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ENZYME entry: EC 5.3.99.2

Accepted Name
Prostaglandin-D synthase.
Alternative Name(s)
PGD2 synthase.
PGH-PGD isomerase.
Prostaglandin D synthetase.
Prostaglandin D2 synthase.
Prostaglandin endoperoxide Delta-isomerase.
Prostaglandin-H(2) Delta-isomerase.
Reaction catalysed
(5Z,13E,15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate <=> (5Z,13E,15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate
Cofactor(s)
Glutathione.
Comment(s)
Brings about the opening of the epidioxy bridge.
Cross-references
PROSITEPDOC00187
BRENDA5.3.99.2
EC2PDB5.3.99.2
ExplorEnz5.3.99.2
PRIAM enzyme-specific profiles5.3.99.2
KEGG Ligand Database for Enzyme Nomenclature5.3.99.2
IUBMB Enzyme Nomenclature5.3.99.2
IntEnz5.3.99.2
MEDLINEFind literature relating to 5.3.99.2
MetaCyc5.3.99.2
UniProtKB/Swiss-Prot
O73888, HPGDS_CHICK;  O60760, HPGDS_HUMAN;  Q9JHF7, HPGDS_MOUSE;  
O35543, HPGDS_RAT;  O02853, PTGDS_BOVIN;  Q9XS65, PTGDS_CANLF;  
Q29487, PTGDS_FELCA;  Q8WNM1, PTGDS_GORGO;  O97921, PTGDS_HORSE;  
P41222, PTGDS_HUMAN;  Q9TUI1, PTGDS_MACFU;  O09114, PTGDS_MOUSE;  
Q29095, PTGDS_PIG;  Q8WNM0, PTGDS_PONPY;  P22057, PTGDS_RAT;  
Q9XSM0, PTGDS_SHEEP;  Q29562, PTGDS_URSAR;  

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