Expasy logo

ENZYME

ENZYME entry: EC 7.2.4.2

PURL: https://purl.expasy.org/enzyme/EC/7.2.4.2
Accepted Name
oxaloacetate decarboxylase (Na(+) extruding)
Alternative Name(s)
oxalacetic acid decarboxylase
oxalate beta-decarboxylase
oxaloacetate beta-decarboxylase
Reaction catalysed
oxaloacetate + 2 Na(+)(in) + H(+) = pyruvate + 2 Na(+)(out) + CO2
Comment(s)
  • The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.
  • The process is accompanied by the extrusion of two sodium ions from cells.
  • Some animal enzymes require Mn(2+).
  • Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.
  • Formerly EC 4.1.1.3.
Cross-references
Rhea expert-curated reactions7.2.4.2
ExplorEnz7.2.4.2
IUBMB Enzyme Nomenclature7.2.4.2
UniProtKB/Swiss-Prot
P13187, DCOA_KLEPNQ8XGX8, DCOA_SALTIQ03030, DCOA_SALTY
Q8Z9M6, OADB1_SALTIQ8ZRY4, OADB1_SALTYQ8Z3E5, OADB2_SALTI
Q03031, OADB2_SALTYQ9RF98, OADB_HAEDUP13156, OADB_KLEPN
Q9CL24, OADB_PASMUQ9KTU5, OADB_VIBCHQ5PKI8, OADG1_SALPA
Q8Z9M5, OADG1_SALTIP58651, OADG1_SALTYQ9KUH2, OADG1_VIBCH
Q5PJT2, OADG2_SALPAQ8Z3E4, OADG2_SALTIQ03032, OADG2_SALTY
Q9KTU4, OADG2_VIBCHP58650, OADG3_SALTYA3N223, OADG_ACTP2
B3GYF4, OADG_ACTP7A6VL34, OADG_ACTSZB7LVP2, OADG_ESCF3
Q9RFA0, OADG_HAEDUA6T4H1, OADG_KLEP7P13155, OADG_KLEPN
Q65WL3, OADG_MANSMQ9CL26, OADG_PASMUB5F736, OADG_SALA4
A9MYH6, OADG_SALPBQ87LR6, OADG_VIBPAQ8DC44, OADG_VIBVU
Q7MHR9, OADG_VIBVY
BRENDA7.2.4.2
MetaCyc7.2.4.2
KEGG Ligand Database for Enzyme Nomenclature7.2.4.2
EC2PDB7.2.4.2
MEDLINEFind literature relating to 7.2.4.2

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.2.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 7.-.-.-