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ENZYME entry: EC

Accepted Name
2-oxoglutarate synthase.
Alternative Name(s)
2-ketoglutarate ferredoxin oxidoreductase.
2-oxoglutarate ferredoxin oxidoreductase.
Alpha-ketoglutarate synthase.
Alpha-ketoglutarate-ferredoxin oxidoreductase.
Reaction catalysed
2-oxoglutarate + CoA + 2 oxidized ferredoxin <=> succinyl-CoA + CO(2) + 2 reduced ferredoxin + 2 H(+)
Iron-sulfur; Thiamine diphosphate.
  • Highly specific for 2-oxoglutarate.
  • This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.
  • For examples of other members of this family, see EC and EC
  • Formerly EC
PRIAM enzyme-specific profiles1.2.7.3
KEGG Ligand Database for Enzyme Nomenclature1.2.7.3
IUBMB Enzyme Nomenclature1.2.7.3
MEDLINEFind literature relating to
O29781, KORA_ARCFU;  Q57724, KORA_METJA;  O27112, KORA_METTH;  
P80904, KORA_METTM;  O53182, KORA_MYCTU;  O29782, KORB_ARCFU;  
Q57957, KORB_METJA;  O27113, KORB_METTH;  P80905, KORB_METTM;  
O53181, KORB_MYCTU;  O29779, KORC_ARCFU;  Q57956, KORC_METJA;  
O27114, KORC_METTH;  P80906, KORC_METTM;  

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