ENZYME entry: EC 5.6.1.2
| Accepted Name |
|---|
| Dynein ATPase.
|
| Alternative Name(s) |
|---|
| Dynein adenosine 5'-triphosphatase. |
| Reaction catalysed |
|---|
| ATP + H(2)O + a dynein associated with a microtubule at position (n) <=> ADP + phosphate + a dynein associated with a microtubule at position (n-1, toward the minus end) |
| Comment(s) |
|---|
- A multisubunit protein complex associated with microtubules.
- Hydrolysis of ATP provides energy for the movement of organelles
(endosomes, lysosomes, mitochondria) along microtubules to the
centrosome toward the microtubule's minus end.
- It also functions in the movement of eukaryotic flagella and cilia.
- It consists of two heavy chains (about 500 kDa), three-four
intermediate chains (about 70 kDa) and four light chains (about 50
kDa).
- Formerly EC 3.6.1.33 and EC 3.6.4.2.
|
| Cross-references |
|---|
| BRENDA | 5.6.1.2 |
| EC2PDB | 5.6.1.2 |
| ExplorEnz | 5.6.1.2 |
| PRIAM enzyme-specific profiles | 5.6.1.2 |
| KEGG Ligand Database for Enzyme Nomenclature | 5.6.1.2 |
| IUBMB Enzyme Nomenclature | 5.6.1.2 |
| IntEnz | 5.6.1.2 |
| MEDLINE | Find literature relating to 5.6.1.2 |
| MetaCyc | 5.6.1.2 |
| Rhea expert-curated reactions | 5.6.1.2 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 5.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-