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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 6.2.1.53

Accepted Name
L-proline--[L-prolyl-carrier protein] ligase.
Reaction catalysed
ATP + L-proline + holo-[L-prolyl-carrier protein] <=> AMP + diphosphoate + L-prolyl-[L-prolyl-carrier protein]
Comment(s)
  • The enzyme participates in the biosynthesis of several pyrrole- containing compounds, such as undecylprodigiosin, prodigiosin, pyoluteorin, and coumermycin A1.
  • It catalyzes the activation of L-proline to an adenylate form, followed by its transfer to the 4'-phosphopantheine moiety of an L-prolyl-carrier protein.
Cross-references
BRENDA6.2.1.53
EC2PDB6.2.1.53
ExplorEnz6.2.1.53
PRIAM enzyme-specific profiles6.2.1.53
KEGG Ligand Database for Enzyme Nomenclature6.2.1.53
IUBMB Enzyme Nomenclature6.2.1.53
IntEnz6.2.1.53
MEDLINEFind literature relating to 6.2.1.53
MetaCyc6.2.1.53

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-