ENZYME entry: EC 1.2.1.87

Accepted Name
Propanal dehydrogenase (CoA-propanoylating).
Reaction catalysed
Propanal + CoA + NAD(+) <=> propanoyl-CoA + NADH
Comment(s)
  • The enzyme forms a bifunctional complex with EC 4.1.3.43, with a tight channel connecting the two subunits.
  • Also acts, more slowly, on glycolaldehyde and butanal.
  • In Pseudomonas species the enzyme forms a bifunctional complex with EC 4.1.3.39.
  • The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.10.
  • NADP(+) can replace NAD(+) with a much slower rate.
Cross-references
BRENDA1.2.1.87
EC2PDB1.2.1.87
ExplorEnz1.2.1.87
PRIAM enzyme-specific profiles1.2.1.87
KEGG Ligand Database for Enzyme Nomenclature1.2.1.87
IUBMB Enzyme Nomenclature1.2.1.87
IntEnz1.2.1.87
MEDLINEFind literature relating to 1.2.1.87
MetaCyc1.2.1.87
UniProtKB/Swiss-Prot
Q79AF6, ACDH4_BURXL;  Q53WH9, ACDH_THET8;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-