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ENZYME entry: EC 6.2.1.53

Accepted Name
L-proline--[L-prolyl-carrier protein] ligase.
Reaction catalysed
ATP + L-proline + holo-[L-prolyl-carrier protein] <=> AMP + diphosphate + L-prolyl-[L-prolyl-carrier protein]
Comment(s)
  • The enzyme participates in the biosynthesis of several pyrrole- containing compounds, such as undecylprodigiosin, prodigiosin, pyoluteorin, and coumermycin A1.
  • It catalyzes the activation of L-proline to an adenylate form, followed by its transfer to the 4'-phosphopantheine moiety of an L-prolyl-carrier protein.
Cross-references
BRENDA6.2.1.53
EC2PDB6.2.1.53
ExplorEnz6.2.1.53
PRIAM enzyme-specific profiles6.2.1.53
KEGG Ligand Database for Enzyme Nomenclature6.2.1.53
IUBMB Enzyme Nomenclature6.2.1.53
IntEnz6.2.1.53
MEDLINEFind literature relating to 6.2.1.53
MetaCyc6.2.1.53

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-