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ENZYME

ENZYME entry: EC 6.2.1.54

PURL: https://purl.expasy.org/enzyme/EC/6.2.1.54
Accepted Name
D-alanine--[D-alanyl-carrier protein] ligase
Reaction catalysed
holo-[D-alanyl-carrier protein] + D-alanine + ATP = D-alanyl-[D-alanyl-carrier protein] + AMP + diphosphate
Comment(s)
  • The enzyme is involved in the modification of wall teichoic acids, as well as type I and IV lipoteichoic acids, with D-alanine residues.
  • It activates D-alanine using ATP to form a high-energy (D-alanyl)adenylate intermediate and subsequently transfers the alanyl moiety to the phosphopantheinyl tightly-bound cofactor of a D-alanyl-carrier protein (DltC).
Cross-references
BRENDA6.2.1.54
EC2PDB6.2.1.54
ExplorEnz6.2.1.54
KEGG Ligand Database for Enzyme Nomenclature6.2.1.54
IUBMB Enzyme Nomenclature6.2.1.54
MEDLINEFind literature relating to 6.2.1.54
MetaCyc6.2.1.54
Rhea expert-curated reactions6.2.1.54
UniProtKB/Swiss-Prot
A0A5N6TQN5, AVEC_ASPAVJ3KAS2, COCH_COCIMC3P4I7, DLTA_BACAA
C3LAH8, DLTA_BACACA0RBJ0, DLTA_BACAHQ81T97, DLTA_BACAN
B7JFV5, DLTA_BACC0Q73BD2, DLTA_BACC1B7IN64, DLTA_BACC2
C1EM80, DLTA_BACC3B7HHC6, DLTA_BACC4B7HK95, DLTA_BACC7
A7GMR0, DLTA_BACCNB9IUW2, DLTA_BACCQQ81G39, DLTA_BACCR
Q63E02, DLTA_BACCZQ6HLH7, DLTA_BACHKQ65DH1, DLTA_BACLD
A9VKV6, DLTA_BACMKP39581, DLTA_BACSUA7ZA74, DLTA_BACVZ
B3WC77, DLTA_LACCBQ9CG49, DLTA_LACLAQ03AZ2, DLTA_LACP3
Q88VM6, DLTA_LACPLP35854, DLTA_LACRHQ92D47, DLTA_LISIN
C1L1P5, DLTA_LISMCQ721J2, DLTA_LISMFB8DEG2, DLTA_LISMH
Q8Y8D4, DLTA_LISMOA0AH92, DLTA_LISW6A7X0D6, DLTA_STAA1
A6U039, DLTA_STAA2Q2FIE3, DLTA_STAA3Q2FZW6, DLTA_STAA8
A5IRB0, DLTA_STAA9Q2YWQ8, DLTA_STAABQ5HHF2, DLTA_STAAC
A6QFE3, DLTA_STAAEP68876, DLTA_STAAMP99107, DLTA_STAAN
Q6GIF6, DLTA_STAARQ6GAZ4, DLTA_STAASA8Z1J1, DLTA_STAAT
P0C397, DLTA_STAAUP68878, DLTA_STAAWQ5HQN0, DLTA_STAEQ
Q8CT93, DLTA_STAESQ4L4U5, DLTA_STAHJQ9X2N4, DLTA_STAXY
Q3JZ94, DLTA_STRA1Q8VM67, DLTA_STRA3P59591, DLTA_STRA5
C0MBD6, DLTA_STRE4Q53526, DLTA_STRMUQ99ZA6, DLTA_STRP1
Q04HZ7, DLTA_STRP2P0DA64, DLTA_STRP3Q5XBN5, DLTA_STRP6
C1CB20, DLTA_STRP7Q8P0J9, DLTA_STRP8Q1JLB7, DLTA_STRPC
Q1JGF0, DLTA_STRPDQ1J667, DLTA_STRPFA2RE45, DLTA_STRPG
B8ZQ14, DLTA_STRPJQ48SZ3, DLTA_STRPMP0A398, DLTA_STRPN
P0DA65, DLTA_STRPQB5XLX5, DLTA_STRPZP0A399, DLTA_STRR6
C1CNE9, DLTA_STRZPC1CU95, DLTA_STRZTC4JF75, UNCD_UNCRE

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-