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ENZYME

ENZYME entry: EC 5.6.1.1

PURL: https://purl.expasy.org/enzyme/EC/5.6.1.1
Accepted Name
microtubule-severing ATPase
Alternative Name(s)
katanin
Reaction catalysed
n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers
Comment(s)
  • A member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome.
  • Formerly EC 3.6.4.3.
Cross-references
BRENDA5.6.1.1
EC2PDB5.6.1.1
ExplorEnz5.6.1.1
KEGG Ligand Database for Enzyme Nomenclature5.6.1.1
IUBMB Enzyme Nomenclature5.6.1.1
MEDLINEFind literature relating to 5.6.1.1
MetaCyc5.6.1.1
Rhea expert-curated reactions5.6.1.1
UniProtKB/Swiss-Prot
Q5U3S1, KATL1_DANREQ9BW62, KATL1_HUMANQ8K0T4, KATL1_MOUSE
B4USW8, KATL1_OTOGAA9RA82, KATL1_PAPANB7NZ88, KATL1_RABIT
Q5XIK7, KATL1_RATB3EX35, KATL1_SORARQ8IYT4, KATL2_HUMAN
Q9D3R6, KATL2_MOUSEQ3B8D5, KATL2_XENLAA0JMA9, KATL2_XENTR
Q9SEX2, KTNA1_ARATHP34808, KTNA1_CAEELQ1HGK7, KTNA1_CHICK
Q5RII9, KTNA1_DANREO75449, KTNA1_HUMANQ4R407, KTNA1_MACFA
Q9WV86, KTNA1_MOUSEQ6E0V2, KTNA1_RATB5X3X5, KTNA1_SALSA
O61577, KTNA1_STRPUQ9PUL2, KTNA1_XENLAQ0IIR9, KTNA1_XENTR
Q7QBW0, SPAST_ANOGAA2VDN5, SPAST_BOVINA8QFF6, SPAST_BRUMA
A8XV40, SPAST_CAEBRQ8MNV0, SPAST_CAEELQ5ZK92, SPAST_CHICK
Q6NW58, SPAST_DANREQ54KQ7, SPAST_DICDIB3M301, SPAST_DROAN
B3P8A3, SPAST_DROERB4JII0, SPAST_DROGRQ8I0P1, SPAST_DROME
B4K799, SPAST_DROMOB4G437, SPAST_DROPEQ298L4, SPAST_DROPS
B4HGG6, SPAST_DROSEB4QSF0, SPAST_DROSIB4M0H8, SPAST_DROVI
B4NBP4, SPAST_DROWIB4PL32, SPAST_DROYAQ9UBP0, SPAST_HUMAN
B7PXE3, SPAST_IXOSCQ9QYY8, SPAST_MOUSED2VS83, SPAST_NAEGR
A7T395, SPAST_NEMVEQ719N1, SPAST_PIGB2RYN7, SPAST_RAT
Q6AZT2, SPAST_XENLAQ05AS3, SPAST_XENTR

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-