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ENZYME

ENZYME entry: EC 5.3.3.18

Accepted Name
2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase
Alternative Name(s)
1,2-epoxyphenylacetyl-CoA isomerase
Reaction catalysed
2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA = 2-oxepin-2(3H)-ylideneacetyl-CoA
Comment(s)
The enzyme catalyzes the reversible isomerization of 2-(1,2-epoxy- 1,2-dihydrophenyl)acetyl-CoA to the unusual unsaturated, oxygen- containing, seven-member heterocyclic enol ether 2-oxepin-2(3H)- ylideneacetyl-CoA, as part of an aerobic phenylacetate degradation pathway.
Cross-references
BRENDA5.3.3.18
EC2PDB5.3.3.18
ExplorEnz5.3.3.18
PRIAM enzyme-specific profiles5.3.3.18
KEGG Ligand Database for Enzyme Nomenclature5.3.3.18
IUBMB Enzyme Nomenclature5.3.3.18
IntEnz5.3.3.18
MEDLINEFind literature relating to 5.3.3.18
MetaCyc5.3.3.18
Rhea expert-curated reactions5.3.3.18
UniProtKB/Swiss-Prot
P77467, PAAG_ECOLI

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