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ENZYME

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ENZYME class: 5.-.-.-


Release of 29-May-24

5.-.-.-: Isomerases

All UniProtKB/Swiss-Prot entries corresponding to class 5.-.-.-.

The following ENZYME entries belong to class 5.-.-.-:

5.1.1.1alanine racemase
5.1.1.2methionine racemase
5.1.1.3glutamate racemase
5.1.1.4proline racemase
5.1.1.5lysine racemase
5.1.1.6threonine racemase
5.1.1.7diaminopimelate epimerase
5.1.1.84-hydroxyproline epimerase
5.1.1.9arginine racemase
5.1.1.10amino-acid racemase
5.1.1.11phenylalanine racemase (ATP-hydrolyzing)
5.1.1.12ornithine racemase
5.1.1.13aspartate racemase
5.1.1.14nocardicin-A epimerase
5.1.1.152-aminohexano-6-lactam racemase
5.1.1.16protein-serine epimerase
5.1.1.17isopenicillin-N epimerase
5.1.1.18serine racemase
5.1.1.19O-ureido-serine racemase
5.1.1.20L-Ala-D/L-Glu epimerase
5.1.1.21isoleucine 2-epimerase
5.1.1.224-hydroxyproline betaine 2-epimerase
5.1.1.23UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate epimerase
5.1.1.24histidine racemase
5.1.1.25N-acetyl-D-glutamate racemase
5.1.1.n1Transferred entry: 5.1.1.20
5.1.2.1lactate racemase
5.1.2.2mandelate racemase
5.1.2.33-hydroxybutyryl-CoA epimerase
5.1.2.4acetoin racemase
5.1.2.5tartrate epimerase
5.1.2.6isocitrate epimerase
5.1.2.7tagaturonate epimerase
5.1.3.1ribulose-phosphate 3-epimerase
5.1.3.2UDP-glucose 4-epimerase
5.1.3.3aldose 1-epimerase
5.1.3.4L-ribulose-5-phosphate 4-epimerase
5.1.3.5UDP-arabinose 4-epimerase
5.1.3.6UDP-glucuronate 4-epimerase
5.1.3.7UDP-N-acetylglucosamine 4-epimerase
5.1.3.8N-acylglucosamine 2-epimerase
5.1.3.9N-acylglucosamine-6-phosphate 2-epimerase
5.1.3.10CDP-paratose 2-epimerase
5.1.3.11cellobiose epimerase
5.1.3.12Deleted entry
5.1.3.13dTDP-4-dehydrorhamnose 3,5-epimerase
5.1.3.14UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
5.1.3.15glucose-6-phosphate 1-epimerase
5.1.3.16UDP-glucosamine 4-epimerase
5.1.3.17heparosan-N-sulfate-glucuronate 5-epimerase
5.1.3.18GDP-mannose 3,5-epimerase
5.1.3.19chondroitin-glucuronate 5-epimerase
5.1.3.20ADP-glyceromanno-heptose 6-epimerase
5.1.3.21maltose epimerase
5.1.3.22L-ribulose-5-phosphate 3-epimerase
5.1.3.23UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase
5.1.3.24N-acetylneuraminate epimerase
5.1.3.25dTDP-L-rhamnose 4-epimerase
5.1.3.26N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
5.1.3.264-epimerase
5.1.3.27dTDP-4-dehydro-6-deoxy-D-glucose 3-epimerase
5.1.3.28UDP-N-acetyl-L-fucosamine synthase
5.1.3.29L-fucose mutarotase
5.1.3.30D-psicose 3-epimerase
5.1.3.31D-tagatose 3-epimerase
5.1.3.32L-rhamnose mutarotase
5.1.3.332-epi-5-epi-valiolone epimerase
5.1.3.34monoglucosyldiacylglycerol epimerase
5.1.3.352-epi-5-epi-valiolone 7-phosphate 2-epimerase
5.1.3.36heparosan-glucuronate 5-epimerase
5.1.3.37mannuronan 5-epimerase
5.1.3.38D-erythrulose 1-phosphate 3-epimerase
5.1.3.39Deleted entry
5.1.3.40D-tagatose 6-phosphate 4-epimerase
5.1.3.41fructoselysine 3-epimerase
5.1.3.42D-glucosamine-6-phosphate 4-epimerase
5.1.3.43sulfoquinovose mutarotase
5.1.3.44mannose 2-epimerase
5.1.3.n1Transferred entry: 5.1.3.24
5.1.3.n2Transferred entry: 5.1.3.29
5.1.3.n3Transferred entry: 5.1.3.32
5.1.99.1methylmalonyl-CoA epimerase
5.1.99.216-hydroxysteroid epimerase
5.1.99.3allantoin racemase
5.1.99.4alpha-methylacyl-CoA racemase
5.1.99.5hydantoin racemase
5.1.99.6NAD(P)H-hydrate epimerase
5.1.99.7dihydroneopterin triphosphate 2'-epimerase
5.1.99.87,8-dihydroneopterin epimerase
5.2.1.1maleate isomerase
5.2.1.2maleylacetoacetate isomerase
5.2.1.3Deleted entry
5.2.1.4maleylpyruvate isomerase
5.2.1.5linoleate isomerase
5.2.1.6furylfuramide isomerase
5.2.1.7Transferred entry: 3.1.1.64
5.2.1.8peptidylprolyl isomerase
5.2.1.9farnesol 2-isomerase
5.2.1.102-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase
5.2.1.11Deleted entry
5.2.1.12zeta-carotene isomerase
5.2.1.13prolycopene isomerase
5.2.1.14beta-carotene isomerase
5.3.1.1triose-phosphate isomerase
5.3.1.2Deleted entry
5.3.1.3D-arabinose isomerase
5.3.1.4L-arabinose isomerase
5.3.1.5xylose isomerase
5.3.1.6ribose-5-phosphate isomerase
5.3.1.7mannose isomerase
5.3.1.8mannose-6-phosphate isomerase
5.3.1.9glucose-6-phosphate isomerase
5.3.1.10Transferred entry: 3.5.99.6
5.3.1.11Deleted entry
5.3.1.12glucuronate isomerase
5.3.1.13arabinose-5-phosphate isomerase
5.3.1.14L-rhamnose isomerase
5.3.1.15D-lyxose ketol-isomerase
5.3.1.161-(5-phosphoribosyl)-5-
5.3.1.16[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide
5.3.1.16isomerase
5.3.1.175-dehydro-4-deoxy-D-glucuronate isomerase
5.3.1.18Deleted entry
5.3.1.19Transferred entry: 2.6.1.16
5.3.1.20ribose isomerase
5.3.1.21corticosteroid side-chain-isomerase
5.3.1.22hydroxypyruvate isomerase
5.3.1.23S-methyl-5-thioribose-1-phosphate isomerase
5.3.1.24phosphoribosylanthranilate isomerase
5.3.1.25L-fucose isomerase
5.3.1.26galactose-6-phosphate isomerase
5.3.1.276-phospho-3-hexuloisomerase
5.3.1.28D-sedoheptulose-7-phosphate isomerase
5.3.1.29ribose-1,5-bisphosphate isomerase
5.3.1.305-deoxy-glucuronate isomerase
5.3.1.31sulfoquinovose isomerase
5.3.1.32(4S)-4-hydroxy-5-phosphooxypentane-2,3-dione isomerase
5.3.1.33L-erythrulose-1-phosphate isomerase
5.3.1.34D-erythrulose 4-phosphate isomerase
5.3.1.352-dehydrotetronate isomerase
5.3.1.36D-apiose isomerase
5.3.1.374-deoxy-4-sulfo-D-erythrose isomerase
5.3.1.n1Transferred entry: 5.3.1.30
5.3.1.n2Transferred entry: 5.3.1.29
5.3.2.1phenylpyruvate tautomerase
5.3.2.2oxaloacetate tautomerase
5.3.2.3TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-
5.3.2.3deoxy-alpha-D-galactopyranose-forming)
5.3.2.4TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-
5.3.2.4deoxy-alpha-D-glucopyranose-forming)
5.3.2.52,3-diketo-5-methylthiopentyl-1-phosphate enolase
5.3.2.62-hydroxymuconate tautomerase
5.3.2.7ascopyrone tautomerase
5.3.2.84-oxalomesaconate tautomerase
5.3.2.n1Transferred entry: 5.3.2.5
5.3.3.1steroid Delta-isomerase
5.3.3.2isopentenyl-diphosphate Delta-isomerase
5.3.3.3vinylacetyl-CoA Delta-isomerase
5.3.3.4muconolactone Delta-isomerase
5.3.3.5cholestenol Delta-isomerase
5.3.3.6methylitaconate Delta-isomerase
5.3.3.7aconitate Delta-isomerase
5.3.3.8Delta(3)-Delta(2)-enoyl-CoA isomerase
5.3.3.9prostaglandin-A1 Delta-isomerase
5.3.3.105-carboxymethyl-2-hydroxymuconate Delta-isomerase
5.3.3.11isopiperitenone Delta-isomerase
5.3.3.12L-dopachrome isomerase
5.3.3.13polyenoic fatty acid isomerase
5.3.3.14trans-2-decenoyl-[acyl-carrier-protein] isomerase
5.3.3.15Transferred entry: 5.3.2.7
5.3.3.16Transferred entry: 5.3.2.8
5.3.3.17trans-2,3-dihydro-3-hydroxyanthranilate isomerase
5.3.3.182-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase
5.3.3.193-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate isomerase
5.3.3.20Transferred entry: 5.4.99.64
5.3.3.21Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase
5.3.3.22lutein isomerase
5.3.3.23S-methyl-5-thioribulose 1-phosphate isomerase
5.3.3.24neopinone isomerase
5.3.4.1protein disulfide-isomerase
5.3.99.1Deleted entry
5.3.99.2prostaglandin-D synthase
5.3.99.3prostaglandin-E synthase
5.3.99.4prostaglandin-I synthase
5.3.99.5thromboxane-A synthase
5.3.99.6allene-oxide cyclase
5.3.99.7styrene-oxide isomerase
5.3.99.8capsanthin/capsorubin synthase
5.3.99.9neoxanthin synthase
5.3.99.10thiazole tautomerase
5.3.99.112-keto-myo-inositol isomerase
5.3.99.12lachrymatory-factor synthase
5.3.99.n1Transferred entry: 5.3.99.11
5.4.1.1lysolecithin acylmutase
5.4.1.2Transferred entry: 5.4.99.61
5.4.1.32-methylfumaryl-CoA isomerase
5.4.1.4D-galactarolactone isomerase
5.4.2.1Transferred entry: 5.4.2.11 and 5.4.2.12
5.4.2.2phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
5.4.2.3phosphoacetylglucosamine mutase
5.4.2.4bisphosphoglycerate mutase
5.4.2.5phosphoglucomutase (glucose-cofactor)
5.4.2.6beta-phosphoglucomutase
5.4.2.7phosphopentomutase
5.4.2.8phosphomannomutase
5.4.2.9phosphoenolpyruvate mutase
5.4.2.10phosphoglucosamine mutase
5.4.2.11phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)
5.4.2.12phosphoglycerate mutase (2,3-diphosphoglycerate-independent)
5.4.2.13phosphogalactosamine mutase
5.4.3.1Deleted entry
5.4.3.2lysine 2,3-aminomutase
5.4.3.3lysine 5,6-aminomutase
5.4.3.4Transferred entry: 5.4.3.3
5.4.3.5D-ornithine 4,5-aminomutase
5.4.3.6tyrosine 2,3-aminomutase
5.4.3.7leucine 2,3-aminomutase
5.4.3.8glutamate-1-semialdehyde 2,1-aminomutase
5.4.3.9glutamate 2,3-aminomutase
5.4.3.10phenylalanine aminomutase (L-beta-phenylalanine forming)
5.4.3.11phenylalanine aminomutase (D-beta-phenylalanine forming)
5.4.4.1(hydroxyamino)benzene mutase
5.4.4.2isochorismate synthase
5.4.4.33-(hydroxyamino)phenol mutase
5.4.4.4geraniol isomerase
5.4.4.59,12-octadecadienoate 8-hydroperoxide 8R-isomerase
5.4.4.69,12-octadecadienoate 8-hydroperoxide 8S-isomerase
5.4.4.7hydroperoxy icosatetraenoate isomerase
5.4.4.8linalool isomerase
5.4.99.1methylaspartate mutase
5.4.99.2methylmalonyl-CoA mutase
5.4.99.32-acetolactate mutase
5.4.99.42-methyleneglutarate mutase
5.4.99.5chorismate mutase
5.4.99.6Transferred entry: 5.4.4.2
5.4.99.7lanosterol synthase
5.4.99.8cycloartenol synthase
5.4.99.9UDP-galactopyranose mutase
5.4.99.10Transferred entry: 5.4.99.11
5.4.99.11isomaltulose synthase
5.4.99.12tRNA pseudouridine(38-40) synthase
5.4.99.13isobutyryl-CoA mutase
5.4.99.144-carboxymethyl-4-methylbutenolide mutase
5.4.99.15(1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase
5.4.99.16maltose alpha-D-glucosyltransferase
5.4.99.17squalene--hopene cyclase
5.4.99.185-(carboxyamino)imidazole ribonucleotide mutase
5.4.99.1916S rRNA pseudouridine(516) synthase
5.4.99.2023S rRNA pseudouridine(2457) synthase
5.4.99.2123S rRNA pseudouridine(2604) synthase
5.4.99.2223S rRNA pseudouridine(2605) synthase
5.4.99.2323S rRNA pseudouridine(1911/1915/1917) synthase
5.4.99.2423S rRNA pseudouridine(955/2504/2580) synthase
5.4.99.25tRNA pseudouridine(55) synthase
5.4.99.26tRNA pseudouridine(65) synthase
5.4.99.27tRNA pseudouridine(13) synthase
5.4.99.28tRNA pseudouridine(32) synthase
5.4.99.2923S rRNA pseudouridine(746) synthase
5.4.99.30UDP-arabinopyranose mutase
5.4.99.31thalianol synthase
5.4.99.32protostadienol synthase
5.4.99.33cucurbitadienol synthase
5.4.99.34germanicol synthase
5.4.99.35taraxerol synthase
5.4.99.36isomultiflorenol synthase
5.4.99.37dammaradiene synthase
5.4.99.38camelliol C synthase
5.4.99.39beta-amyrin synthase
5.4.99.40alpha-amyrin synthase
5.4.99.41lupeol synthase
5.4.99.42tRNA pseudouridine(31) synthase
5.4.99.4321S rRNA pseudouridine(2819) synthase
5.4.99.44mitochondrial tRNA pseudouridine(27/28) synthase
5.4.99.45tRNA pseudouridine(38/39) synthase
5.4.99.46shionone synthase
5.4.99.47parkeol synthase
5.4.99.48achilleol B synthase
5.4.99.49glutinol synthase
5.4.99.50friedelin synthase
5.4.99.51baccharis oxide synthase
5.4.99.52alpha-seco-amyrin synthase
5.4.99.53marneral synthase
5.4.99.54beta-seco-amyrin synthase
5.4.99.55delta-amyrin synthase
5.4.99.56tirucalladienol synthase
5.4.99.57baruol synthase
5.4.99.58methylornithine synthase
5.4.99.59dTDP-fucopyranose mutase
5.4.99.60cobalt-precorrin-8 methylmutase
5.4.99.61precorrin-8X methylmutase
5.4.99.62D-ribose pyranase
5.4.99.63ethylmalonyl-CoA mutase
5.4.99.642-hydroxyisobutanoyl-CoA mutase
5.4.99.65pre-alpha-onocerin synthase
5.4.99.66alpha-onocerin synthase
5.4.99.674-amino-4-deoxychorismate mutase
5.4.99.n1Transferred entry: 5.4.99.39
5.4.99.n2Transferred entry: 5.4.99.41
5.5.1.1muconate cycloisomerase
5.5.1.23-carboxy-cis,cis-muconate cycloisomerase
5.5.1.3tetrahydroxypteridine cycloisomerase
5.5.1.4inositol-3-phosphate synthase
5.5.1.5carboxy-cis,cis-muconate cyclase
5.5.1.6chalcone isomerase
5.5.1.7chloromuconate cycloisomerase
5.5.1.8(+)-bornyl diphosphate synthase
5.5.1.9cycloeucalenol cycloisomerase
5.5.1.10alpha-pinene-oxide decyclase
5.5.1.11dichloromuconate cycloisomerase
5.5.1.12copalyl diphosphate synthase
5.5.1.13ent-copalyl diphosphate synthase
5.5.1.14syn-copalyl-diphosphate synthase
5.5.1.15terpentedienyl-diphosphate synthase
5.5.1.16halimadienyl-diphosphate synthase
5.5.1.17(S)-beta-macrocarpene synthase
5.5.1.18lycopene epsilon-cyclase
5.5.1.19lycopene beta-cyclase
5.5.1.20prosolanapyrone-III cycloisomerase
5.5.1.21Transferred entry: 4.2.1.133
5.5.1.22(-)-bornyl diphosphate synthase
5.5.1.23aklanonic acid methyl ester cyclase
5.5.1.24tocopherol cyclase
5.5.1.253,6-anhydro-L-galactonate cycloisomerase
5.5.1.26nogalonic acid methyl ester cyclase
5.5.1.27D-galactarolactone cycloisomerase
5.5.1.28(-)-kolavenyl diphosphate synthase
5.5.1.29(+)-kolavenyl diphosphate synthase
5.5.1.30labda-7,13-dienyl diphosphate synthase
5.5.1.31hapalindole H synthase
5.5.1.3212-epi-hapalindole U synthase
5.5.1.3312-epi-fischerindole U synthase
5.5.1.34(+)-cis,trans-nepetalactol synthase
5.5.1.35(+)-cis,cis-nepetalactol synthase
5.5.1.n1Transferred entry: 5.4.99.62
5.5.1.n2Transferred entry: 5.5.1.19
5.6.1.1microtubule-severing ATPase
5.6.1.2dynein ATPase
5.6.1.3plus-end-directed kinesin ATPase
5.6.1.4minus-end-directed kinesin ATPase
5.6.1.5proteasome ATPase
5.6.1.6channel-conductance-controlling ATPase
5.6.1.7chaperonin ATPase
5.6.1.8myosin ATPase
5.6.1.9(R)-2-hydroxyacyl-CoA dehydratase activating ATPase
5.6.2.1DNA topoisomerase
5.6.2.2DNA topoisomerase (ATP-hydrolyzing)
5.6.2.3DNA 5'-3' helicase
5.6.2.4DNA 3'-5' helicase
5.99.1.1thiocyanate isomerase
5.99.1.2Transferred entry: 5.6.2.1
5.99.1.3Transferred entry: 5.6.2.2
5.99.1.42-hydroxychromene-2-carboxylate isomerase