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ENZYME entry: EC 6.2.1.n2

Accepted Name
Amino acid--[acyl-carrier-protein] ligase.
Reaction catalysed
ATP + an amino acid + [acyl-carrier-protein] <=> AMP + diphosphate + an aminoacyl-[acyl-carrier-protein]
Comment(s)
  • Catalyzes the ATP-dependent activation of L-alanine, and to a lesser extent of L-glycine and L-serine, and their transfer to the phosphopantetheine prosthetic group covalently attached to a vicinal carrier protein.
  • May participate in nonribosomal peptide synthesis or related processes.
  • L-proline and L-glutamate are very poor substrates whereas D-amino acids are not substrates for ATP-dependent activation.
  • Does not display tRNA aminoacylation activity.
Cross-references
UniProtKB/Swiss-Prot
Q89VT8, AACL1_BRADU;  Q89GR3, AACL2_BRADU;  Q7CWR3, AACL_AGRFC;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-