Due to scheduled maintenance work, this service may not be available on Monday January 22nd between 08.00 am and 9.00 am CEST.
To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https

ENZYME entry: EC 1.2.1.10

Accepted Name
Acetaldehyde dehydrogenase (acetylating).
Alternative Name(s)
Acylating acetaldehyde dehydrogenase.
Aldehyde dehydrogenase (acylating).
Reaction catalysed
Acetaldehyde + CoA + NAD(+) <=> acetyl-CoA + NADH
Comment(s)
  • Also acts, more slowly, on glycolaldehyde, propanal and butanal.
  • In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.
  • The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.
  • Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.
  • NADP(+) can replace NAD(+) but the rate of reaction is much slower.
Cross-references
PROSITEPDOC00059
BRENDA1.2.1.10
EC2PDB1.2.1.10
ExplorEnz1.2.1.10
PRIAM enzyme-specific profiles1.2.1.10
KEGG Ligand Database for Enzyme Nomenclature1.2.1.10
IUBMB Enzyme Nomenclature1.2.1.10
IntEnz1.2.1.10
MEDLINEFind literature relating to 1.2.1.10
MetaCyc1.2.1.10
UniProtKB/Swiss-Prot
A1K6L8, ACDH1_AZOSB;  C1DMT1, ACDH1_AZOVD;  B4EK77, ACDH1_BURCJ;  
Q397R0, ACDH1_BURL3;  A4JPX8, ACDH1_BURVG;  Q83VZ4, ACDH1_COMTE;  
Q1LNS3, ACDH1_CUPMC;  Q0K3S6, ACDH1_CUPNH;  Q47HL9, ACDH1_DECAR;  
A8LAA2, ACDH1_FRASN;  A2SI34, ACDH1_METPP;  B1MH39, ACDH1_MYCA9;  
B2HGH0, ACDH1_MYCMM;  A0QZU1, ACDH1_MYCS2;  A3Q4B8, ACDH1_MYCSJ;  
A1UM81, ACDH1_MYCSK;  Q1B2X0, ACDH1_MYCSS;  A0PR19, ACDH1_MYCUA;  
Q5Z2N3, ACDH1_NOCFA;  A1SH78, ACDH1_NOCSJ;  A4XF36, ACDH1_NOVAD;  
B2JLM7, ACDH1_PARP8;  Q143P8, ACDH1_PARXL;  A5W4E5, ACDH1_PSEP1;  
Q4F8I0, ACDH1_PSEPS;  B1J6Y6, ACDH1_PSEPW;  C0ZPX0, ACDH1_RHOE4;  
Q0SJD4, ACDH1_RHOJR;  C1B7L1, ACDH1_RHOOB;  A8M1N1, ACDH1_SALAI;  
A5V6T7, ACDH1_SPHWW;  A1K6Y5, ACDH2_AZOSB;  C1DRI9, ACDH2_AZOVD;  
B4EFI8, ACDH2_BURCJ;  Q396N9, ACDH2_BURL3;  A4JW24, ACDH2_BURVG;  
Q9RHN2, ACDH2_COMTE;  Q1LCQ9, ACDH2_CUPMC;  Q0K3N1, ACDH2_CUPNH;  
Q47GC7, ACDH2_DECAR;  A8LEP9, ACDH2_FRASN;  A2SL36, ACDH2_METPP;  
B1MJT8, ACDH2_MYCA9;  B2HI26, ACDH2_MYCMM;  A0R4S7, ACDH2_MYCS2;  
A3Q6N0, ACDH2_MYCSJ;  A1UQA0, ACDH2_MYCSK;  Q1B0P7, ACDH2_MYCSS;  
A0PUX3, ACDH2_MYCUA;  A1TDB8, ACDH2_MYCVP;  Q5YV94, ACDH2_NOCFA;  
A1SIM4, ACDH2_NOCSJ;  A4XDT7, ACDH2_NOVAD;  B2JQV9, ACDH2_PARP8;  
Q13VU2, ACDH2_PARXL;  A5W4F9, ACDH2_PSEP1;  Q52039, ACDH2_PSEPS;  
B1J6Y2, ACDH2_PSEPW;  C0ZU49, ACDH2_RHOE4;  Q0S9X0, ACDH2_RHOJR;  
C1B8H9, ACDH2_RHOOB;  A8M6W7, ACDH2_SALAI;  C1DN56, ACDH3_AZOVD;  
Q390P5, ACDH3_BURL3;  Q9S153, ACDH3_COMTE;  Q47B12, ACDH3_DECAR;  
A1TFQ6, ACDH3_MYCVP;  Q5YUH5, ACDH3_NOCFA;  Q13QH7, ACDH3_PARXL;  
Q0S816, ACDH3_RHOJR;  C1BAJ3, ACDH3_RHOOB;  A5VGU5, ACDH3_SPHWW;  
C1DF11, ACDH4_AZOVD;  Q39LH7, ACDH4_BURL3;  Q479G9, ACDH4_DECAR;  
Q79AF6, ACDH4_PARXL;  Q0S4F9, ACDH4_RHOJR;  C1AVG3, ACDH4_RHOOB;  
Q479E6, ACDH5_DECAR;  Q0S005, ACDH5_RHOJR;  C1AYB3, ACDH5_RHOOB;  
Q0RXC4, ACDH6_RHOJR;  C1BE29, ACDH6_RHOOB;  Q0RWM7, ACDH7_RHOJR;  
A1W2K2, ACDH_ACISJ;  B9JML7, ACDH_AGRRK;  Q0A5T6, ACDH_ALKEH;  
A0RD69, ACDH_BACAH;  Q739I5, ACDH_BACC1;  C1ERL6, ACDH_BACC3;  
Q764S1, ACDH_BACPJ;  Q2KXU8, ACDH_BORA1;  C0ZDU5, ACDH_BREBN;  
Q2VLC6, ACDH_BURCE;  A3P826, ACDH_BURP0;  Q3JK54, ACDH_BURP1;  
A3NML3, ACDH_BURP6;  Q63JB0, ACDH_BURPS;  Q2T7T0, ACDH_BURTA;  
Q3ACM1, ACDH_CARHZ;  A9W9U2, ACDH_CHLAA;  B8GBV4, ACDH_CHLAD;  
B9LCM0, ACDH_CHLSY;  Q46NW7, ACDH_CUPNJ;  B2AIJ6, ACDH_CUPTR;  
B8G186, ACDH_DESHD;  A7ZI98, ACDH_ECO24;  B7L507, ACDH_ECO55;  
Q8X5J9, ACDH_ECO57;  B5Z2Q6, ACDH_ECO5E;  B7NK04, ACDH_ECO7I;  
B7MPB8, ACDH_ECO81;  B7M2Z9, ACDH_ECO8A;  C4ZTB5, ACDH_ECOBW;  
A7ZWZ8, ACDH_ECOHS;  B1J0S8, ACDH_ECOLC;  P77580, ACDH_ECOLI;  
B7N8Q8, ACDH_ECOLU;  B6HZX7, ACDH_ECOSE;  B1LIN6, ACDH_ECOSM;  
B0VXM6, ACDH_GEOSE;  A4IT43, ACDH_GEOTN;  B5XQJ3, ACDH_KLEP3;  
A6TAC5, ACDH_KLEP7;  B1Y2E6, ACDH_LEPCP;  A6W1X2, ACDH_MARMS;  
B8ESV1, ACDH_METSB;  Q2RHL2, ACDH_MOOTA;  A0QAG8, ACDH_MYCA1;  
Q7TTR4, ACDH_MYCBO;  A1KPM0, ACDH_MYCBP;  C1AHZ3, ACDH_MYCBT;  
A4T7U3, ACDH_MYCGI;  Q743Q9, ACDH_MYCPA;  A5U8K9, ACDH_MYCTA;  
P9WQH2, ACDH_MYCTO;  P9WQH3, ACDH_MYCTU;  O85978, ACDH_NOVAR;  
B2T2S1, ACDH_PARPJ;  Q6D797, ACDH_PECAS;  A5D522, ACDH_PELTS;  
A1VUV2, ACDH_POLNA;  Q120P0, ACDH_POLSJ;  Q3IEN6, ACDH_PSEHT;  
Q49KG0, ACDH_PSEPU;  Q9KWS1, ACDH_PSESP;  Q9ZI57, ACDH_PSEST;  
Q52060, ACDH_PSEUF;  B2UJF2, ACDH_RALPJ;  Q8XRG0, ACDH_RALSO;  
Q221U6, ACDH_RHOFT;  A7NLU3, ACDH_ROSCS;  A5UWE5, ACDH_ROSS1;  
A4XAK8, ACDH_SALTO;  B0TTT0, ACDH_SHEHH;  A8H4F0, ACDH_SHEPA;  
B1KJL0, ACDH_SHEWM;  Q3Z555, ACDH_SHISS;  A2TC44, ACDH_SPHYA;  
Q0PHY0, ACDH_SPIAU;  B1VRH6, ACDH_STRGG;  B9L2J1, ACDH_THERP;  
Q53WH9, ACDH_THET8;  A1WLL3, ACDH_VEREI;  A7IDU5, ACDH_XANP2;  
Q24803, ADH2_ENTHI;  P0A9Q8, ADHE_ECO57;  P0A9Q7, ADHE_ECOLI;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-