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ENZYME

ENZYME entry: EC 6.2.1.69

Accepted Name
L-cysteine--[L-cysteinyl-carrier protein] ligase
Reaction catalysed
ATP + holo-[peptidyl-carrier protein] + L-cysteine <=> AMP + diphosphate + L-cysteinyl-[peptidyl-carrier protein]
Comment(s)
  • The adenylation domain of the enzyme catalyzes the activation of L-cysteine to (L-cysteinyl)adenylate, followed by the transfer of the activated compound to the free thiol of a phosphopantetheine arm of a peptidyl-carrier protein domain.
  • The peptidyl-carrier protein domain may be part of the same protein, or of a different protein.
  • This activity is often found as part of a larger non-ribosomal peptide synthase.
Cross-references
BRENDA6.2.1.69
EC2PDB6.2.1.69
ExplorEnz6.2.1.69
PRIAM enzyme-specific profiles6.2.1.69
KEGG Ligand Database for Enzyme Nomenclature6.2.1.69
IUBMB Enzyme Nomenclature6.2.1.69
IntEnz6.2.1.69
MEDLINEFind literature relating to 6.2.1.69
MetaCyc6.2.1.69
Rhea expert-curated reactions6.2.1.69
UniProtKB/Swiss-Prot
A0A0H2ZGB9, PCHE_PSEABG3XCV2, PCHE_PSEAEA0A0H2ZGJ4, PCHF_PSEAB
Q9HWG4, PCHF_PSEAE

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-