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ENZYME

ENZYME entry: EC 7.2.3.1

PURL: https://purl.expasy.org/enzyme/EC/7.2.3.1
Accepted Name
Na(+)-exporting diphosphatase
Alternative Name(s)
Na(+)-translocating membrane pyrophosphatase
sodium-translocating pyrophosphatase
Reaction catalysed
Na(+)(in) + diphosphate + H2O = Na(+)(out) + 2 phosphate + H(+)
Comment(s)
  • Requires Na(+) and K(+).
  • This enzyme, found in some bacteria and archaea, couples the energy from diphosphate hydrolysis to active sodium translocation across the membrane.
  • The enzyme is electrogenic, as the Na(+) transport results in generation of a positive potential in the inner side of the membrane.
  • Formerly EC 7.1.3.2.
Cross-references
BRENDA7.2.3.1
EC2PDB7.2.3.1
ExplorEnz7.2.3.1
KEGG Ligand Database for Enzyme Nomenclature7.2.3.1
IUBMB Enzyme Nomenclature7.2.3.1
MEDLINEFind literature relating to 7.2.3.1
MetaCyc7.2.3.1
Rhea expert-curated reactions7.2.3.1
UniProtKB/Swiss-Prot
Q8TJA9, HPPA1_METACQ8PYZ8, HPPA1_METMAQ2RIS7, HPPA1_MOOTA
Q8VPZ0, HPPA_AGRTUQ8A294, HPPA_BACTNQ898Q9, HPPA_CLOTE
Q8RHJ2, HPPA_FUSNNQ8VNJ8, HPPA_HELCLQ72Q29, HPPA_LEPIC
Q8F641, HPPA_LEPINQ93NB7, HPPA_MYXXAQ9S5X0, HPPA_THEMA

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.2.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.-.-.-