To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https

ENZYME entry: EC 3.2.2.6

Accepted Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase.
Alternative Name(s)
NAD hydrolase.
NAD(+) nucleosidase.
NADase.
Nicotinamide adenine dinucleotide nucleosidase.
Reaction catalysed
NAD(+) + H(2)O <=> ADP-D-ribose + nicotinamide
Comment(s)
  • This multiunctional enzyme catalyzes both the synthesis and hydrolysis of cyclic ADP-ribose, a calcium messenger that can mobilize intracellular Ca(2+) stores and activate Ca(2+) influx to regulate a wide range of physiological processes.
  • In addition, the enzyme also catalyzes EC 2.4.99.20.
  • Cf. EC 3.2.2.5.
Cross-references
BRENDA3.2.2.6
EC2PDB3.2.2.6
ExplorEnz3.2.2.6
PRIAM enzyme-specific profiles3.2.2.6
KEGG Ligand Database for Enzyme Nomenclature3.2.2.6
IUBMB Enzyme Nomenclature3.2.2.6
IntEnz3.2.2.6
MEDLINEFind literature relating to 3.2.2.6
MetaCyc3.2.2.6
UniProtKB/Swiss-Prot
Q10588, BST1_HUMAN;  Q64277, BST1_MOUSE;  Q63072, BST1_RAT;  
P28907, CD38_HUMAN;  Q5VAN0, CD38_MACFA;  P56528, CD38_MOUSE;  
Q9MZ03, CD38_RABIT;  Q64244, CD38_RAT;  P29241, NADA_APLCA;  
Q27312, NADA_APLKU;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-