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ENZYME

ENZYME entry: EC 5.5.1.4

Accepted Name
inositol-3-phosphate synthase
Alternative Name(s)
1L-myo-inositol-1-phosphate lyase (isomerizing)
D-glucose 6-phosphate cycloaldolase
glucocycloaldolase
glucose 6-phosphate cyclase
inositol 1-phosphate synthetase
myo-inositol-1-phosphate synthase
Reaction catalysed
D-glucose 6-phosphate <=> 1D-myo-inositol 3-phosphate
Comment(s)
The NAD(+) dehydrogenates the -CHOH- group to -CO- at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the -CHO at C-1; finally, the enzyme-bound NADH reconverts C-5 into the -CHOH- form.
Cross-references
BRENDA5.5.1.4
EC2PDB5.5.1.4
ExplorEnz5.5.1.4
PRIAM enzyme-specific profiles5.5.1.4
KEGG Ligand Database for Enzyme Nomenclature5.5.1.4
IUBMB Enzyme Nomenclature5.5.1.4
IntEnz5.5.1.4
MEDLINEFind literature relating to 5.5.1.4
MetaCyc5.5.1.4
Rhea expert-curated reactions5.5.1.4
UniProtKB/Swiss-Prot
Q7ZXY0, INO1A_XENLAQ6DDT1, INO1B_XENLAP42801, INO1_ARATH
Q8A7J8, INO1_BACTNQ2NL29, INO1_BOVINQ96348, INO1_BRANA
P42800, INO1_CANALQ6FQI1, INO1_CANGAP42802, INO1_CITPA
Q8NLE6, INO1_CORGLJ9VYL3, INO1_CRYNHQ54N49, INO1_DICDI
O97477, INO1_DROMEO65195, INO1_HORVUQ9NPH2, INO1_HUMAN
Q4R6E3, INO1_MACFAQ9FPK7, INO1_MAIZEQ40271, INO1_MESCR
Q9JHU9, INO1_MOUSEA0R7G6, INO1_MYCS2P9WKI0, INO1_MYCTO
P9WKI1, INO1_MYCTUQ9SSV4, INO1_NICPAQ41107, INO1_PHAVU
Q8I3Y8, INO1_PLAF7C0HM53, INO1_POPEUQ6AYK3, INO1_RAT
Q9FYV1, INO1_SESINP42803, INO1_SPIPOQ9LW96, INO1_TOBAC
Q5QQ46, INO1_TRYBBQ9S7U0, INO1_WHEATP11986, INO1_YEAST
Q38862, INO2_ARATHQ9LX12, INO3_ARATHO64437, RINO1_ORYSJ
Q8S5N2, RINO2_ORYSJ

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-