Home  |  Contact

ENZYME entry: EC 6.2.1.44

Accepted Name
3-(methylthio)propionyl--CoA ligase.
Alternative Name(s)
3-methylmercaptopropionyl-CoA ligase.
Methylmercaptopropionate-coenzyme A ligase.
MMPA-CoA ligase.
Reaction catalysed
ATP + 3-(methylthio)propanoate + CoA <=> AMP + diphosphate + 3-(methylthio)propanoyl-CoA
Cofactor(s)
Mg(2+).
Comment(s)
  • The enzyme is part of a dimethylsulfoniopropanoate demethylation pathway in the marine bacteria Ruegeria pomeroyi and Pelagibacter ubique.
  • It also occurs in some nonmarine bacteria capable of metabolizing dimethylsulfoniopropionate (e.g. Burkholderia thailandensis, Pseudomonas aeruginosa, and Silicibacter lacuscaerulensis).
Cross-references
BRENDA6.2.1.44
EC2PDB6.2.1.44
ExplorEnz6.2.1.44
PRIAM enzyme-specific profiles6.2.1.44
KEGG Ligand Database for Enzyme Nomenclature6.2.1.44
IUBMB Enzyme Nomenclature6.2.1.44
IntEnz6.2.1.44
MEDLINEFind literature relating to 6.2.1.44
MetaCyc6.2.1.44
Rhea expert-curated reactions6.2.1.44
UniProtKB/Swiss-Prot
Q5LRT0, DMDB_RUEPO

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-