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ENZYME entry: EC 5.3.4.1

Accepted Name
Protein disulfide-isomerase.
Alternative Name(s)
S-S rearrangase.
Reaction catalysed
Catalyzes the rearrangement of -S-S- bonds in proteins
Comment(s)
Needs reducing agents or partly reduced enzyme; the reaction depends on sulfhydryl-disulfide interchange.
Cross-references
PROSITEPDOC00172
BRENDA5.3.4.1
EC2PDB5.3.4.1
ExplorEnz5.3.4.1
PRIAM enzyme-specific profiles5.3.4.1
KEGG Ligand Database for Enzyme Nomenclature5.3.4.1
IUBMB Enzyme Nomenclature5.3.4.1
IntEnz5.3.4.1
MEDLINEFind literature relating to 5.3.4.1
MetaCyc5.3.4.1
UniProtKB/Swiss-Prot
Q5EA46, CREL1_BOVIN;  Q19267, CREL1_CAEEL;  Q96HD1, CREL1_HUMAN;  
Q91XD7, CREL1_MOUSE;  Q4V7F2, CREL1_RAT;  Q2KIT5, CREL2_BOVIN;  
Q60438, CREL2_CRIGR;  Q6UXH1, CREL2_HUMAN;  Q9CYA0, CREL2_MOUSE;  
Q4G063, CREL2_RAT;  P40557, EPS1_YEAST;  Q92249, ERP38_NEUCR;  
P38658, ERP60_SCHMA;  P32474, EUG1_YEAST;  Q8GSJ6, LQY1_ARATH;  
Q12404, MPD1_YEAST;  Q99316, MPD2_YEAST;  Q9XI01, PDI11_ARATH;  
Q53LQ0, PDI11_ORYSJ;  Q9SRG3, PDI12_ARATH;  Q7XRB5, PDI12_ORYSJ;  
Q8VX13, PDI13_ARATH;  Q9FF55, PDI14_ARATH;  Q67IX6, PDI14_ORYSJ;  
A3KPF5, PDI15_ARATH;  Q5WA72, PDI15_ORYSJ;  Q66GQ3, PDI16_ARATH;  
Q17967, PDI1_CAEEL;  Q86IA3, PDI1_DICDI;  Q10057, PDI1_SCHPO;  
O22263, PDI21_ARATH;  Q75M08, PDI21_ORYSJ;  Q9MAU6, PDI22_ARATH;  
Q942L2, PDI22_ORYSJ;  O48773, PDI23_ARATH;  Q67UF5, PDI23_ORYSJ;  
Q17770, PDI2_CAEEL;  Q54EN4, PDI2_DICDI;  O13811, PDI2_SCHPO;  
P05307, PDIA1_BOVIN;  P09102, PDIA1_CHICK;  Q8R4U2, PDIA1_CRIGR;  
P07237, PDIA1_HUMAN;  Q2HWU2, PDIA1_MACFU;  P09103, PDIA1_MOUSE;  
Q5R5B6, PDIA1_PONAB;  P21195, PDIA1_RABIT;  P04785, PDIA1_RAT;  
Q13087, PDIA2_HUMAN;  D3Z6P0, PDIA2_MOUSE;  Q5RCH2, PDIA2_PONAB;  
P38657, PDIA3_BOVIN;  Q8JG64, PDIA3_CHICK;  Q4VIT4, PDIA3_CHLAE;  
P30101, PDIA3_HUMAN;  P86235, PDIA3_MESAU;  P27773, PDIA3_MOUSE;  
P81246, PDIA3_PAPHA;  Q5RDG4, PDIA3_PONAB;  P11598, PDIA3_RAT;  
Q29RV1, PDIA4_BOVIN;  P34329, PDIA4_CAEEL;  P13667, PDIA4_HUMAN;  
P08003, PDIA4_MOUSE;  P38659, PDIA4_RAT;  Q2KIL5, PDIA5_BOVIN;  
Q14554, PDIA5_HUMAN;  Q921X9, PDIA5_MOUSE;  Q5I0H9, PDIA5_RAT;  
Q11067, PDIA6_CAEEL;  Q9V438, PDIA6_DROME;  Q15084, PDIA6_HUMAN;  
P38661, PDIA6_MEDSA;  P38660, PDIA6_MESAU;  Q922R8, PDIA6_MOUSE;  
Q5R6T1, PDIA6_PONAB;  Q63081, PDIA6_RAT;  Q00002, PDI_ALTAL;  
D4B2L8, PDI_ARTBC;  Q12730, PDI_ASPNG;  Q00248, PDI_ASPOR;  
Q9XF61, PDI_DATGL;  P54399, PDI_DROME;  P80284, PDI_HORVU;  
P55059, PDI_HUMIN;  P52588, PDI_MAIZE;  P29828, PDI_MEDSA;  
Q43116, PDI_RICCO;  P52589, PDI_WHEAT;  P17967, PDI_YEAST;  
Q69ST6, PID13_ORYSJ;  A1A6M1, PTAC5_ARATH;  Q93YN0, SCO2_ARATH;  
Q00216, TIGA_ASPNG;  Q96JJ7, TMX3_HUMAN;  Q8BXZ1, TMX3_MOUSE;  
Q5R875, TMX3_PONAB;  Q6GNG3, TMX3_XENLA;  Q869Z0, Y5025_DICDI;  
Q9P4X1, YKV5_SCHPO;  

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