ENZYME entry: EC 2.1.1.192

Accepted Name
23S rRNA (adenine(2503)-C(2))-methyltransferase.
Reaction catalysed
  • 2 S-adenosyl-L-methionine + adenine(2503) in 23S rRNA + 2 reduced [2Fe-2S] ferredoxin <=> S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + 2-methyladenine(2503) in 23S rRNA + 2 oxidized [2Fe-2S] ferredoxin
  • 2 S-adenosyl-L-methionine + adenine(37) in tRNA + 2 reduced [2Fe-2S] ferredoxin <=> S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + 2-methyladenine(37) in tRNA + 2 oxidized [2Fe-2S] ferredoxin
Cofactor(s)
Iron-sulfur.
Comment(s)
  • This enzyme is a member of the 'AdoMet radical' (radical SAM) family.
  • S-adenosyl-L-methionine acts as both a radical generator and as the source of the appended methyl group.
  • RlmN first transfers an CH(2) group to a conserved cysteine (Cys(355) in Escherichia coli), the generated radical from a second S-adenosyl- L-methionine then attacks the methyl group, exctracting a hydrogen.
  • The formed radical forms a covalent intermediate with the adenine group of the tRNA.
  • RlmN is an endogenous enzyme used by the cell to refine functions of the ribosome in protein synthesis.
  • The enzyme methylates adenosine by a radical mechanism with CH(2) from the S-adenosyl-L-methionine and retention of the hydrogen at C-2 of adenosine(2503) of 23S rRNA.
  • It will also methylate 8-methyladenosine(2503) of 23S rRNA (cf. EC 2.1.1.224).
Cross-references
BRENDA2.1.1.192
EC2PDB2.1.1.192
ExplorEnz2.1.1.192
PRIAM enzyme-specific profiles2.1.1.192
KEGG Ligand Database for Enzyme Nomenclature2.1.1.192
IUBMB Enzyme Nomenclature2.1.1.192
IntEnz2.1.1.192
MEDLINEFind literature relating to 2.1.1.192
MetaCyc2.1.1.192
UniProtKB/Swiss-Prot
Q1DCU1, RLMN1_MYXXD;  B1ZQZ5, RLMN1_OPITP;  Q6MED6, RLMN1_PARUW;  
Q1D6I6, RLMN2_MYXXD;  B1ZVM5, RLMN2_OPITP;  Q6MDD0, RLMN2_PARUW;  
B2A0B9, RLMN3_OPITP;  B0C9F4, RLMN_ACAM1;  A9NEU7, RLMN_ACHLI;  
A1TM24, RLMN_ACIAC;  Q6FEM6, RLMN_ACIAD;  B7H072, RLMN_ACIB3;  
B7I5G4, RLMN_ACIB5;  B2I3E2, RLMN_ACIBC;  B0VKS2, RLMN_ACIBS;  
A3M208, RLMN_ACIBT;  B0V4U0, RLMN_ACIBY;  A0LV48, RLMN_ACIC1;  
A5G209, RLMN_ACICJ;  A1W574, RLMN_ACISJ;  A3N1S4, RLMN_ACTP2;  
B0BQK6, RLMN_ACTPJ;  A6VQX9, RLMN_ACTSZ;  A0KJ41, RLMN_AERHH;  
A4SP04, RLMN_AERS4;  Q7CWI1, RLMN_AGRFC;  B9JCI9, RLMN_AGRRK;  
B9JU97, RLMN_AGRVS;  B2UNF2, RLMN_AKKM8;  Q0VND7, RLMN_ALCBS;  
B6EGY4, RLMN_ALISL;  Q0A989, RLMN_ALKEH;  A6TRW3, RLMN_ALKMQ;  
A8MH89, RLMN_ALKOO;  Q2IIC5, RLMN_ANADE;  A7HCD6, RLMN_ANADF;  
Q3M9B9, RLMN_ANAVT;  O66732, RLMN_AQUAE;  A8EQW8, RLMN_ARCB4;  
Q5P7B0, RLMN_AROAE;  A8IQ73, RLMN_AZOC5;  A1K3Y6, RLMN_AZOSB;  
C3P635, RLMN_BACAA;  C3L763, RLMN_BACAC;  A0RHN7, RLMN_BACAH;  
Q81WH4, RLMN_BACAN;  B7JJV1, RLMN_BACC0;  Q732K6, RLMN_BACC1;  
B7IUM3, RLMN_BACC2;  C1EP88, RLMN_BACC3;  B7HDY7, RLMN_BACC4;  
B7HLJ7, RLMN_BACC7;  A7GRJ4, RLMN_BACCN;  B9IVF3, RLMN_BACCQ;  
Q819U3, RLMN_BACCR;  Q636G2, RLMN_BACCZ;  Q5LGK5, RLMN_BACFN;  
Q64XE8, RLMN_BACFR;  Q9K9Y8, RLMN_BACHD;  Q6HEV1, RLMN_BACHK;  
Q65JS3, RLMN_BACLD;  A7Z4J5, RLMN_BACMF;  A8FD40, RLMN_BACP2;  
Q5WKB6, RLMN_BACSK;  O34617, RLMN_BACSU;  Q89ZK5, RLMN_BACTN;  
A6L3I9, RLMN_BACV8;  A9VTA2, RLMN_BACWK;  A1UUF7, RLMN_BARBK;  
Q6G592, RLMN_BARHE;  Q6G1C0, RLMN_BARQU;  A9IL44, RLMN_BART1;  
Q6MPV7, RLMN_BDEBA;  B2IGZ5, RLMN_BEII9;  A1A1I4, RLMN_BIFAA;  
Q8G481, RLMN_BIFLO;  Q492D9, RLMN_BLOPB;  Q2KY87, RLMN_BORA1;  
Q7WHM8, RLMN_BORBR;  Q7W6P5, RLMN_BORPA;  A9IK57, RLMN_BORPD;  
Q7VWK8, RLMN_BORPE;  Q89X03, RLMN_BRADU;  A5E8P3, RLMN_BRASB;  
A4YJY2, RLMN_BRASO;  B2S7X6, RLMN_BRUA1;  Q2YNV3, RLMN_BRUA2;  
Q57FT9, RLMN_BRUAB;  A9M6S9, RLMN_BRUC2;  C0RGD9, RLMN_BRUMB;  
Q8YEL1, RLMN_BRUME;  A5VN22, RLMN_BRUO2;  B0CII9, RLMN_BRUSI;  
Q8G374, RLMN_BRUSU;  P57373, RLMN_BUCAI;  Q8K9P5, RLMN_BUCAP;  
Q89AK8, RLMN_BUCBP;  Q057Q1, RLMN_BUCCC;  B1YR46, RLMN_BURA4;  
Q1BGX6, RLMN_BURCA;  B1JT94, RLMN_BURCC;  A0K7T8, RLMN_BURCH;  
B4EAX1, RLMN_BURCJ;  Q0BEW5, RLMN_BURCM;  Q39FQ7, RLMN_BURL3;  
A3MK77, RLMN_BURM7;  A2S2A0, RLMN_BURM9;  Q62JW2, RLMN_BURMA;  
A1V4K3, RLMN_BURMS;  A3NVX3, RLMN_BURP0;  Q3JRQ1, RLMN_BURP1;  
A3NA56, RLMN_BURP6;  B2JIV3, RLMN_BURP8;  B2SXT2, RLMN_BURPP;  
Q63UT5, RLMN_BURPS;  Q2SWE6, RLMN_BURTA;  A4JEP2, RLMN_BURVG;  
Q13X26, RLMN_BURXL;  Q8R9T4, RLMN_CALS4;  A4XL78, RLMN_CALS8;  
A7ZGB0, RLMN_CAMC1;  A7GVW3, RLMN_CAMC5;  A0RRU0, RLMN_CAMFF;  
A7I414, RLMN_CAMHC;  A8FP27, RLMN_CAMJ8;  A7H662, RLMN_CAMJD;  
Q0P7R8, RLMN_CAMJE;  A1W1W6, RLMN_CAMJJ;  Q5HS83, RLMN_CAMJR;  
B9KEA4, RLMN_CAMLR;  Q3AC22, RLMN_CARHZ;  B8GXM4, RLMN_CAUCN;  
Q9ABT6, RLMN_CAUCR;  B0T387, RLMN_CAUSK;  Q11EE0, RLMN_CHESB;  
A9WFY6, RLMN_CHLAA;  Q3ASD4, RLMN_CHLCH;  B3ED49, RLMN_CHLL2;  
Q3B4B8, RLMN_CHLL7;  B3EJF5, RLMN_CHLPB;  A1BGN4, RLMN_CHLPD;  
A4SEQ5, RLMN_CHLPM;  B3QS43, RLMN_CHLT3;  Q8KD71, RLMN_CHLTE;  
Q1QTL1, RLMN_CHRSD;  Q7NS85, RLMN_CHRVO;  A8AD69, RLMN_CITK8;  
Q97IC4, RLMN_CLOAB;  A7FW72, RLMN_CLOB1;  A6LSK1, RLMN_CLOB8;  
B2V4B5, RLMN_CLOBA;  B2THS9, RLMN_CLOBB;  A5I4T4, RLMN_CLOBH;  
B1IIL7, RLMN_CLOBK;  A7GG92, RLMN_CLOBL;  B1KX56, RLMN_CLOBM;  
B8I259, RLMN_CLOCE;  A0Q112, RLMN_CLONN;  Q0TPL4, RLMN_CLOP1;  
Q8XJL6, RLMN_CLOPE;  A9KM95, RLMN_CLOPH;  Q0SS81, RLMN_CLOPS;  
Q895P8, RLMN_CLOTE;  A3DCX9, RLMN_CLOTH;  Q47WB7, RLMN_COLP3;  
Q6NGK9, RLMN_CORDI;  Q8FP78, RLMN_COREF;  A4QF26, RLMN_CORGB;  
Q8NP06, RLMN_CORGL;  Q4JV24, RLMN_CORJK;  B6J7Q9, RLMN_COXB1;  
B6IZM7, RLMN_COXB2;  A9KFV0, RLMN_COXBN;  A9NDW2, RLMN_COXBR;  
Q83C77, RLMN_COXBU;  A7MGV3, RLMN_CROS8;  Q1LLI8, RLMN_CUPMC;  
Q0K959, RLMN_CUPNH;  Q46ZI0, RLMN_CUPPJ;  B1WU13, RLMN_CYAA5;  
B7K4N4, RLMN_CYAP8;  Q11QF0, RLMN_CYTH3;  Q47BR3, RLMN_DECAR;  
C1CVX7, RLMN_DEIDV;  Q1J0P9, RLMN_DEIGD;  Q9RVT6, RLMN_DEIRA;  
A9BMV6, RLMN_DELAS;  Q30X35, RLMN_DESAG;  B1I501, RLMN_DESAP;  
B8FS78, RLMN_DESHD;  Q24U12, RLMN_DESHY;  C4XTP4, RLMN_DESMR;  
A8ZV25, RLMN_DESOH;  Q6ALW1, RLMN_DESPS;  A4J582, RLMN_DESRM;  
Q727F1, RLMN_DESVH;  B8DRU2, RLMN_DESVM;  A1VAL8, RLMN_DESVV;  
A5EVN1, RLMN_DICNV;  B5YF42, RLMN_DICT6;  B8E0X3, RLMN_DICTD;  
A8LNF0, RLMN_DINSH;  A7ZPW0, RLMN_ECO24;  B7UGW3, RLMN_ECO27;  
B7MI02, RLMN_ECO45;  B7LDA9, RLMN_ECO55;  Q8XAA4, RLMN_ECO57;  
B5Z0Y6, RLMN_ECO5E;  B7NRG7, RLMN_ECO7I;  B7N304, RLMN_ECO81;  
B7M7M1, RLMN_ECO8A;  C4ZX92, RLMN_ECOBW;  B1XAZ2, RLMN_ECODH;  
A8A323, RLMN_ECOHS;  A1AE55, RLMN_ECOK1;  Q0TEW8, RLMN_ECOL5;  
Q8FF55, RLMN_ECOL6;  B1IWE4, RLMN_ECOLC;  P36979, RLMN_ECOLI;  
B7N6A5, RLMN_ECOLU;  B6I589, RLMN_ECOSE;  B1LNH2, RLMN_ECOSM;  
Q1R8L6, RLMN_ECOUT;  C5BET4, RLMN_EDWI9;  A4WD95, RLMN_ENT38;  
Q833B6, RLMN_ENTFA;  B2VE98, RLMN_ERWT9;  Q2N9J2, RLMN_ERYLH;  
B7LKC1, RLMN_ESCF3;  C4Z523, RLMN_EUBE2;  B1YG36, RLMN_EXIS2;  
A7HNQ1, RLMN_FERNB;  B0S143, RLMN_FINM2;  A5FJ06, RLMN_FLAJ1;  
A6H1B8, RLMN_FLAPJ;  Q0RDQ8, RLMN_FRAAA;  B0U083, RLMN_FRAP2;  
Q2J713, RLMN_FRASC;  A8L6D8, RLMN_FRASN;  Q14HF5, RLMN_FRAT1;  
A7NC58, RLMN_FRATF;  Q2A3H3, RLMN_FRATH;  B2SGH6, RLMN_FRATM;  
A0Q6H0, RLMN_FRATN;  Q0BLY6, RLMN_FRATO;  Q5NG03, RLMN_FRATT;  
A4IY03, RLMN_FRATW;  Q8RFZ9, RLMN_FUSNN;  C1A949, RLMN_GEMAT;  
Q5L0S1, RLMN_GEOKA;  Q39S71, RLMN_GEOMG;  Q74E53, RLMN_GEOSL;  
A4IM49, RLMN_GEOTN;  A5GEC2, RLMN_GEOUR;  Q7NIV3, RLMN_GLOVI;  
Q5FUA9, RLMN_GLUOX;  Q0BV08, RLMN_GRABC;  A0LY94, RLMN_GRAFK;  
Q7VNZ4, RLMN_HAEDU;  Q4QNH7, RLMN_HAEI8;  A5UAC2, RLMN_HAEIE;  
P44665, RLMN_HAEIN;  Q0I3U8, RLMN_HAES1;  Q2SDW1, RLMN_HAHCH;  
A1WXZ3, RLMN_HALHL;  Q17ZF6, RLMN_HELAH;  Q7VGY9, RLMN_HELHP;  
B0TGT1, RLMN_HELMI;  B6JNS0, RLMN_HELP2;  B5Z947, RLMN_HELPG;  
Q1CRK2, RLMN_HELPH;  Q9ZJI4, RLMN_HELPJ;  B2UVG6, RLMN_HELPS;  
O25970, RLMN_HELPY;  A9AY55, RLMN_HERA2;  A4G4J9, RLMN_HERAR;  
B0UWR0, RLMN_HISS2;  Q0BWY9, RLMN_HYPNA;  Q5QYC0, RLMN_IDILO;  
A6SZX3, RLMN_JANMA;  Q28VS6, RLMN_JANSC;  A6W7W9, RLMN_KINRD;  
B5XNL2, RLMN_KLEP3;  A6TCD6, RLMN_KLEP7;  B2GJ15, RLMN_KOCRD;  
Q1IRD1, RLMN_KORVE;  Q9CJ27, RLMN_LACLA;  A2RHR3, RLMN_LACLM;  
Q032R6, RLMN_LACLS;  C1DD41, RLMN_LARHH;  Q1MQJ3, RLMN_LAWIP;  
Q5X516, RLMN_LEGPA;  A5IC42, RLMN_LEGPC;  Q5ZV93, RLMN_LEGPH;  
Q5WWH4, RLMN_LEGPL;  B0SGA8, RLMN_LEPBA;  Q04UG1, RLMN_LEPBJ;  
Q04Z14, RLMN_LEPBL;  B0SPQ8, RLMN_LEPBP;  B1XXL6, RLMN_LEPCP;  
Q72NP7, RLMN_LEPIC;  Q8F7V1, RLMN_LEPIN;  Q92EH6, RLMN_LISIN;  
C1KZZ3, RLMN_LISMC;  Q723G9, RLMN_LISMF;  B8DCJ5, RLMN_LISMH;  
Q8Y9P2, RLMN_LISMO;  A0AFT6, RLMN_LISW6;  B1HQE6, RLMN_LYSSC;  
A0LBZ1, RLMN_MAGMM;  Q2W897, RLMN_MAGSA;  Q65R87, RLMN_MANSM;  
A1TZP7, RLMN_MARHV;  Q0ATR3, RLMN_MARMM;  A6VV03, RLMN_MARMS;  
Q603C0, RLMN_METCA;  A9W383, RLMN_METEP;  Q1H0U6, RLMN_METFK;  
B1ZG98, RLMN_METPB;  A2SHB8, RLMN_METPP;  B1M1U6, RLMN_METRJ;  
B0UQR1, RLMN_METS4;  B8EIR0, RLMN_METSB;  B0JT33, RLMN_MICAN;  
Q2RK16, RLMN_MOOTA;  P0A645, RLMN_MYCBO;  A1KMM4, RLMN_MYCBP;  
C1AFZ5, RLMN_MYCBT;  A4TC75, RLMN_MYCGI;  B2HJP3, RLMN_MYCMM;  
Q73VR8, RLMN_MYCPA;  Q8EVK0, RLMN_MYCPE;  A0QVE4, RLMN_MYCS2;  
A3PXZ7, RLMN_MYCSJ;  A1UEJ3, RLMN_MYCSK;  Q1BAG9, RLMN_MYCSS;  
A5U6N5, RLMN_MYCTA;  P9WH14, RLMN_MYCTO;  P9WH15, RLMN_MYCTU;  
A0PQ89, RLMN_MYCUA;  A1T787, RLMN_MYCVP;  B2A2K6, RLMN_NATTJ;  
B9L721, RLMN_NAUPA;  Q5F911, RLMN_NEIG1;  B4RMG2, RLMN_NEIG2;  
A9LZN6, RLMN_NEIM0;  A1ISB3, RLMN_NEIMA;  Q9JZ42, RLMN_NEIMB;  
A1KUD6, RLMN_NEIMF;  Q0AE39, RLMN_NITEC;  Q82XV4, RLMN_NITEU;  
Q1QHE3, RLMN_NITHX;  Q2Y6F3, RLMN_NITMU;  Q3JCN4, RLMN_NITOC;  
A6Q115, RLMN_NITSB;  Q3SNT2, RLMN_NITWN;  Q5YS67, RLMN_NOCFA;  
A1SLQ4, RLMN_NOCSJ;  B2J6D0, RLMN_NOSP7;  Q8YZV0, RLMN_NOSS1;  
Q2G8E3, RLMN_NOVAD;  Q8ELW7, RLMN_OCEIH;  A6WV17, RLMN_OCHA4;  
A6L8G0, RLMN_PARD8;  A1B4Z8, RLMN_PARDP;  A7HSW7, RLMN_PARL1;  
Q9CJJ8, RLMN_PASMU;  Q6D273, RLMN_PECAS;  Q3A2Z4, RLMN_PELCD;  
B4SA62, RLMN_PELPB;  A1AL40, RLMN_PELPD;  A5D1B6, RLMN_PELTS;  
Q182S0, RLMN_PEPD6;  A9BIC0, RLMN_PETMO;  B4RCA4, RLMN_PHEZH;  
Q7N709, RLMN_PHOLL;  Q6LU52, RLMN_PHOPR;  A1VNF1, RLMN_POLNA;  
Q12AB5, RLMN_POLSJ;  A4SYE2, RLMN_POLSQ;  B2RMI0, RLMN_PORG3;  
Q7MTB0, RLMN_PORGI;  B4S808, RLMN_PROA2;  Q6A7K4, RLMN_PROAC;  
A3PEX0, RLMN_PROM0;  A2C4M8, RLMN_PROM1;  A8G6Y2, RLMN_PROM2;  
A2C6T3, RLMN_PROM3;  A9BCH2, RLMN_PROM4;  A2BYK7, RLMN_PROM5;  
Q318R1, RLMN_PROM9;  Q7VA32, RLMN_PROMA;  B4EZT6, RLMN_PROMH;  
Q7V5P5, RLMN_PROMM;  Q7V010, RLMN_PROMP;  A2BT57, RLMN_PROMS;  
Q46J26, RLMN_PROMT;  Q48LZ7, RLMN_PSE14;  Q15R53, RLMN_PSEA6;  
A6V0V7, RLMN_PSEA7;  Q02RW0, RLMN_PSEAB;  Q51385, RLMN_PSEAE;  
Q1IEI4, RLMN_PSEE4;  Q4K6U6, RLMN_PSEF5;  C3K1L7, RLMN_PSEFS;  
Q3ID16, RLMN_PSEHT;  A8F8C2, RLMN_PSELT;  A4XY35, RLMN_PSEMY;  
A5VYT2, RLMN_PSEP1;  Q3K7B3, RLMN_PSEPF;  B0KPI4, RLMN_PSEPG;  
Q88PK0, RLMN_PSEPK;  B1JDQ5, RLMN_PSEPW;  Q886Z3, RLMN_PSESM;  
Q4ZX26, RLMN_PSEU2;  A4VNX4, RLMN_PSEU5;  Q4FTX0, RLMN_PSYA2;  
Q1QD22, RLMN_PSYCK;  A1SU36, RLMN_PSYIN;  A5WGQ4, RLMN_PSYWF;  
B2U9U6, RLMN_RALPJ;  Q8Y032, RLMN_RALSO;  B3PQY8, RLMN_RHIE6;  
Q2K3B1, RLMN_RHIEC;  Q1MAN2, RLMN_RHIL3;  Q98E86, RLMN_RHILO;  
B5ZTF1, RLMN_RHILW;  Q92L68, RLMN_RHIME;  C3MAJ1, RLMN_RHISN;  
Q7UHU7, RLMN_RHOBA;  C0ZY23, RLMN_RHOE4;  Q21W25, RLMN_RHOFT;  
Q0S277, RLMN_RHOJR;  C1B2V0, RLMN_RHOOB;  Q2J405, RLMN_RHOP2;  
Q07VN5, RLMN_RHOP5;  Q6NCS3, RLMN_RHOPA;  Q21DC2, RLMN_RHOPB;  
Q13D92, RLMN_RHOPS;  B3Q9D7, RLMN_RHOPT;  Q2RP22, RLMN_RHORT;  
A3PFQ4, RLMN_RHOS1;  Q3IY22, RLMN_RHOS4;  A4WNI9, RLMN_RHOS5;  
B9KQP1, RLMN_RHOSK;  A7NPY6, RLMN_ROSCS;  Q16DM2, RLMN_ROSDO;  
A5UT23, RLMN_ROSS1;  Q1AYW0, RLMN_RUBXD;  Q5LN66, RLMN_RUEPO;  
Q1GC70, RLMN_RUEST;  A1AW44, RLMN_RUTMC;  Q21KT6, RLMN_SACD2;  
A4FMC5, RLMN_SACEN;  B5F1A0, RLMN_SALA4;  A8M6B6, RLMN_SALAI;  
A9MHL3, RLMN_SALAR;  Q57LI4, RLMN_SALCH;  B5FR66, RLMN_SALDC;  
B5R584, RLMN_SALEP;  B5RCZ4, RLMN_SALG2;  B4TD95, RLMN_SALHS;  
B4T0Q1, RLMN_SALNS;  Q5PNI4, RLMN_SALPA;  A9N1Z8, RLMN_SALPB;  
C0PYM8, RLMN_SALPC;  B5BAY3, RLMN_SALPK;  Q2S0P9, RLMN_SALRD;  
B4TR97, RLMN_SALSV;  Q8Z4P2, RLMN_SALTI;  A4X4J7, RLMN_SALTO;  
Q8ZN52, RLMN_SALTY;  A8GHW8, RLMN_SERP5;  A1S866, RLMN_SHEAM;  
B8E9S4, RLMN_SHEB2;  A3D6W2, RLMN_SHEB5;  A6WQQ0, RLMN_SHEB8;  
A9KXL1, RLMN_SHEB9;  Q12PT7, RLMN_SHEDO;  Q085U9, RLMN_SHEFN;  
B0TLI1, RLMN_SHEHH;  A3QCF9, RLMN_SHELP;  Q8EC29, RLMN_SHEON;  
A8H242, RLMN_SHEPA;  A4Y8U3, RLMN_SHEPC;  A0KUJ2, RLMN_SHESA;  
A8FT67, RLMN_SHESH;  Q0HKW2, RLMN_SHESM;  Q0HX60, RLMN_SHESR;  
A1RHQ0, RLMN_SHESW;  B1KKI9, RLMN_SHEWM;  B2TXU2, RLMN_SHIB3;  
Q31XX3, RLMN_SHIBS;  Q32D45, RLMN_SHIDS;  Q0T202, RLMN_SHIF8;  
Q83K42, RLMN_SHIFL;  Q3YZ35, RLMN_SHISS;  A6UE14, RLMN_SINMW;  
Q2NS37, RLMN_SODGM;  Q01QF9, RLMN_SOLUE;  A9FFJ6, RLMN_SORC5;  
Q1GV98, RLMN_SPHAL;  A5VAJ8, RLMN_SPHWW;  Q6XK03, RLMN_SPICI;  
A7X1H8, RLMN_STAA1;  A6U137, RLMN_STAA2;  Q2FHM0, RLMN_STAA3;  
Q2FZ66, RLMN_STAA8;  A5ISA3, RLMN_STAA9;  Q2YXJ8, RLMN_STAAB;  
Q5HGL4, RLMN_STAAC;  A6QGB8, RLMN_STAAE;  Q99UQ0, RLMN_STAAM;  
Q7A600, RLMN_STAAN;  Q6GHL7, RLMN_STAAR;  Q6G9Z5, RLMN_STAAS;  
A8Z3Q4, RLMN_STAAT;  Q8NX16, RLMN_STAAW;  B9DPM7, RLMN_STACT;  
Q5HPX3, RLMN_STAEQ;  Q8CSW0, RLMN_STAES;  Q4L5R9, RLMN_STAHJ;  
Q49WZ9, RLMN_STAS1;  Q3K2R2, RLMN_STRA1;  Q8E6Q7, RLMN_STRA3;  
Q8E1A3, RLMN_STRA5;  Q82JY3, RLMN_STRAW;  O86754, RLMN_STRCO;  
C0MBZ4, RLMN_STRE4;  B4U1T1, RLMN_STREM;  A8AVZ7, RLMN_STRGC;  
B1VYT2, RLMN_STRGG;  B4SSW3, RLMN_STRM5;  B2FNQ6, RLMN_STRMK;  
Q8DVG8, RLMN_STRMU;  Q99YU5, RLMN_STRP1;  Q04LD5, RLMN_STRP2;  
P0DF10, RLMN_STRP3;  B5E369, RLMN_STRP4;  Q5XAZ6, RLMN_STRP6;  
C1C6B0, RLMN_STRP7;  Q8P058, RLMN_STRP8;  Q1JAS5, RLMN_STRPB;  
Q1JKX6, RLMN_STRPC;  Q1JG02, RLMN_STRPD;  Q1J5R7, RLMN_STRPF;  
A2RDK1, RLMN_STRPG;  B1IAU3, RLMN_STRPI;  Q48SK0, RLMN_STRPM;  
Q97RN5, RLMN_STRPN;  P0DF11, RLMN_STRPQ;  B2INF0, RLMN_STRPS;  
B5XMB1, RLMN_STRPZ;  Q8DQG7, RLMN_STRR6;  A4W3A5, RLMN_STRS2;  
C0MD67, RLMN_STRS7;  A3CLL3, RLMN_STRSV;  Q5LY98, RLMN_STRT1;  
Q5M2V3, RLMN_STRT2;  Q03J17, RLMN_STRTD;  B9DUW7, RLMN_STRU0;  
C1CJL5, RLMN_STRZP;  Q30NR4, RLMN_SULDN;  A6QCU6, RLMN_SULNB;  
Q67PQ7, RLMN_SYMTH;  Q2LUM5, RLMN_SYNAS;  Q31MD1, RLMN_SYNE7;  
A0LQM1, RLMN_SYNFM;  Q2JRQ8, RLMN_SYNJA;  Q2JMN2, RLMN_SYNJB;  
B1XQH8, RLMN_SYNP2;  Q5MZJ6, RLMN_SYNP6;  A5GNG9, RLMN_SYNPW;  
Q7U8K0, RLMN_SYNPX;  A5GVE8, RLMN_SYNR3;  Q0I7M1, RLMN_SYNS3;  
Q3AZA0, RLMN_SYNS9;  Q3AHX9, RLMN_SYNSC;  Q0AXL8, RLMN_SYNWW;  
Q55880, RLMN_SYNY3;  Q8DG98, RLMN_THEEB;  Q47S46, RLMN_THEFY;  
A6LN47, RLMN_THEM4;  Q9X240, RLMN_THEMA;  B9K7Z6, RLMN_THENN;  
A5ILF6, RLMN_THEP1;  B0KA06, RLMN_THEP3;  B0K1Y9, RLMN_THEPX;  
B1LAW7, RLMN_THESQ;  Q72HC1, RLMN_THET2;  Q5SGZ3, RLMN_THET8;  
Q31I07, RLMN_THICR;  Q3SL73, RLMN_THIDA;  C4LC34, RLMN_TOLAT;  
Q73KZ3, RLMN_TREDE;  O83107, RLMN_TREPA;  B2S216, RLMN_TREPS;  
Q110I1, RLMN_TRIEI;  B1H070, RLMN_UNCTG;  A1WE19, RLMN_VEREI;  
A5CX33, RLMN_VESOH;  A5F3F8, RLMN_VIBC3;  A7MU39, RLMN_VIBCB;  
Q9KTX3, RLMN_VIBCH;  C3LT10, RLMN_VIBCM;  Q5E775, RLMN_VIBF1;  
B5FAW9, RLMN_VIBFM;  Q87S19, RLMN_VIBPA;  B7VJT5, RLMN_VIBTL;  
Q8DEZ6, RLMN_VIBVU;  Q7MNF3, RLMN_VIBVY;  Q8D1Y5, RLMN_WIGBR;  
Q7MSW1, RLMN_WOLSU;  Q8PKZ1, RLMN_XANAC;  Q3BTW5, RLMN_XANC5;  
Q4UUL5, RLMN_XANC8;  B0RT51, RLMN_XANCB;  Q8P984, RLMN_XANCP;  
Q2P2T0, RLMN_XANOM;  B2SMB3, RLMN_XANOP;  Q5GZT3, RLMN_XANOR;  
A7ICB3, RLMN_XANP2;  B2I7V5, RLMN_XYLF2;  Q9PG43, RLMN_XYLFA;  
B0U494, RLMN_XYLFM;  Q87B36, RLMN_XYLFT;  A1JKR9, RLMN_YERE8;  
A7FFY6, RLMN_YERP3;  Q1C5I5, RLMN_YERPA;  B2K9Q3, RLMN_YERPB;  
Q7CJM9, RLMN_YERPE;  A9R805, RLMN_YERPG;  Q1CK94, RLMN_YERPN;  
A4TMU0, RLMN_YERPP;  Q667Z6, RLMN_YERPS;  B1JS02, RLMN_YERPY;  
Q5NNQ4, RLMN_ZYMMO;  

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