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ENZYME entry: EC 188.8.131.52
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|Sterol 4-alpha-carboxylic decarboxylase.|
|Sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating).|
|A 3-beta-hydroxysteroid-4-alpha-carboxylate + NAD(P)(+) <=> a 3-oxosteroid + CO(2) + NAD(P)H|
- The enzyme catalyzes the decarboxylation of the C-4 carbon and the
dehydrogenation of a 3-beta hydroxyl at the C-3 carbon of 3-beta-
- It is involved in zymosterol and cholesterol biosynthesis.
|PRIAM enzyme-specific profiles||184.108.40.206|
|KEGG Ligand Database for Enzyme Nomenclature||220.127.116.11|
|IUBMB Enzyme Nomenclature||18.104.22.168|
|MEDLINE||Find literature relating to 22.214.171.124|
|O43050, ERG26_SCHPO; ||P53199, ERG26_YEAST; ||Q9FX01, HSDD1_ARATH; |
|Q67ZE1, HSDD2_ARATH; ||A9X4U2, HSDD3_ARATH; ||Q3ZBE9, NSDHL_BOVIN; |
|Q54L85, NSDHL_DICDI; ||Q15738, NSDHL_HUMAN; ||Q9R1J0, NSDHL_MOUSE; |
|Q5PPL3, NSDHL_RAT; |
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entries corresponding to 1.1.1.-
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