A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 5.5.1.4
Accepted Name |
Inositol-3-phosphate synthase.
|
Alternative Name(s) |
1L-myo-inositol-1-phosphate lyase (isomerizing). |
D-glucose 6-phosphate cycloaldolase. |
Glucocycloaldolase. |
Glucose 6-phosphate cyclase. |
Inositol 1-phosphate synthetase. |
Myo-inositol-1-phosphate synthase. |
Reaction catalysed |
D-glucose 6-phosphate <=> 1D-myo-inositol 3-phosphate |
Cofactor(s) |
NAD(+).
|
Comment(s) |
The NAD(+) dehydrogenates the -CHOH- group to -CO- at C-5 of the
glucose 6-phosphate, making C-6 into an active methylene, able to
condense with the -CHO at C-1; finally, the enzyme-bound NADH
reconverts C-5 into the -CHOH- form.
|
Cross-references |
BRENDA | 5.5.1.4 |
EC2PDB | 5.5.1.4 |
ExplorEnz | 5.5.1.4 |
PRIAM enzyme-specific profiles | 5.5.1.4 |
KEGG Ligand Database for Enzyme Nomenclature | 5.5.1.4 |
IUBMB Enzyme Nomenclature | 5.5.1.4 |
IntEnz | 5.5.1.4 |
MEDLINE | Find literature relating to 5.5.1.4 |
MetaCyc | 5.5.1.4 |
UniProtKB/Swiss-Prot |
Q7ZXY0, INO1A_XENLA; | Q6DDT1, INO1B_XENLA; | P42801, INO1_ARATH; |
Q2NL29, INO1_BOVIN; | Q96348, INO1_BRANA; | P42800, INO1_CANAL; |
Q6FQI1, INO1_CANGA; | P42802, INO1_CITPA; | Q54N49, INO1_DICDI; |
O97477, INO1_DROME; | O65195, INO1_HORVU; | Q9NPH2, INO1_HUMAN; |
Q4R6E3, INO1_MACFA; | Q9FPK7, INO1_MAIZE; | Q40271, INO1_MESCR; |
Q9JHU9, INO1_MOUSE; | A0R7G6, INO1_MYCS2; | P9WKI0, INO1_MYCTO; |
P9WKI1, INO1_MYCTU; | Q9SSV4, INO1_NICPA; | Q41107, INO1_PHAVU; |
Q6AYK3, INO1_RAT; | Q9FYV1, INO1_SESIN; | P42803, INO1_SPIPO; |
Q9LW96, INO1_TOBAC; | Q9S7U0, INO1_WHEAT; | P11986, INO1_YEAST; |
Q38862, INO2_ARATH; | Q9LX12, INO3_ARATH; | O64437, RINO1_ORYSJ; |
Q8S5N2, RINO2_ORYSJ; |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 5.5.1.-
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