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ENZYME

ENZYME entry: EC 6.2.1.35

Accepted Name
acetate--[acyl-carrier protein] ligase
Alternative Name(s)
[acyl-carrier protein]:acetate ligase
ACP-SH:acetate ligase
Reaction catalysed
acetate + ATP + holo-[ACP] = acetyl-[ACP] + AMP + diphosphate
Comment(s)
  • This enzyme, from the anaerobic bacterium Malonomonas rubra, is a component of the multienzyme complex EC 7.2.4.4.
  • The enzyme uses the energy from hydrolysis of ATP to convert the thiol group of the acyl-carrier-protein-bound 2'-(5-phosphoribosyl)- 3'-dephospho-CoA cofactor into its acetyl thioester.
Cross-references
BRENDA6.2.1.35
EC2PDB6.2.1.35
ExplorEnz6.2.1.35
PRIAM enzyme-specific profiles6.2.1.35
KEGG Ligand Database for Enzyme Nomenclature6.2.1.35
IUBMB Enzyme Nomenclature6.2.1.35
IntEnz6.2.1.35
MEDLINEFind literature relating to 6.2.1.35
MetaCyc6.2.1.35
Rhea expert-curated reactions6.2.1.35
UniProtKB/Swiss-Prot
O06928, MADH_MALRU

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