ENZYME entry: EC 5.6.1.2
Accepted Name |
Dynein ATPase.
|
Alternative Name(s) |
Dynein adenosine 5'-triphosphatase. |
Reaction catalysed |
ATP + H(2)O + a dynein associated with a microtubule at position (n) <=> ADP + phosphate + a dynein associated with a microtubule at position (n-1, toward the minus end) |
Comment(s) |
- A multisubunit protein complex associated with microtubules.
- Hydrolysis of ATP provides energy for the movement of organelles
(endosomes, lysosomes, mitochondria) along microtubules to the
centrosome toward the microtubule's minus end.
- It also functions in the movement of eukaryotic flagella and cilia.
- It consists of two heavy chains (about 500 kDa), three-four
intermediate chains (about 70 kDa) and four light chains (about 50
kDa).
- Formerly EC 3.6.1.33 AND EC 3.6.4.2.
|
Cross-references |
BRENDA | 5.6.1.2 |
EC2PDB | 5.6.1.2 |
ExplorEnz | 5.6.1.2 |
PRIAM enzyme-specific profiles | 5.6.1.2 |
KEGG Ligand Database for Enzyme Nomenclature | 5.6.1.2 |
IUBMB Enzyme Nomenclature | 5.6.1.2 |
IntEnz | 5.6.1.2 |
MEDLINE | Find literature relating to 5.6.1.2 |
MetaCyc | 5.6.1.2 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 5.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-