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|ADP-dependent NAD(P)H-hydrate dehydratase.
hydro-lyase (ADP-hydrolyzing; NADH-forming).|
- ADP + (6S)-6-beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine-dinucleotide <=> AMP + phosphate + NADH
- ADP + (6S)-6-beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine-dinucleotide phosphate <=> AMP + phosphate + NADPH
- Acts equally well on hydrated NADH and hydrated NADPH.
- NAD(P)H spontaneously hydrates to both the (6S)- and (6R)- isomers.
- The enzyme from bacteria consists of two domains, one of which acts
as an NAD(P)H-hydrate epimerase that interconverts the two isomers to
a 60:40 ratio (cf. EC 188.8.131.52), while the other catalyzes the
- Hence the enzyme can restore the complete mixture of isomers into
- The enzyme has no activity with ATP, contrary to the enzyme from
eukaryotes (cf. EC 184.108.40.206).
|PRIAM enzyme-specific profiles||220.127.116.11|
|KEGG Ligand Database for Enzyme Nomenclature||18.104.22.168|
|IUBMB Enzyme Nomenclature||22.214.171.124|
|MEDLINE||Find literature relating to 126.96.36.199|
|P94368, NNRD_BACSU; ||Q7VU32, NNRD_BORPE; ||A0RU82, NNRD_CENSY; |
|Q833Y3, NNRD_ENTFA; ||A6GXW4, NNRD_FLAPJ; ||D2RXF6, NNRD_HALTV; |
|Q9CIU7, NNRD_LACLA; ||F9UN92, NNRD_LACPL; ||Q8Y6R2, NNRD_LISMO; |
|D3SQW0, NNRD_NATMM; ||Q5F8G9, NNRD_NEIG1; ||Q9JRZ9, NNRD_NEIMB; |
|A9A498, NNRD_NITMS; ||Q7UFW7, NNRD_RHOBA; ||Q2G2P8, NNRD_STAA8; |
|Q8DQD2, NNRD_STRR6; ||P96051, NNRD_STRTR; ||Q8PBP3, NNRD_XANCP; |
|O67377, NNR_AQUAE; ||O29407, NNR_ARCFU; ||Q8NSS3, NNR_CORGL; |
|Q83CM5, NNR_COXBU; ||B8E2P6, NNR_DICTD; ||P31806, NNR_ECOLI; |
|Q7NIE6, NNR_GLOVI; ||Q9ZJM4, NNR_HELPJ; ||P56176, NNR_HELPY; |
|A2BLC0, NNR_HYPBU; ||B1L3W1, NNR_KORCO; ||A4H7T9, NNR_LEIBR; |
|A4HW65, NNR_LEIIN; ||Q4QFL5, NNR_LEIMA; ||Q2FT57, NNR_METHJ; |
|Q58981, NNR_METJA; ||Q8TX67, NNR_METKA; ||O27324, NNR_METTH; |
|Q2RGI2, NNR_MOOTA; ||P37391, NNR_MYCLE; ||P9WF10, NNR_MYCTO; |
|P9WF11, NNR_MYCTU; ||Q8ZV04, NNR_PYRAE; ||Q2S580, NNR_SALRD; |
|P74217, NNR_SYNY3; ||D1BAA5, NNR_THEAS; ||Q8DGC3, NNR_THEEB; |
|Q9X024, NNR_THEMA; ||A1S0R2, NNR_THEPD; ||B5YIM0, NNR_THEYD; |
|Q9KMX5, NNR_VIBCH; |
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