ENZYME entry: EC 1.2.7.3
| Accepted Name |
|---|
| 2-oxoglutarate synthase.
|
| Alternative Name(s) |
|---|
| 2-ketoglutarate ferredoxin oxidoreductase. |
| 2-oxoglutarate ferredoxin oxidoreductase. |
| Alpha-ketoglutarate synthase. |
| Alpha-ketoglutarate-ferredoxin oxidoreductase. |
| KGOR. |
| Reaction catalysed |
|---|
| 2-oxoglutarate + CoA + 2 oxidized ferredoxin <=> succinyl-CoA + CO(2) + 2 reduced ferredoxin + 2 H(+) |
| Cofactor(s) |
|---|
| Iron-sulfur; Thiamine diphosphate.
|
| Comment(s) |
|---|
- One of four 2-oxoacid oxidoreductases that are differentiated by
their abilities to oxidatively decarboxylate different 2-oxoacids and
form their CoA derivatives (see also EC 1.2.7.1, EC 1.2.7.7 and
EC 1.2.7.8).
- Highly specific for 2-oxoglutarate.
- Formerly EC 1.2.7.9.
|
| Cross-references |
|---|
| BRENDA | 1.2.7.3 |
| EC2PDB | 1.2.7.3 |
| ExplorEnz | 1.2.7.3 |
| PRIAM enzyme-specific profiles | 1.2.7.3 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.2.7.3 |
| IUBMB Enzyme Nomenclature | 1.2.7.3 |
| IntEnz | 1.2.7.3 |
| MEDLINE | Find literature relating to 1.2.7.3 |
| MetaCyc | 1.2.7.3 |
| UniProtKB/Swiss-Prot |
| O29781, KORA_ARCFU; | Q57724, KORA_METJA; | O27112, KORA_METTH; |
| P80904, KORA_METTM; | O29782, KORB_ARCFU; | Q57957, KORB_METJA; |
| O27113, KORB_METTH; | P80905, KORB_METTM; | O29779, KORC_ARCFU; |
| Q57956, KORC_METJA; | O27114, KORC_METTH; | P80906, KORC_METTM; |
|
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