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ENZYME

ENZYME entry: EC 5.5.1.37

Accepted Name
catharanthine synthase
Reaction catalysed
dehydrosecodine = catharanthine
Comment(s)
  • The enzyme, characterized from the plant Catharanthus roseus (Madagascar periwinkle), is a carboxylesterase-like cyclase that catalyzes a regio- and enantiodivergent [4+2] cycloaddition reaction to generate the iboga scaffold of catharanthine.
  • cf. EC 5.5.1.38.
Cross-references
BRENDA5.5.1.37
EC2PDB5.5.1.37
ExplorEnz5.5.1.37
PRIAM enzyme-specific profiles5.5.1.37
KEGG Ligand Database for Enzyme Nomenclature5.5.1.37
IUBMB Enzyme Nomenclature5.5.1.37
IntEnz5.5.1.37
MEDLINEFind literature relating to 5.5.1.37
MetaCyc5.5.1.37
Rhea expert-curated reactions5.5.1.37
UniProtKB/Swiss-Prot
A0A2P1GIW2, CS_CATRO

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