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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 7.2.2.12

Accepted Name
P-type Zn(2+) transporter.
Alternative Name(s)
P(1B)-type ATPase.
Zinc-translocating P-type ATPase.
Zn(2+)-exporting ATPase.
Reaction catalysed
ATP + H(2)O + Zn(2+)(Side 1) <=> ADP + phosphate + Zn(2+)(Side 2)
Cofactor(s)
Mg(2+).
Comment(s)
  • A P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • The enzyme, present in prokaryotes and photosynthetic eukaryotes, exports Zn(2+) and the related cations Cd(2+) and Pb(2+).
  • Formerly EC 3.6.3.5.
Cross-references
PROSITEPDOC00139
BRENDA7.2.2.12
EC2PDB7.2.2.12
ExplorEnz7.2.2.12
PRIAM enzyme-specific profiles7.2.2.12
KEGG Ligand Database for Enzyme Nomenclature7.2.2.12
IUBMB Enzyme Nomenclature7.2.2.12
IntEnz7.2.2.12
MEDLINEFind literature relating to 7.2.2.12
MetaCyc7.2.2.12
UniProtKB/Swiss-Prot
Q59998, ATZN_SYNY3;  O32219, CADA_BACSU;  Q9M3H5, HMA1_ARATH;  
Q9SZW4, HMA2_ARATH;  A3BF39, HMA2_ORYSJ;  P0CW78, HMA3B_ARATH;  
Q8H384, HMA3_ORYSJ;  O64474, HMA4_ARATH;  Q9RQB4, HMCT_HELFE;  
Q9ZL53, HMCT_HELPJ;  Q59465, HMCT_HELPY;  P37617, ZNTA_ECOLI;  
Q3YW59, ZNTA_SHISS;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.2.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.-.-.-