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ENZYME entry: EC 5.5.1.11

Accepted Name
Dichloromuconate cycloisomerase.
Reaction catalysed
2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate <=> 2,4-dichloro-cis,cis-muconate
Cofactor(s)
Mn(2+).
Comment(s)
  • The product of cyclisomerization of dichloro-cis,cis-muconate spontaneously eliminates chloride to produce cis-4-carboxymethylene- 3-chlorobut-2-en-4-olide.
  • Also acts, in the reverse direction, on cis,cis-muconate and its monochloro-derivatives, but with lower affinity.
  • Not identical with EC 5.5.1.1 or EC 5.5.1.7.
Cross-references
BRENDA5.5.1.11
EC2PDB5.5.1.11
ExplorEnz5.5.1.11
PRIAM enzyme-specific profiles5.5.1.11
KEGG Ligand Database for Enzyme Nomenclature5.5.1.11
IUBMB Enzyme Nomenclature5.5.1.11
IntEnz5.5.1.11
MEDLINEFind literature relating to 5.5.1.11
MetaCyc5.5.1.11
Rhea expert-curated reactions5.5.1.11

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-