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ENZYME entry: EC 7.2.2.8

Accepted Name
P-type Cu(+) transporter.
Alternative Name(s)
Cu(+)-exporting ATPase.
Reaction catalysed
ATP + Cu(+)(in) + H2O <=> ADP + Cu(+)(out) + H(+) + phosphate
Comment(s)
  • A P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • This enzyme transports Cu(+) or Ag(+), and cannot transport the divalent ions, contrary to EC 7.2.2.9, which mainly transports the divalent copper ion.
  • Formerly EC 3.6.3.54 and EC 3.6.3.n1.
Cross-references
BRENDA7.2.2.8
EC2PDB7.2.2.8
ExplorEnz7.2.2.8
PRIAM enzyme-specific profiles7.2.2.8
KEGG Ligand Database for Enzyme Nomenclature7.2.2.8
IUBMB Enzyme Nomenclature7.2.2.8
IntEnz7.2.2.8
MEDLINEFind literature relating to 7.2.2.8
MetaCyc7.2.2.8
Rhea expert-curated reactions7.2.2.8
UniProtKB/Swiss-Prot
P37279, ATCS_SYNE7;  P73241, ATCS_SYNY3;  P49015, ATP7A_CRIGR;  
Q04656, ATP7A_HUMAN;  Q64430, ATP7A_MOUSE;  P70705, ATP7A_RAT;  
P35670, ATP7B_HUMAN;  Q64446, ATP7B_MOUSE;  Q64535, ATP7B_RAT;  
Q9XT50, ATP7B_SHEEP;  P37385, ATSY_SYNE7;  O59666, ATU2_SCHPO;  
P38995, ATU2_YEAST;  O29777, COPA_ARCFU;  O32220, COPA_BACSU;  
Q8XD24, COPA_ECO57;  Q59385, COPA_ECOLI;  P32113, COPA_ENTHA;  
O32619, COPA_HELFC;  Q5ZWR1, COPA_LEGPH;  Q8Z8S4, COPA_SALTI;  
Q8ZR95, COPA_SALTY;  A7X6S1, COPA_STAA1;  A6U4T8, COPA_STAA2;  
Q2FDV0, COPA_STAA3;  Q2FV64, COPA_STAA8;  A5IVY3, COPA_STAA9;  
Q2YWA3, COPA_STAAB;  Q5HCZ3, COPA_STAAC;  A6QK47, COPA_STAAE;  
Q99R80, COPA_STAAM;  Q7A3E6, COPA_STAAN;  Q6GDP1, COPA_STAAR;  
Q6G6B7, COPA_STAAS;  A8Z3F8, COPA_STAAT;  Q8NUQ9, COPA_STAAW;  
Q5HL56, COPA_STAEQ;  Q8CN02, COPA_STAES;  Q4L970, COPA_STAHJ;  
Q4A0G1, COPA_STAS1;  Q9KPZ7, COPA_VIBCH;  Q8ZCA7, COPA_YERPE;  
P05425, COPB_ENTHA;  Q2FKI2, COPB_STAA3;  Q6GIX4, COPB_STAAR;  
A8YZ02, COPB_STAAT;  Q69HU0, COPB_STAAU;  Q5HKB0, COPB_STAEQ;  
Q8CQF7, COPB_STAES;  Q4LAB1, COPB_STAHJ;  P46839, CTPA_MYCLE;  
P9WPU0, CTPA_MYCTO;  P9WPU1, CTPA_MYCTU;  P9WPS2, CTPV_MYCTO;  
P9WPS3, CTPV_MYCTU;  Q6H7M3, HMA4_ORYSJ;  Q9SH30, HMA5_ARATH;  
A3AWA4, HMA5_ORYSJ;  Q9SZC9, HMA6_ARATH;  Q9S7J8, HMA7_ARATH;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.2.2.-
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