Expasy logo

ENZYME

ENZYME entry: EC 5.4.3.3

PURL: https://purl.expasy.org/enzyme/EC/5.4.3.3
Accepted Name
lysine 5,6-aminomutase
Alternative Name(s)
adenosylcobalamin-dependent D-lysine 5,6-aminomutase
beta-lysine 5,6-aminomutase
beta-lysine mutase
D-lysine 5,6-aminomutase
Reaction catalysed
  • (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate
  • D-lysine = (2R,5S)-2,5-diaminohexanoate
Comment(s)
  • This enzyme is a member of the 'AdoMet radical' (radical SAM) family.
  • A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.
  • Formerly EC 5.4.3.4.
Cross-references
BRENDA5.4.3.3
EC2PDB5.4.3.3
ExplorEnz5.4.3.3
KEGG Ligand Database for Enzyme Nomenclature5.4.3.3
IUBMB Enzyme Nomenclature5.4.3.3
MEDLINEFind literature relating to 5.4.3.3
MetaCyc5.4.3.3
Rhea expert-curated reactions5.4.3.3
UniProtKB/Swiss-Prot
E3PRJ5, KAMD_ACESDQ8RHX7, KAMD_FUSNNE3PRJ4, KAME_ACESD
Q8RHX8, KAME_FUSNN

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.4.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-