A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 5.1.3.24
| Accepted Name |
|---|
| N-acetylneuraminate epimerase.
|
| Alternative Name(s) |
|---|
| Alpha-N-acetylneuraminic acid epimerase. |
| Sialic acid epimerase. |
| Sialic acid mutarotase. |
| Reaction catalysed |
|---|
| N-acetyl-alpha-neuraminate <=> N-acetyl-beta-neuraminate |
| Comment(s) |
|---|
- Sialoglycoconjugates present in vertebrates are linked exclusively by
alpha-linkages and are released in alpha form during degradation.
- This enzyme accelerates maturotation to the beta form (which also
occurs as a slow spontaneous reaction), which is necessary for
further metabolism by the bacteria.
- Formerly EC 5.1.3.n1.
|
| Cross-references |
|---|
| BRENDA | 5.1.3.24 |
| EC2PDB | 5.1.3.24 |
| ExplorEnz | 5.1.3.24 |
| PRIAM enzyme-specific profiles | 5.1.3.24 |
| KEGG Ligand Database for Enzyme Nomenclature | 5.1.3.24 |
| IUBMB Enzyme Nomenclature | 5.1.3.24 |
| IntEnz | 5.1.3.24 |
| MEDLINE | Find literature relating to 5.1.3.24 |
| MetaCyc | 5.1.3.24 |
| UniProtKB/Swiss-Prot |
| Q8CVR2, NANM1_ECOL6; | Q8CVG5, NANM2_ECOL6; | Q2YK69, NANM_BRUA2; |
| Q577K1, NANM_BRUAB; | Q8YBP3, NANM_BRUME; | A5VU94, NANM_BRUO2; |
| A9WYA0, NANM_BRUSI; | A7ZVK8, NANM_ECO24; | Q8X554, NANM_ECO57; |
| A8A834, NANM_ECOHS; | A1AJH6, NANM_ECOK1; | Q0T900, NANM_ECOL5; |
| P39371, NANM_ECOLI; | Q1R2K5, NANM_ECOUT; | Q4QP39, NANM_HAEI8; |
| A5UB03, NANM_HAEIE; | A5UFV3, NANM_HAEIG; | P44544, NANM_HAEIN; |
| Q9CKB7, NANM_PASMU; | A9MH34, NANM_SALAR; | Q57QM5, NANM_SALCH; |
| B5R066, NANM_SALEP; | B4T2W1, NANM_SALNS; | A9N6P2, NANM_SALPB; |
| B4TSP0, NANM_SALSV; | Q8Z7N0, NANM_SALTI; | Q8ZQ34, NANM_SALTY; |
| Q31T32, NANM_SHIBS; | Q0SXL5, NANM_SHIF8; | Q83IN1, NANM_SHIFL; |
| Q3YU63, NANM_SHISS; | A5F7B3, NANM_VIBC3; | Q9KR69, NANM_VIBCH; |
| Q7MD39, NANM_VIBVY; | A1JMV0, NANM_YERE8; | A7FJ01, NANM_YERP3; |
| Q1C8L8, NANM_YERPA; | Q7CI10, NANM_YERPE; | Q1CHD7, NANM_YERPN; |
| A4TK48, NANM_YERPP; | Q66BP2, NANM_YERPS; |
|
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