ENZYME entry: EC 6.2.1.19
Accepted Name |
Long-chain-fatty-acid--protein ligase.
|
Alternative Name(s) |
Acyl-protein synthetase. |
Reaction catalysed |
ATP + a long-chain fatty acid + [protein]-L-cysteine <=> AMP + diphosphate + a [protein]-S-(long-chain-acyl)-L-cysteine |
Comment(s) |
- Together with a hydrolase component (EC 3.1.2.2/3.1.2.14) and a
reductase component (EC 1.2.1.50), this enzyme forms a multienzyme
fatty acid reductase complex that produces the long-chain aldehyde
substrate of the bacterial luciferase enzyme (EC 1.14.14.3).
- The enzyme activates free long-chain fatty acids, generated by the
action of the transferase component, forming a fatty acyl-AMP
intermediate, followed by the transfer of the acyl group to an
internal L-cysteine residue.
- It then transfers the acyl group to EC 1.2.1.50.
|
Cross-references |
BRENDA | 6.2.1.19 |
EC2PDB | 6.2.1.19 |
ExplorEnz | 6.2.1.19 |
PRIAM enzyme-specific profiles | 6.2.1.19 |
KEGG Ligand Database for Enzyme Nomenclature | 6.2.1.19 |
IUBMB Enzyme Nomenclature | 6.2.1.19 |
IntEnz | 6.2.1.19 |
MEDLINE | Find literature relating to 6.2.1.19 |
MetaCyc | 6.2.1.19 |
UniProtKB/Swiss-Prot |
|
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