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ENZYME entry: EC 1.1.1.351

Accepted Name
Phosphogluconate dehydrogenase (NAD(P)(+)-dependent, decarboxylating).
Reaction catalysed
6-phospho-D-gluconate + NAD(P)(+) <=> D-ribulose 5-phosphate + CO(2) + NAD(P)H
Comment(s)
  • The enzyme participates in the oxidative branch of the pentose phosphate pathway, whose main purpose is to produce reducing power and pentose for biosynthetic reactions.
  • Unlike EC 1.1.1.44, it is not specific for NADP(+) and can accept both cofactors with similar efficiency.
  • Cf. EC 1.1.1.343.
Cross-references
BRENDA1.1.1.351
EC2PDB1.1.1.351
ExplorEnz1.1.1.351
PRIAM enzyme-specific profiles1.1.1.351
KEGG Ligand Database for Enzyme Nomenclature1.1.1.351
IUBMB Enzyme Nomenclature1.1.1.351
IntEnz1.1.1.351
MEDLINEFind literature relating to 1.1.1.351
MetaCyc1.1.1.351

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-