delta-isomerase |
| 5.3.3.8 | Delta(3)-Delta(2)-enoyl-CoA isomerase |
| 5.3.3.9 | prostaglandin-A1 Delta-isomerase |
| 5.3.3.10 | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase |
| 5.3.3.11 | isopiperitenone Delta-isomerase |
| 5.3.3.12 | L-dopachrome isomerase |
| 5.3.3.13 | polyenoic fatty acid isomerase |
| 5.3.3.14 | trans-2-decenoyl-[acyl-carrier-protein] isomerase |
| 5.3.3.15 | Transferred entry: 5.3.2.7 |
| 5.3.3.16 | Transferred entry: 5.3.2.8 |
| 5.3.3.17 | trans-2,3-dihydro-3-hydroxyanthranilate isomerase |
| 5.3.3.18 | 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase |
| 5.3.3.19 | 3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate isomerase |
| 5.3.3.20 | Transferred entry: 5.4.99.64 |
| 5.3.3.21 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase |
| 5.3.3.22 | lutein isomerase |
| 5.3.3.23 | S-methyl-5-thioribulose 1-phosphate isomerase |
| 5.3.3.24 | neopinone isomerase |
| 5.3.4.1 | protein disulfide-isomerase |
| 5.3.99.1 | Deleted entry |
| 5.3.99.2 | prostaglandin-D synthase |
| 5.3.99.3 | prostaglandin-E synthase |
| 5.3.99.4 | prostaglandin-I synthase |
| 5.3.99.5 | thromboxane-A synthase |
| 5.3.99.6 | allene-oxide cyclase |
| 5.3.99.7 | styrene-oxide isomerase |
| 5.3.99.8 | capsanthin/capsorubin synthase |
| 5.3.99.9 | neoxanthin synthase |
| 5.3.99.10 | thiazole tautomerase |
| 5.3.99.11 | 2-keto-myo-inositol isomerase |
| 5.3.99.12 | lachrymatory-factor synthase |
| 5.3.99.n1 | Transferred entry: 5.3.99.11 |
| 5.4.1.1 | lysolecithin acylmutase |
| 5.4.1.2 | Transferred entry: 5.4.99.61 |
| 5.4.1.3 | 2-methylfumaryl-CoA isomerase |
| 5.4.1.4 | D-galactarolactone isomerase |
| 5.4.2.1 | Transferred entry: 5.4.2.11 and 5.4.2.12 |
| 5.4.2.2 | phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) |
| 5.4.2.3 | phosphoacetylglucosamine mutase |
| 5.4.2.4 | bisphosphoglycerate mutase |
| 5.4.2.5 | phosphoglucomutase (glucose-cofactor) |
| 5.4.2.6 | beta-phosphoglucomutase |
| 5.4.2.7 | phosphopentomutase |
| 5.4.2.8 | phosphomannomutase |
| 5.4.2.9 | phosphoenolpyruvate mutase |
| 5.4.2.10 | phosphoglucosamine mutase |
| 5.4.2.11 | phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) |
| 5.4.2.12 | phosphoglycerate mutase (2,3-diphosphoglycerate-independent) |
| 5.4.2.13 | phosphogalactosamine mutase |
| 5.4.3.1 | Deleted entry |
| 5.4.3.2 | lysine 2,3-aminomutase |
| 5.4.3.3 | lysine 5,6-aminomutase |
| 5.4.3.4 | Transferred entry: 5.4.3.3 |
| 5.4.3.5 | D-ornithine 4,5-aminomutase |
| 5.4.3.6 | tyrosine 2,3-aminomutase |
| 5.4.3.7 | leucine 2,3-aminomutase |
| 5.4.3.8 | glutamate-1-semialdehyde 2,1-aminomutase |
| 5.4.3.9 | glutamate 2,3-aminomutase |
| 5.4.3.10 | phenylalanine aminomutase (L-beta-phenylalanine forming) |
| 5.4.3.11 | phenylalanine aminomutase (D-beta-phenylalanine forming) |
| 5.4.4.1 | (hydroxyamino)benzene mutase |
| 5.4.4.2 | isochorismate synthase |
| 5.4.4.3 | 3-(hydroxyamino)phenol mutase |
| 5.4.4.4 | geraniol isomerase |
| 5.4.4.5 | 9,12-octadecadienoate 8-hydroperoxide 8R-isomerase |
| 5.4.4.6 | 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase |
| 5.4.4.7 | hydroperoxy icosatetraenoate isomerase |
| 5.4.4.8 | linalool isomerase |
| 5.4.99.1 | methylaspartate mutase |
| 5.4.99.2 | methylmalonyl-CoA mutase |
| 5.4.99.3 | 2-acetolactate mutase |
| 5.4.99.4 | 2-methyleneglutarate mutase |
| 5.4.99.5 | chorismate mutase |
| 5.4.99.6 | Transferred entry: 5.4.4.2 |
| 5.4.99.7 | lanosterol synthase |
| 5.4.99.8 | cycloartenol synthase |
| 5.4.99.9 | UDP-galactopyranose mutase |
| 5.4.99.10 | Transferred entry: 5.4.99.11 |
| 5.4.99.11 | isomaltulose synthase |
| 5.4.99.12 | tRNA pseudouridine(38-40) synthase |
| 5.4.99.13 | isobutyryl-CoA mutase |
| 5.4.99.14 | 4-carboxymethyl-4-methylbutenolide mutase |
| 5.4.99.15 | (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase |
| 5.4.99.16 | maltose alpha-D-glucosyltransferase |
| 5.4.99.17 | squalene--hopene cyclase |
| 5.4.99.18 | 5-(carboxyamino)imidazole ribonucleotide mutase |
| 5.4.99.19 | 16S rRNA pseudouridine(516) synthase |
| 5.4.99.20 | 23S rRNA pseudouridine(2457) synthase |
| 5.4.99.21 | 23S rRNA pseudouridine(2604) synthase |
| 5.4.99.22 | 23S rRNA pseudouridine(2605) synthase |
| 5.4.99.23 | 23S rRNA pseudouridine(1911/1915/1917) synthase |
| 5.4.99.24 | 23S rRNA pseudouridine(955/2504/2580) synthase |
| 5.4.99.25 | tRNA pseudouridine(55) synthase |
| 5.4.99.26 | tRNA pseudouridine(65) synthase |
| 5.4.99.27 | tRNA pseudouridine(13) synthase |
| 5.4.99.28 | tRNA pseudouridine(32) synthase |
| 5.4.99.29 | 23S rRNA pseudouridine(746) synthase |
| 5.4.99.30 | UDP-arabinopyranose mutase |
| 5.4.99.31 | thalianol synthase |
| 5.4.99.32 | protostadienol synthase |
| 5.4.99.33 | cucurbitadienol synthase |
| 5.4.99.34 | germanicol synthase |
| 5.4.99.35 | taraxerol synthase |
| 5.4.99.36 | isomultiflorenol synthase |
| 5.4.99.37 | dammaradiene synthase |
| 5.4.99.38 | camelliol C synthase |
| 5.4.99.39 | beta-amyrin synthase |
| 5.4.99.40 | alpha-amyrin synthase |
| 5.4.99.41 | lupeol synthase |
| 5.4.99.42 | tRNA pseudouridine(31) synthase |
| 5.4.99.43 | 21S rRNA pseudouridine(2819) synthase |
| 5.4.99.44 | mitochondrial tRNA pseudouridine(27/28) synthase |
| 5.4.99.45 | tRNA pseudouridine(38/39) synthase |
| 5.4.99.46 | shionone synthase |
| 5.4.99.47 | parkeol synthase |
| 5.4.99.48 | achilleol B synthase |
| 5.4.99.49 | glutinol synthase |
| 5.4.99.50 | friedelin synthase |
| 5.4.99.51 | baccharis oxide synthase |
| 5.4.99.52 | alpha-seco-amyrin synthase |
| 5.4.99.53 | marneral synthase |
| 5.4.99.54 | beta-seco-amyrin synthase |
| 5.4.99.55 | delta-amyrin synthase |
| 5.4.99.56 | tirucalladienol synthase |
| 5.4.99.57 | baruol synthase |
| 5.4.99.58 | methylornithine synthase |
| 5.4.99.59 | dTDP-fucopyranose mutase |
| 5.4.99.60 | cobalt-precorrin-8 methylmutase |
| 5.4.99.61 | precorrin-8X methylmutase |
| 5.4.99.62 | D-ribose pyranase |
| 5.4.99.63 | ethylmalonyl-CoA mutase |
| 5.4.99.64 | 2-hydroxyisobutanoyl-CoA mutase |
| 5.4.99.65 | pre-alpha-onocerin synthase |
| 5.4.99.66 | alpha-onocerin synthase |
| 5.4.99.67 | 4-amino-4-deoxychorismate mutase |
| 5.4.99.n1 | Transferred entry: 5.4.99.39 |
| 5.4.99.n2 | Transferred entry: 5.4.99.41 |
| 5.5.1.1 | muconate cycloisomerase |
| 5.5.1.2 | 3-carboxy-cis,cis-muconate cycloisomerase |
| 5.5.1.3 | tetrahydroxypteridine cycloisomerase |
| 5.5.1.4 | inositol-3-phosphate synthase |
| 5.5.1.5 | carboxy-cis,cis-muconate cyclase |
| 5.5.1.6 | chalcone isomerase |
| 5.5.1.7 | chloromuconate cycloisomerase |
| 5.5.1.8 | (+)-bornyl diphosphate synthase |
| 5.5.1.9 | cycloeucalenol cycloisomerase |
| 5.5.1.10 | alpha-pinene-oxide decyclase |
| 5.5.1.11 | dichloromuconate cycloisomerase |
| 5.5.1.12 | copalyl diphosphate synthase |
| 5.5.1.13 | ent-copalyl diphosphate synthase |
| 5.5.1.14 | syn-copalyl-diphosphate synthase |
| 5.5.1.15 | terpentedienyl-diphosphate synthase |
| 5.5.1.16 | halimadienyl-diphosphate synthase |
| 5.5.1.17 | (S)-beta-macrocarpene synthase |
| 5.5.1.18 | lycopene epsilon-cyclase |
| 5.5.1.19 | lycopene beta-cyclase |
| 5.5.1.20 | prosolanapyrone-III cycloisomerase |
| 5.5.1.21 | Transferred entry: 4.2.1.133 |
| 5.5.1.22 | (-)-bornyl diphosphate synthase |
| 5.5.1.23 | aklanonic acid methyl ester cyclase |
| 5.5.1.24 | tocopherol cyclase |
| 5.5.1.25 | 3,6-anhydro-L-galactonate cycloisomerase |
| 5.5.1.26 | nogalonic acid methyl ester cyclase |
| 5.5.1.27 | D-galactarolactone cycloisomerase |
| 5.5.1.28 | (-)-kolavenyl diphosphate synthase |
| 5.5.1.29 | (+)-kolavenyl diphosphate synthase |
| 5.5.1.30 | labda-7,13-dienyl diphosphate synthase |
| 5.5.1.31 | hapalindole H synthase |
| 5.5.1.32 | 12-epi-hapalindole U synthase |
| 5.5.1.33 | 12-epi-fischerindole U synthase |
| 5.5.1.34 | (+)-cis,trans-nepetalactol synthase |
| 5.5.1.35 | (+)-cis,cis-nepetalactol synthase |
| 5.5.1.36 | hapalindole U synthase |
| 5.5.1.n1 | Transferred entry: 5.4.99.62 |
| 5.5.1.n2 | Transferred entry: 5.5.1.19 |
| 5.6.1.1 | microtubule-severing ATPase |
| 5.6.1.2 | dynein ATPase |
| 5.6.1.3 | plus-end-directed kinesin ATPase |
| 5.6.1.4 | minus-end-directed kinesin ATPase |
| 5.6.1.5 | proteasome ATPase |
| 5.6.1.6 | channel-conductance-controlling ATPase |
| 5.6.1.7 | chaperonin ATPase |
| 5.6.1.8 | myosin ATPase |
| 5.6.1.9 | (R)-2-hydroxyacyl-CoA dehydratase activating ATPase |
| 5.6.2.1 | DNA topoisomerase |
| 5.6.2.2 | DNA topoisomerase (ATP-hydrolyzing) |
| 5.6.2.3 | DNA 5'-3' helicase |
| 5.6.2.4 | DNA 3'-5' helicase |
| 5.6.2.5 | RNA 5'-3' helicase |
| 5.6.2.6 | RNA 3'-5' helicase |
| 5.6.2.7 | DEAD-box RNA helicase |
| 5.99.1.1 | thiocyanate isomerase |
| 5.99.1.2 | Transferred entry: 5.6.2.1 |
| 5.99.1.3 | Transferred entry: 5.6.2.2 |
| 5.99.1.4 | 2-hydroxychromene-2-carboxylate isomerase |