Expasy logo

ENZYME

ENZYME entry: EC 5.3.3.21

PURL: https://purl.expasy.org/enzyme/EC/5.3.3.21
Accepted Name
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase
Alternative Name(s)
3,5-tetradecadienoyl-CoA isomerase
Reaction catalysed
a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA
Comment(s)
  • The enzyme participates in an alternative degradation route of fatty acids with cis-double bonds on odd-number carbons such as oleate and linoleate.
  • The main physiological substrate is (3E,5Z)-tetradeca-3,5-dienoyl- CoA, but other (3E,5Z)-dienoyl-CoAs with varying carbon chain lengths are also substrates.
Cross-references
BRENDA5.3.3.21
EC2PDB5.3.3.21
ExplorEnz5.3.3.21
KEGG Ligand Database for Enzyme Nomenclature5.3.3.21
IUBMB Enzyme Nomenclature5.3.3.21
MEDLINEFind literature relating to 5.3.3.21
MetaCyc5.3.3.21
Rhea expert-curated reactions5.3.3.21
UniProtKB/Swiss-Prot
Q9FHR8, DCI1_ARATHG4NCP4, DCI1_PYRO7Q08558, DCI1_YEAST
Q13011, ECH1_HUMANO35459, ECH1_MOUSEQ5RFG0, ECH1_PONAB
Q62651, ECH1_RAT

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.3.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-