ENZYME entry: EC 188.8.131.52
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|Short-chain acyl-CoA dehydrogenase.
|Short-chain acyl CoA dehydrogenase.|
|Unsaturated acyl-CoA reductase.|
|A short-chain acyl-CoA + electron-transfer flavoprotein <=> a short-chain trans-2,3-dehydroacyl-CoA + reduced electron-transfer flavoprotein|
- One of several enzymes that catalyze the first step in fatty acids
- The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA
thioesters to give a trans 2,3-unsaturated product by removal of the
two pro-R-hydrogen atoms.
- The enzyme from beef liver accepts substrates with acyl chain lengths
of 3 to 8 carbon atoms.
- The highest activity was reported with either butanoyl-CoA or
- The enzyme from rat has only 10% activity with hexanoyl-CoA (compared
to butanoyl-CoA) and no activity with octanoyl-CoA.
- Cf. EC 184.108.40.206, EC 220.127.116.11 and EC 18.104.22.168.
- Formerly EC 22.214.171.124 and EC 126.96.36.199.
|PRIAM enzyme-specific profiles||188.8.131.52|
|KEGG Ligand Database for Enzyme Nomenclature||184.108.40.206|
|IUBMB Enzyme Nomenclature||220.127.116.11|
|MEDLINE||Find literature relating to 18.104.22.168|
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