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ENZYME

ENZYME entry: EC 5.3.1.28

PURL: https://purl.expasy.org/enzyme/EC/5.3.1.28
Accepted Name
D-sedoheptulose-7-phosphate isomerase
Alternative Name(s)
phosphoheptose isomerase
sedoheptulose-7-phosphate isomerase
Reaction catalysed
2 D-sedoheptulose 7-phosphate = D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate
Comment(s)
  • In Gram-negative bacteria the enzyme is involved in biosynthesis of ADP-L-glycero-beta-D-manno-heptose, which is utilized for assembly of the lipopolysaccharide inner core.
  • In Gram-positive bacteria the enzyme is involved in biosynthesis of GDP-D-glycero-alpha-D-manno-heptose, which is required for assembly of S-layer glycoprotein.
Cross-references
BRENDA5.3.1.28
EC2PDB5.3.1.28
ExplorEnz5.3.1.28
KEGG Ligand Database for Enzyme Nomenclature5.3.1.28
IUBMB Enzyme Nomenclature5.3.1.28
MEDLINEFind literature relating to 5.3.1.28
MetaCyc5.3.1.28
Rhea expert-curated reactions5.3.1.28
UniProtKB/Swiss-Prot
Q9PNE6, GMHA1_CAMJEQ9PMN3, GMHA2_CAMJEA3N0F8, GMHA_ACTP2
B3H1D8, GMHA_ACTP7B0BP79, GMHA_ACTPJA6VLR0, GMHA_ACTSZ
A0KIK9, GMHA_AERHHA4SPH9, GMHA_AERS4B2UNE0, GMHA_AKKM8
A8EVR5, GMHA_ALIB4Q0A6I9, GMHA_ALKEHB4RXI5, GMHA_ALTMD
Q9AGY7, GMHA_ANETHO67054, GMHA_AQUAEQ5P6Y3, GMHA_AROAE
A1K3T2, GMHA_AZOSBC1DQ86, GMHA_AZOVDQ2KU87, GMHA_BORA1
A5EN81, GMHA_BRASBA4YYB9, GMHA_BRASOB8D943, GMHA_BUCA5
P57338, GMHA_BUCAIQ8K9R9, GMHA_BUCAPB8D7E7, GMHA_BUCAT
Q9AI36, GMHA_BURMAQ3JP41, GMHA_BURP1Q93UJ2, GMHA_BURPS
A7ZE25, GMHA_CAMC1A8FMK7, GMHA_CAMJ8B9KFJ1, GMHA_CAMLR
Q3AUB6, GMHA_CHLCHB3EHV1, GMHA_CHLL2B3QL68, GMHA_CHLP8
A1BJG0, GMHA_CHLPDA4SGN4, GMHA_CHLPMQ8KAW3, GMHA_CHLTE
Q1QVF5, GMHA_CHRI1B5EGN2, GMHA_CITBBQ97EQ4, GMHA_CLOAB
Q47VU0, GMHA_COLP3B6J4R0, GMHA_COXB1B6J2U5, GMHA_COXB2
A9KBY6, GMHA_COXBNA9NAA5, GMHA_COXBRQ83AY4, GMHA_COXBU
B1WYG5, GMHA_CROS5A7MI45, GMHA_CROS8Q11Y71, GMHA_CYTH3
Q47IS3, GMHA_DECARB8J0B1, GMHA_DESDAA7ZHY1, GMHA_ECO24
B7UJB5, GMHA_ECO27B7MC74, GMHA_ECO45B7LHF3, GMHA_ECO55
P63225, GMHA_ECO57B5Z0M1, GMHA_ECO5EB7NKV9, GMHA_ECO7I
B7MQ59, GMHA_ECO81B7M252, GMHA_ECO8AC4ZRV8, GMHA_ECOBW
B1XD84, GMHA_ECODHA7ZWI6, GMHA_ECOHSQ0TL93, GMHA_ECOL5
P63226, GMHA_ECOL6B1IPP6, GMHA_ECOLCP63224, GMHA_ECOLI
B7N8A8, GMHA_ECOLUB6HZW0, GMHA_ECOSEB1LHM8, GMHA_ECOSM
C5B7W2, GMHA_EDWI9A4W6W5, GMHA_ENT38B2VIQ7, GMHA_ERWT9
B7LW94, GMHA_ESCF3Q8R6A2, GMHA_FUSNNB9M5R7, GMHA_GEODF
Q39X62, GMHA_GEOMGQ74BF4, GMHA_GEOSLC6E6C5, GMHA_GEOSM
A5G5G9, GMHA_GEOURB8F3D3, GMHA_GLAP5Q0BRW8, GMHA_GRABC
O87340, GMHA_HAEDUQ4QLB7, GMHA_HAEI8A5UCS8, GMHA_HAEIE
A5UIU8, GMHA_HAEIGP45093, GMHA_HAEINA1WYV6, GMHA_HALHL
C4K7X8, GMHA_HAMD5Q7VFZ4, GMHA_HELHPB6JM81, GMHA_HELP2
Q1CT15, GMHA_HELPHQ9ZKZ1, GMHA_HELPJB2USX3, GMHA_HELPS
O25528, GMHA_HELPYB0USS3, GMHA_HISS2A6T518, GMHA_KLEP7
B5Y1F4, GMHA_KLEV3C1D5I3, GMHA_LARHHB0SHL8, GMHA_LEPBA
Q04RN4, GMHA_LEPBJQ051Y7, GMHA_LEPBLB0SR27, GMHA_LEPBP
Q72RC1, GMHA_LEPICQ8F4E9, GMHA_LEPINC6C0L8, GMHA_MARSD
Q60CC5, GMHA_METCAQ58731, GMHA_METJAA2SMC9, GMHA_METPP
P0A605, GMHA_MYCBOA1KET4, GMHA_MYCBPC1AJD9, GMHA_MYCBT
A5TYI7, GMHA_MYCTAP9WGG0, GMHA_MYCTOP9WGG1, GMHA_MYCTU
Q5F5E3, GMHA_NEIG1B4RQP9, GMHA_NEIG2A9M479, GMHA_NEIM0
P0A0Y5, GMHA_NEIMAP0A0Y6, GMHA_NEIMBA1KWG6, GMHA_NEIMF
A6Q4Z5, GMHA_NITSBQ72AV1, GMHA_NITV2B8DKW0, GMHA_NITV9
Q2WBD9, GMHA_PARM1P57814, GMHA_PASMUQ6D1H3, GMHA_PECAS
C6DCY7, GMHA_PECCPB4SGD2, GMHA_PELPBA1AV13, GMHA_PELPD
Q7N7F7, GMHA_PHOLLB4EUT1, GMHA_PROMHQ15PJ1, GMHA_PSEA6
B7UZK3, GMHA_PSEA8Q02H15, GMHA_PSEABQ9HVZ0, GMHA_PSEAE
Q1I5A5, GMHA_PSEE4C3KBY0, GMHA_PSEFSA5W8R3, GMHA_PSEP1
A6VB98, GMHA_PSEP7Q3K731, GMHA_PSEPFB0KFT9, GMHA_PSEPG
B1J1X7, GMHA_PSEPWQ4ZNX7, GMHA_PSEU2A1SUJ5, GMHA_PSYIN
Q2RR43, GMHA_RHORTA5UVV6, GMHA_ROSS1B5EWJ3, GMHA_SALA4
Q57SU4, GMHA_SALCHB5FJW2, GMHA_SALDCB5R470, GMHA_SALEP
B5R5Q7, GMHA_SALG2B4T7P3, GMHA_SALHSB4SVV2, GMHA_SALNS
Q5PF73, GMHA_SALPAA9MY16, GMHA_SALPBB5BDQ9, GMHA_SALPK
B4TYM6, GMHA_SALSVP63222, GMHA_SALTIP63223, GMHA_SALTY
A8GAB6, GMHA_SERP5A1SB02, GMHA_SHEAMB8EBE0, GMHA_SHEB2
A3DA03, GMHA_SHEB5A6WTQ0, GMHA_SHEB8A9L683, GMHA_SHEB9
Q12SK9, GMHA_SHEDOQ088R5, GMHA_SHEFNB0TL65, GMHA_SHEHH
A3Q9E9, GMHA_SHELPQ8EK08, GMHA_SHEONA8GZ41, GMHA_SHEPA
A4YBR9, GMHA_SHEPCB8CNK0, GMHA_SHEPWA0L231, GMHA_SHESA
A8G184, GMHA_SHESHQ0HDW8, GMHA_SHESMQ0I041, GMHA_SHESR
A1RPP6, GMHA_SHESWB1KP81, GMHA_SHEWMB2U3R4, GMHA_SHIB3
Q325S4, GMHA_SHIBSQ32JN6, GMHA_SHIDSP63227, GMHA_SHIFL
Q3Z5B4, GMHA_SHISSQ2NVF5, GMHA_SODGMC4XJU6, GMHA_SOLM1
Q9Z5B6, GMHA_STRCOQ30T29, GMHA_SULDNQ3A538, GMHA_SYNC1
Q55797, GMHA_SYNY3Q9HJV9, GMHA_THEACQ97A25, GMHA_THEVO
B5YJT7, GMHA_THEYDQ3SMI5, GMHA_THIDAC4LC62, GMHA_TOLAT
B3E5N0, GMHA_TRIL1Q9KPY2, GMHA_VIBCHQ87MG7, GMHA_VIBPA
Q8DBC5, GMHA_VIBVUQ7M9U0, GMHA_WOLSUA1JP02, GMHA_YERE8
A7FLK2, GMHA_YERP3Q1C4C6, GMHA_YERPAQ8ZBY7, GMHA_YERPE
A9R2Y9, GMHA_YERPGQ1CLE7, GMHA_YERPNA4TPM1, GMHA_YERPP
B1JIJ3, GMHA_YERPY

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-