ENZYME entry: EC 1.1.1.268

Accepted Name
2-(R)-hydroxypropyl-CoM dehydrogenase.
Alternative Name(s)
2-(2-(R)-hydroxypropylthio)ethanesulfonate dehydrogenase.
Reaction catalysed
2-(R)-hydroxypropyl-CoM + NAD(+) <=> 2-oxopropyl-CoM + NADH
Comment(s)
  • Highly specific for (R)-2-hydroxyalkyl thioethers of CoM, in contrast to EC 1.1.1.269, which is highly specific for the (S)-enantiomer.
  • Forms component III of a four-component enzyme system (comprising EC 4.4.1.23 (component I), EC 1.8.1.5 (component II), EC 1.1.1.268 (component III) and EC 1.1.1.269 (component IV)) that is involved in epoxyalkane carboxylation in Xanthobacter sp. strain Py2.
Cross-references
BRENDA1.1.1.268
EC2PDB1.1.1.268
ExplorEnz1.1.1.268
PRIAM enzyme-specific profiles1.1.1.268
KEGG Ligand Database for Enzyme Nomenclature1.1.1.268
IUBMB Enzyme Nomenclature1.1.1.268
IntEnz1.1.1.268
MEDLINEFind literature relating to 1.1.1.268
MetaCyc1.1.1.268
UniProtKB/Swiss-Prot
Q56840, HCDR_XANP2

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