ENZYME entry: EC 1.3.1.15

Accepted Name
Dihydroorotate dehydrogenase (NADP(+)).
Reaction catalysed
(S)-dihydroorotate + NADP(+) <=> orotate + NADPH
Cofactor(s)
FAD; FMN.
Comment(s)
  • Other class 1 dihydroorotate dehydrogenases use either fumarate (EC 1.3.98.1) or NAD(+) (EC 1.3.1.14) as electron acceptor.
  • The membrane bound class 2 dihydroorotate dehydrogenase (EC 1.3.5.2) uses quinone as electron acceptor.
Cross-references
BRENDA1.3.1.15
EC2PDB1.3.1.15
ExplorEnz1.3.1.15
PRIAM enzyme-specific profiles1.3.1.15
KEGG Ligand Database for Enzyme Nomenclature1.3.1.15
IUBMB Enzyme Nomenclature1.3.1.15
IntEnz1.3.1.15
MEDLINEFind literature relating to 1.3.1.15
MetaCyc1.3.1.15

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