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ENZYME

ENZYME entry: EC 5.3.1.4

Accepted Name
L-arabinose isomerase
Alternative Name(s)
L-arabinose ketol-isomerase
Reaction catalysed
beta-L-arabinopyranose = L-ribulose
Comment(s)
  • Requires a divalent metal ion (the enzyme from the bacterium Escherichia coli prefers Mn(2+)).
  • The enzyme binds beta-L-arabinopyranose and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene-diol mechanism.
  • The enzyme can also convert alpha-D-galactose to D-tagatose with lower efficiency.
Cross-references
BRENDA5.3.1.4
EC2PDB5.3.1.4
ExplorEnz5.3.1.4
PRIAM enzyme-specific profiles5.3.1.4
KEGG Ligand Database for Enzyme Nomenclature5.3.1.4
IUBMB Enzyme Nomenclature5.3.1.4
IntEnz5.3.1.4
MEDLINEFind literature relating to 5.3.1.4
MetaCyc5.3.1.4
Rhea expert-curated reactions5.3.1.4
UniProtKB/Swiss-Prot
Q65GC0, ARAA1_BACLDQ97JE4, ARAA1_CLOABQ65J10, ARAA2_BACLD
Q97JE0, ARAA2_CLOABA0LT86, ARAA_ACIC1A6VLM2, ARAA_ACTSZ
A0KJI0, ARAA_AERHHA4SNH3, ARAA_AERS4B7GGW0, ARAA_ANOFW
A0JRF5, ARAA_ARTS2P94523, ARAA_BACSUQ8AAW1, ARAA_BACTN
B8DV60, ARAA_BIFA0A1A3A8, ARAA_BIFAAB3DTJ5, ARAA_BIFLD
Q8G7J3, ARAA_BIFLOB3PD57, ARAA_CELJUA0LZ81, ARAA_CHRFK
A8ALP0, ARAA_CITK8A5CPB7, ARAA_CLAM3B0RIE3, ARAA_CLASE
A6M1T6, ARAA_CLOB8A7ZHF3, ARAA_ECO24B7UIA8, ARAA_ECO27
B7MAI5, ARAA_ECO45B7L4I3, ARAA_ECO55P58538, ARAA_ECO57
B5YZ98, ARAA_ECO5EB7NHG8, ARAA_ECO7IB7MNR9, ARAA_ECO81
B7M0F7, ARAA_ECO8AC4ZPY5, ARAA_ECOBWA7ZW12, ARAA_ECOHS
A1A7A9, ARAA_ECOK1Q0TLS8, ARAA_ECOL5Q8FL89, ARAA_ECOL6
B1IRB6, ARAA_ECOLCP08202, ARAA_ECOLIB7N7T6, ARAA_ECOLU
B6HZ42, ARAA_ECOSEB1LFZ6, ARAA_ECOSMQ1RGD7, ARAA_ECOUT
A4W6G6, ARAA_ENT38B2VER0, ARAA_ERWT9B7LVT3, ARAA_ESCF3
A5FKW3, ARAA_FLAJ1Q5KYP7, ARAA_GEOKAQ9S467, ARAA_GEOSE
A4IPA1, ARAA_GEOTNQ9KBQ2, ARAA_HALH5A9B689, ARAA_HERA2
B5Y1Y1, ARAA_KLEP3A6T4K0, ARAA_KLEP7Q48433, ARAA_KLEPN
Q1IUW9, ARAA_KORVEQ88S84, ARAA_LACPLQ38UH2, ARAA_LATSS
B1Y1J9, ARAA_LEPCPQ03XW2, ARAA_LEUMMQ03PR5, ARAA_LEVBA
Q65WJ5, ARAA_MANSMA0QT53, ARAA_MYCS2Q9RHG2, ARAA_MYCSM
A1SDP0, ARAA_NOCSJQ8EMP4, ARAA_OCEIHB1ZRZ1, ARAA_OPITP
A1RAY5, ARAA_PAEATQ6D4W5, ARAA_PECASC6DH19, ARAA_PECCP
Q03HQ0, ARAA_PEDPAA6L2R5, ARAA_PHOV8Q21MP3, ARAA_SACD2
B5F783, ARAA_SALA4A9MQF1, ARAA_SALARQ57TF9, ARAA_SALCH
B5FI45, ARAA_SALDCB5R1T9, ARAA_SALEPB5RGD3, ARAA_SALG2
B4TJ59, ARAA_SALHSB4SU23, ARAA_SALNSQ5PDF2, ARAA_SALPA
A9MYN8, ARAA_SALPBB5BL43, ARAA_SALPKB4TWU8, ARAA_SALSV
P58539, ARAA_SALTIP06189, ARAA_SALTYA8GE04, ARAA_SERP5
B8EEN5, ARAA_SHEB2A0KWX7, ARAA_SHESAQ0HIR5, ARAA_SHESM
Q0HV71, ARAA_SHESRA1RJD6, ARAA_SHESWB2U268, ARAA_SHIB3
Q326H3, ARAA_SHIBSQ32K31, ARAA_SHIDSQ0T8D5, ARAA_SHIF8
Q7UDT4, ARAA_SHIFLQ3Z5U9, ARAA_SHISSQ5WL05, ARAA_SHOC1
Q9WYB3, ARAA_THEMAB9KC39, ARAA_THENNA5IKE5, ARAA_THEP1
B1L9M7, ARAA_THESQC4L8B5, ARAA_TOLATQ87FK3, ARAA_VIBPA
A1JMB6, ARAA_YERE8A7FHY4, ARAA_YERP3Q1C7J3, ARAA_YERPA
B2K4K7, ARAA_YERPBP58540, ARAA_YERPEA9R8V1, ARAA_YERPG
Q1CIX9, ARAA_YERPNA4TJ19, ARAA_YERPPQ66AF8, ARAA_YERPS
B1JKM7, ARAA_YERPY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-