Expasy logo

ENZYME

ENZYME entry: EC 5.3.3.12

PURL: https://purl.expasy.org/enzyme/EC/5.3.3.12
Accepted Name
L-dopachrome isomerase
Alternative Name(s)
DCF
DCT
dopachrome conversion factor
dopachrome Delta(7),Delta(2)-isomerase
dopachrome Delta-isomerase
dopachrome isomerase
dopachrome keto-enol isomerase
dopachrome oxidoreductase
dopachrome rearranging enzyme
dopachrome tautomerase
L-dopachrome-methyl ester tautomerase
TRP
tyrosinase-related protein 2
Reaction catalysed
L-dopachrome = 5,6-dihydroxyindole-2-carboxylate
Comment(s)
  • Stereospecific for L-dopachrome (5,6-dioxo-2,3-5,6-tetrahydroindole- 2-carboxylate).
  • Dopachrome methyl ester is a substrate, but dopaminochrome (2,3- dihydroxyindolyl-5,6-quinone) is not (see also EC 4.1.1.84).
Cross-references
BRENDA5.3.3.12
EC2PDB5.3.3.12
ExplorEnz5.3.3.12
KEGG Ligand Database for Enzyme Nomenclature5.3.3.12
IUBMB Enzyme Nomenclature5.3.3.12
MEDLINEFind literature relating to 5.3.3.12
MetaCyc5.3.3.12
Rhea expert-curated reactions5.3.3.12
UniProtKB/Swiss-Prot
Q963F7, MIFH1_ONCVOP91850, MIFH_BRUMAP81530, MIFH_TRIMR
P81529, MIFH_TRISPP81748, MIFH_TRITRO44786, MIFH_WUCBA
P80177, MIF_BOVINQ02960, MIF_CHICKP14174, MIF_HUMAN
Q4R549, MIF_MACFAQ6DN04, MIF_MACMUO55052, MIF_MERUN
P34884, MIF_MOUSEP80928, MIF_PIGP30904, MIF_RAT
Q1ZZU7, MIF_SHEEPQ76BK2, MIF_XENLAA9JSE7, MIF_XENTR
Q95119, TYRP2_BOVINO93505, TYRP2_CHICKP40126, TYRP2_HUMAN
P29812, TYRP2_MOUSEQ4R1H1, TYRP2_PIGQ9VG08, YELF2_DROME
Q9VG09, YELF_DROME

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.3.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-