ENZYME entry: EC 1.5.1.47

Accepted Name
Dihydromethanopterin reductase (NAD(P)(+)).
Alternative Name(s)
5,6,7,8-tetrahydromethanopterin 5,6-oxidoreductase.
Dihydromethanopterin reductase.
H(2)MPT reductase.
Reaction catalysed
5,6,7,8-tetrahydromethanopterin + NAD(P)(+) <=> 7,8-dihydromethanopterin + NAD(P)H
Comment(s)
  • The enzyme, characterized from the bacterium Methylobacterium extorquens, is involved in biosynthesis of dephospho- tetrahydromethanopterin.
  • The specific activity with NADH is 15% of that with NADPH at the same concentration.
  • It does not reduce 7,8-dihydrofolate (cf. EC 1.5.1.3).
Cross-references
BRENDA1.5.1.47
EC2PDB1.5.1.47
ExplorEnz1.5.1.47
PRIAM enzyme-specific profiles1.5.1.47
KEGG Ligand Database for Enzyme Nomenclature1.5.1.47
IUBMB Enzyme Nomenclature1.5.1.47
IntEnz1.5.1.47
MEDLINEFind literature relating to 1.5.1.47
MetaCyc1.5.1.47
UniProtKB/Swiss-Prot
C5B2R8, DMRA_METEA

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.5.1.-
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