| Accepted Name |
|---|
| Inositol-3-phosphate synthase.
|
| Alternative Name(s) |
|---|
| 1L-myo-inositol-1-phosphate lyase (isomerizing). |
| D-glucose 6-phosphate cycloaldolase. |
| Glucocycloaldolase. |
| Glucose 6-phosphate cyclase. |
| Inositol 1-phosphate synthetase. |
| Myo-inositol-1-phosphate synthase. |
| Reaction catalysed |
|---|
| D-glucose 6-phosphate <=> 1D-myo-inositol 3-phosphate |
| Cofactor(s) |
|---|
| NAD(+).
|
| Comment(s) |
|---|
| The NAD(+) dehydrogenates the -CHOH- group to -CO- at C-5 of the
glucose 6-phosphate, making C-6 into an active methylene, able to
condense with the -CHO at C-1; finally, the enzyme-bound NADH
reconverts C-5 into the -CHOH- form.
|
| Cross-references |
|---|
| BRENDA | 5.5.1.4 |
| EC2PDB | 5.5.1.4 |
| ExplorEnz | 5.5.1.4 |
| PRIAM enzyme-specific profiles | 5.5.1.4 |
| KEGG Ligand Database for Enzyme Nomenclature | 5.5.1.4 |
| IUBMB Enzyme Nomenclature | 5.5.1.4 |
| IntEnz | 5.5.1.4 |
| MEDLINE | Find literature relating to 5.5.1.4 |
| MetaCyc | 5.5.1.4 |
| UniProtKB/Swiss-Prot |
| Q7ZXY0, INO1A_XENLA; | Q6DDT1, INO1B_XENLA; | P42801, INO1_ARATH; |
| Q2NL29, INO1_BOVIN; | Q96348, INO1_BRANA; | P42800, INO1_CANAL; |
| Q6FQI1, INO1_CANGA; | P42802, INO1_CITPA; | Q54N49, INO1_DICDI; |
| O97477, INO1_DROME; | O65195, INO1_HORVU; | Q9NPH2, INO1_HUMAN; |
| Q4R6E3, INO1_MACFA; | Q9FPK7, INO1_MAIZE; | Q40271, INO1_MESCR; |
| Q9JHU9, INO1_MOUSE; | A0R7G6, INO1_MYCS2; | P9WKI0, INO1_MYCTO; |
| P9WKI1, INO1_MYCTU; | Q9SSV4, INO1_NICPA; | Q41107, INO1_PHAVU; |
| Q6AYK3, INO1_RAT; | Q9FYV1, INO1_SESIN; | P42803, INO1_SPIPO; |
| Q9LW96, INO1_TOBAC; | Q9S7U0, INO1_WHEAT; | P11986, INO1_YEAST; |
| Q38862, INO2_ARATH; | Q9LX12, INO3_ARATH; | O64437, RINO1_ORYSJ; |
| Q8S5N2, RINO2_ORYSJ; |
|