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ENZYME

ENZYME entry: EC 5.3.1.14

PURL: https://purl.expasy.org/enzyme/EC/5.3.1.14
Accepted Name
L-rhamnose isomerase
Alternative Name(s)
rhamnose isomerase
Reaction catalysed
L-rhamnopyranose = L-rhamnulose
Comment(s)
  • The enzyme binds the closed ring form of the substrate and catalyzes ring opening to generate a form of open-chain conformation that is coordinated to one of the metal sites.
  • Isomerization proceeds via a hydride-shift mechanism.
  • While the enzyme from the bacterium Escherichia coli is specific for L-rhamnose, the enzyme from the bacterium Pseudomonas stutzeri has broad substrate specificity and catalyzes the interconversion of L-mannose and L-fructose, L-lyxose and L-xylulose, D-ribose and D-ribulose, and D-allose and D-psicose.
Cross-references
BRENDA5.3.1.14
EC2PDB5.3.1.14
ExplorEnz5.3.1.14
KEGG Ligand Database for Enzyme Nomenclature5.3.1.14
IUBMB Enzyme Nomenclature5.3.1.14
MEDLINEFind literature relating to 5.3.1.14
MetaCyc5.3.1.14
Rhea expert-curated reactions5.3.1.14
UniProtKB/Swiss-Prot
Q5WL39, RHAAB_SHOC1O05264, RHAA_BACSUQ8A1A2, RHAA_BACTN
A8AL30, RHAA_CITK8A6LQK4, RHAA_CLOB8A7ML61, RHAA_CROS8
A7ZUB4, RHAA_ECO24B7UNM4, RHAA_ECO27B7MI35, RHAA_ECO45
B7L9F3, RHAA_ECO55P58506, RHAA_ECO57B5YZ40, RHAA_ECO5E
B7NUA3, RHAA_ECO7IB7MQZ3, RHAA_ECO81B7M6V5, RHAA_ECO8A
C5A071, RHAA_ECOBWB1XB70, RHAA_ECODHA8A706, RHAA_ECOHS
A1AI80, RHAA_ECOK1Q0TAG0, RHAA_ECOL5Q8FBE0, RHAA_ECOL6
B1IVH5, RHAA_ECOLCP32170, RHAA_ECOLIB7NFK1, RHAA_ECOLU
B6I4P5, RHAA_ECOSEB1LMU3, RHAA_ECOSMA4WG93, RHAA_ENT38
Q838L2, RHAA_ENTFAB7LVE0, RHAA_ESCF3Q9KCL9, RHAA_HALH5
A6TGA7, RHAA_KLEP7B5XZ52, RHAA_KLEV3Q88S51, RHAA_LACPL
Q926R1, RHAA_LISINC1L0I1, RHAA_LISMCQ71VR4, RHAA_LISMF
B8DCW2, RHAA_LISMHQ8Y3I7, RHAA_LISMOQ65Q25, RHAA_MANSM
Q8ESX0, RHAA_OCEIHQ6DA24, RHAA_PECASC6DJR2, RHAA_PECCP
Q7UYE5, RHAA_RHOBAB5F0M7, RHAA_SALA4A9MI67, RHAA_SALAR
Q57HH0, RHAA_SALCHB5FPP3, RHAA_SALDCB5QWY2, RHAA_SALEP
B5RFC5, RHAA_SALG2B4TBY1, RHAA_SALHSB4SZZ1, RHAA_SALNS
Q5PKG4, RHAA_SALPAA9MZC5, RHAA_SALPBC0Q3L2, RHAA_SALPC
B5BJG6, RHAA_SALPKB4TPQ7, RHAA_SALSVQ8Z2V3, RHAA_SALTI
P27031, RHAA_SALTYQ31U86, RHAA_SHIBSQ0SZ93, RHAA_SHIF8
Q83IU4, RHAA_SHIFLQ3YV73, RHAA_SHISSC4LCV5, RHAA_TOLAT
A7FN82, RHAA_YERP3Q1C0V8, RHAA_YERPAB2K1W1, RHAA_YERPB
P58507, RHAA_YERPEA9QYS2, RHAA_YERPGQ1CEB2, RHAA_YERPN
A4TRT1, RHAA_YERPPQ66FF4, RHAA_YERPSB1JNC9, RHAA_YERPY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.3.-.-
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