ENZYME entry: EC 2.1.1.101

Accepted Name
Macrocin O-methyltransferase.
Alternative Name(s)
MOMT.
Reaction catalysed
S-adenosyl-L-methionine + macrocin <=> S-adenosyl-L-homocysteine + tylosin
Cofactor(s)
Mg(2+).
Comment(s)
  • The 3-hydroxyl group of a 2-O-methyl-6-deoxy-D-allose residue in the macrolide antibiotic macrocin acts as methyl acceptor.
  • Isolated from Streptomyces fradiae.
  • Tylosin is a macrolide antibiotic.
  • Not identical with EC 2.1.1.102.
Cross-references
BRENDA2.1.1.101
EC2PDB2.1.1.101
ExplorEnz2.1.1.101
PRIAM enzyme-specific profiles2.1.1.101
KEGG Ligand Database for Enzyme Nomenclature2.1.1.101
IUBMB Enzyme Nomenclature2.1.1.101
IntEnz2.1.1.101
MEDLINEFind literature relating to 2.1.1.101
MetaCyc2.1.1.101
UniProtKB/Swiss-Prot
Q9S4D5, TYLF_STRFR

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