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ENZYME entry: EC 6.2.1.15

Accepted Name
Arachidonate--CoA ligase.
Alternative Name(s)
Arachidonoyl-CoA synthetase.
Reaction catalysed
ATP + arachidonate + CoA <=> AMP + diphosphate + arachidonoyl-CoA
Comment(s)
  • 8,11,14-icosatrienoate, but not the other long-chain fatty acids, can act in place of arachidonate.
  • Not identical with EC 6.2.1.3.
Cross-references
BRENDA6.2.1.15
EC2PDB6.2.1.15
ExplorEnz6.2.1.15
PRIAM enzyme-specific profiles6.2.1.15
KEGG Ligand Database for Enzyme Nomenclature6.2.1.15
IUBMB Enzyme Nomenclature6.2.1.15
IntEnz6.2.1.15
MEDLINEFind literature relating to 6.2.1.15
MetaCyc6.2.1.15
UniProtKB/Swiss-Prot
Q5ZKR7, ACBG2_CHICK;  Q5FVE4, ACBG2_HUMAN;  Q2XU92, ACBG2_MOUSE;  
A1L1K7, ACBG2_RAT;  Q7ZYC4, ACBG2_XENLA;  Q9JID6, ACSL1_CAVPO;  
P33121, ACSL1_HUMAN;  P41216, ACSL1_MOUSE;  P18163, ACSL1_RAT;  
O95573, ACSL3_HUMAN;  Q9CZW4, ACSL3_MOUSE;  Q5R668, ACSL3_PONAB;  
Q63151, ACSL3_RAT;  O60488, ACSL4_HUMAN;  Q9QUJ7, ACSL4_MOUSE;  
O35547, ACSL4_RAT;  Q9ULC5, ACSL5_HUMAN;  Q8JZR0, ACSL5_MOUSE;  
O88813, ACSL5_RAT;  Q9UKU0, ACSL6_HUMAN;  Q91WC3, ACSL6_MOUSE;  
P33124, ACSL6_RAT;  Q3ZKN0, S27A1_BOVIN;  Q6PCB7, S27A1_HUMAN;  
Q60714, S27A1_MOUSE;  P97849, S27A1_RAT;  O14975, S27A2_HUMAN;  
O35488, S27A2_MOUSE;  P97524, S27A2_RAT;  Q5K4L6, S27A3_HUMAN;  
O88561, S27A3_MOUSE;  Q6P1M0, S27A4_HUMAN;  Q4R3Y4, S27A4_MACFA;  
Q91VE0, S27A4_MOUSE;  Q5RDY4, S27A4_PONAB;  Q9Y2P4, S27A6_HUMAN;  
E9Q9W4, S27A6_MOUSE;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.1.-
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