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ENZYME entry: EC 22.214.171.124
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|Dopamine + 4-hydroxyphenylacetaldehyde <=> (S)-norcoclaurine + H(2)O|
- The reaction makes a 6-membered ring by forming a bond between C-6 of
the 3,4-dihydroxyphenyl group of the dopamine and C-1 of the aldehyde
in the imine formed between the substrates.
- The product is the precursor of the benzylisoquinoline alkaloids in
- Will also catalyze the reaction of 4-(2-aminoethyl)benzene-1,2-diol +
(3,4-dihydroxyphenyl)acetaldehyde to form (S)-norlaudanosoline,
but this alkaloid has not been found to occur in plants.
|PRIAM enzyme-specific profiles||126.96.36.199|
|KEGG Ligand Database for Enzyme Nomenclature||188.8.131.52|
|IUBMB Enzyme Nomenclature||184.108.40.206|
|MEDLINE||Find literature relating to 220.127.116.11|
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entries corresponding to 4.2.1.-
entries corresponding to 4.2.-.-
entries corresponding to 4.-.-.-