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ENZYME

ENZYME entry: EC 7.2.4.2

PURL: https://purl.expasy.org/enzyme/EC/7.2.4.2
Accepted Name
oxaloacetate decarboxylase (Na(+) extruding)
Alternative Name(s)
oxalacetic acid decarboxylase
oxalate beta-decarboxylase
oxaloacetate beta-decarboxylase
Reaction catalysed
oxaloacetate + 2 Na(+)(in) + H(+) = pyruvate + 2 Na(+)(out) + CO2
Comment(s)
  • The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.
  • The process is accompanied by the extrusion of two sodium ions from cells.
  • Some animal enzymes require Mn(2+).
  • Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.
  • Formerly EC 4.1.1.3.
Cross-references
BRENDA7.2.4.2
EC2PDB7.2.4.2
ExplorEnz7.2.4.2
KEGG Ligand Database for Enzyme Nomenclature7.2.4.2
IUBMB Enzyme Nomenclature7.2.4.2
MEDLINEFind literature relating to 7.2.4.2
MetaCyc7.2.4.2
Rhea expert-curated reactions7.2.4.2
UniProtKB/Swiss-Prot
P13187, DCOA_KLEPNQ8XGX8, DCOA_SALTIQ03030, DCOA_SALTY
Q8Z9M6, OADB1_SALTIQ8ZRY4, OADB1_SALTYQ8Z3E5, OADB2_SALTI
Q03031, OADB2_SALTYQ9RF98, OADB_HAEDUP13156, OADB_KLEPN
Q9CL24, OADB_PASMUQ9KTU5, OADB_VIBCHQ5PKI8, OADG1_SALPA
Q8Z9M5, OADG1_SALTIP58651, OADG1_SALTYQ9KUH2, OADG1_VIBCH
Q5PJT2, OADG2_SALPAQ8Z3E4, OADG2_SALTIQ03032, OADG2_SALTY
Q9KTU4, OADG2_VIBCHP58650, OADG3_SALTYA3N223, OADG_ACTP2
B3GYF4, OADG_ACTP7A6VL34, OADG_ACTSZB7LVP2, OADG_ESCF3
Q9RFA0, OADG_HAEDUA6T4H1, OADG_KLEP7P13155, OADG_KLEPN
Q65WL3, OADG_MANSMQ9CL26, OADG_PASMUB5F736, OADG_SALA4
A9MYH6, OADG_SALPBQ87LR6, OADG_VIBPAQ8DC44, OADG_VIBVU
Q7MHR9, OADG_VIBVY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.2.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.-.-.-