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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 5.4.3.3

Accepted Name
Lysine 5,6-aminomutase.
Alternative Name(s)
Adenosylcobalamin-dependent D-lysine 5,6-aminomutase.
Beta-lysine 5,6-aminomutase.
Beta-lysine mutase.
D-lysine 5,6-aminomutase.
Reaction catalysed
  • (3S)-3,6-diaminohexanoate <=> (3S,5S)-3,5-diaminohexanoate
  • D-lysine <=> 2,5-diaminohexanoate
Cofactor(s)
Cob(II)alamin; Pyridoxal 5'-phosphate.
Comment(s)
  • This enzyme is a member of the 'AdoMet radical' (radical SAM) family.
  • A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.
  • Formerly EC 5.4.3.4.
Cross-references
BRENDA5.4.3.3
EC2PDB5.4.3.3
ExplorEnz5.4.3.3
PRIAM enzyme-specific profiles5.4.3.3
KEGG Ligand Database for Enzyme Nomenclature5.4.3.3
IUBMB Enzyme Nomenclature5.4.3.3
IntEnz5.4.3.3
MEDLINEFind literature relating to 5.4.3.3
MetaCyc5.4.3.3
UniProtKB/Swiss-Prot
E3PRJ5, KAMD_ACESD;  Q8RHX7, KAMD_FUSNN;  E3PRJ4, KAME_ACESD;  
Q8RHX8, KAME_FUSNN;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.4.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-