ENZYME entry: EC 5.3.1.24

Accepted Name
Phosphoribosylanthranilate isomerase.
Alternative Name(s)
N-(5'-phosphoribosyl)anthranilate isomerase.
PRAI.
Reaction catalysed
N-(5-phospho-beta-D-ribosyl)anthranilate <=> 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
Comment(s)
In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 2.4.2.18, EC 4.1.1.48, EC 4.1.3.27, and EC 4.2.1.20).
Cross-references
BRENDA5.3.1.24
EC2PDB5.3.1.24
ExplorEnz5.3.1.24
PRIAM enzyme-specific profiles5.3.1.24
KEGG Ligand Database for Enzyme Nomenclature5.3.1.24
IUBMB Enzyme Nomenclature5.3.1.24
IntEnz5.3.1.24
MEDLINEFind literature relating to 5.3.1.24
MetaCyc5.3.1.24
UniProtKB/Swiss-Prot
A0QHH8, HIS4_MYCA1;  B1MBX5, HIS4_MYCA9;  P60579, HIS4_MYCBO;  
A1KJ19, HIS4_MYCBP;  C1ANM5, HIS4_MYCBT;  Q9CC56, HIS4_MYCLE;  
P60583, HIS4_MYCPA;  A3Q127, HIS4_MYCSJ;  A1UHK4, HIS4_MYCSK;  
Q1B7G8, HIS4_MYCSS;  A5U2V9, HIS4_MYCTA;  P9WMM4, HIS4_MYCTO;  
P9WMM5, HIS4_MYCTU;  A0PP18, HIS4_MYCUA;  A1T8W5, HIS4_MYCVP;  
Q82AA1, HIS4_STRAW;  P16250, HIS4_STRCO;  B1W0M4, HIS4_STRGG;  
Q42440, PAI1_ARATH;  Q42527, PAI2_ARATH;  Q8LPI9, PAI3_ARATH;  
P57366, TRPC_BUCAI;  P42393, TRPC_BUCAP;  P59459, TRPC_BUCBP;  
O68427, TRPC_BUCDN;  Q44603, TRPC_BUCSC;  P06560, TRPC_CORGL;  
Q8X7B7, TRPC_ECO57;  P00909, TRPC_ECOLI;  P46451, TRPC_HAEIN;  
Q9ZJU8, TRPC_HELPJ;  O25867, TRPC_HELPY;  P57855, TRPC_PASMU;  
P24920, TRPC_PHYPR;  Q8Z7D9, TRPC_SALTI;  P00910, TRPC_SALTY;  
Q9KST5, TRPC_VIBCH;  P22098, TRPC_VIBPA;  Q8ZEG8, TRPC_YERPE;  
Q8PT98, TRPF1_METMA;  Q8PRX4, TRPF2_METMA;  B0CA72, TRPF_ACAM1;  
P16923, TRPF_ACICA;  A5FZ94, TRPF_ACICJ;  B7J4T0, TRPF_ACIF2;  
Q9Y8T6, TRPF_AERPE;  B9JG42, TRPF_AGRRK;  Q8UJB1, TRPF_AGRT5;  
B9JXV5, TRPF_AGRVS;  Q0VPI8, TRPF_ALCBS;  Q3MA33, TRPF_ANAVT;  
O67853, TRPF_AQUAE;  O28671, TRPF_ARCFU;  Q757J9, TRPF_ASHGO;  
A8HQ40, TRPF_AZOC5;  C1DQD4, TRPF_AZOVD;  A7Z617, TRPF_BACA2;  
C3P3T9, TRPF_BACAA;  C3LAV9, TRPF_BACAC;  A0RB63, TRPF_BACAH;  
Q81TL9, TRPF_BACAN;  B7JES9, TRPF_BACC0;  Q73BQ8, TRPF_BACC1;  
B7IM75, TRPF_BACC2;  C1ELE9, TRPF_BACC3;  B7HH00, TRPF_BACC4;  
B7I0F1, TRPF_BACC7;  B9IU37, TRPF_BACCQ;  Q81GG6, TRPF_BACCR;  
Q63EC8, TRPF_BACCZ;  Q9KCB1, TRPF_BACHD;  Q6HLU5, TRPF_BACHK;  
Q65I34, TRPF_BACLD;  P70938, TRPF_BACMQ;  Q5WGS2, TRPF_BACSK;  
P20167, TRPF_BACSU;  A6L7N0, TRPF_BACV8;  A9VJW1, TRPF_BACWK;  
B2IKV4, TRPF_BEII9;  Q2KYM1, TRPF_BORA1;  Q7WKG8, TRPF_BORBR;  
Q7W923, TRPF_BORPA;  A9IRJ9, TRPF_BORPD;  Q7VY68, TRPF_BORPE;  
Q89WE6, TRPF_BRADU;  A5E8A5, TRPF_BRASB;  A4YJI7, TRPF_BRASO;  
C0ZCE4, TRPF_BREBN;  B2S9A6, TRPF_BRUA1;  Q2YQW4, TRPF_BRUA2;  
Q57AE9, TRPF_BRUAB;  A9M9U3, TRPF_BRUC2;  C0RFZ5, TRPF_BRUMB;  
P67003, TRPF_BRUME;  B0CJK9, TRPF_BRUSI;  P67004, TRPF_BRUSU;  
A8FKD6, TRPF_CAMJ8;  Q9PIF3, TRPF_CAMJE;  Q5HWC0, TRPF_CAMJR;  
P43073, TRPF_CANAL;  P50857, TRPF_CANGA;  P12289, TRPF_CAUCR;  
B0T692, TRPF_CAUSK;  B3PFN8, TRPF_CELJU;  Q3AQC1, TRPF_CHLCH;  
Q822W4, TRPF_CHLCV;  Q254S9, TRPF_CHLFF;  Q9PK67, TRPF_CHLMU;  
B3QMF2, TRPF_CHLP8;  B3EKM6, TRPF_CHLPB;  A1BEZ1, TRPF_CHLPD;  
B0B7P4, TRPF_CHLT2;  B3QS44, TRPF_CHLT3;  Q3KM33, TRPF_CHLTA;  
B0BBV9, TRPF_CHLTB;  Q8KEH1, TRPF_CHLTE;  O84331, TRPF_CHLTR;  
Q1QY43, TRPF_CHRSD;  Q97EF4, TRPF_CLOAB;  A6LU95, TRPF_CLOB8;  
B9E150, TRPF_CLOK1;  A5N7N9, TRPF_CLOK5;  A9KL42, TRPF_CLOPH;  
A3DDS6, TRPF_CLOTH;  B1WT19, TRPF_CYAA5;  B7KC08, TRPF_CYAP7;  
B7JUH3, TRPF_CYAP8;  Q47HQ6, TRPF_DECAR;  Q3Z6G4, TRPF_DEHE1;  
Q3ZZ13, TRPF_DEHSC;  Q9RY28, TRPF_DEIRA;  B8FA39, TRPF_DESAA;  
C6C1D3, TRPF_DESAD;  B1I3Z6, TRPF_DESAP;  B8J162, TRPF_DESDA;  
B8FVH4, TRPF_DESHD;  Q24SK5, TRPF_DESHY;  A4J148, TRPF_DESRM;  
Q2N9N2, TRPF_ERYLH;  B5EBV0, TRPF_GEOBB;  B9M5M0, TRPF_GEODF;  
B3E754, TRPF_GEOLS;  Q39SQ9, TRPF_GEOMG;  Q74AH7, TRPF_GEOSL;  
C6DYM2, TRPF_GEOSM;  A4IQ83, TRPF_GEOTN;  A5GES5, TRPF_GEOUR;  
Q7NML1, TRPF_GLOVI;  Q0BQI7, TRPF_GRABC;  Q2SJD2, TRPF_HAHCH;  
A1WY07, TRPF_HALHL;  B9LQ97, TRPF_HALLT;  Q5V212, TRPF_HALMA;  
B0R621, TRPF_HALS3;  Q9HPG4, TRPF_HALSA;  P52563, TRPF_HALVD;  
Q875I3, TRPF_HANAN;  A4G4G1, TRPF_HERAR;  Q0BWJ4, TRPF_HYPNA;  
Q28LA8, TRPF_JANSC;  P13997, TRPF_KLULA;  Q03CY2, TRPF_LACC3;  
P17218, TRPF_LACCA;  B3W6W7, TRPF_LACCB;  Q02002, TRPF_LACLA;  
Q88WI1, TRPF_LACPL;  Q5X5Q3, TRPF_LEGPA;  A5IBF6, TRPF_LEGPC;  
Q5ZVY5, TRPF_LEGPH;  Q5WX33, TRPF_LEGPL;  Q04RT3, TRPF_LEPBJ;  
Q051T8, TRPF_LEPBL;  B1XY47, TRPF_LEPCP;  Q72RH2, TRPF_LEPIC;  
Q8F495, TRPF_LEPIN;  Q01128, TRPF_LIPST;  Q92B80, TRPF_LISIN;  
C1KVS6, TRPF_LISMC;  Q71Z39, TRPF_LISMF;  B8DHB3, TRPF_LISMH;  
Q8Y6Q5, TRPF_LISMO;  A0AJ81, TRPF_LISW6;  Q2W020, TRPF_MAGSA;  
A0LA38, TRPF_MAGSM;  A1U0X4, TRPF_MARAV;  Q0ATJ7, TRPF_MARMM;  
A6VWY4, TRPF_MARMS;  Q11KK8, TRPF_MESSB;  A6UW24, TRPF_META3;  
Q8TLP6, TRPF_METAC;  A7I4T5, TRPF_METB6;  Q57893, TRPF_METJA;  
Q8TXZ9, TRPF_METKA;  A4FXH5, TRPF_METM5;  A9AAU4, TRPF_METM6;  
A6VFU0, TRPF_METM7;  Q6LYI7, TRPF_METMP;  A2SHS5, TRPF_METPP;  
O27695, TRPF_METTH;  P26941, TRPF_METTM;  A0B9D8, TRPF_METTP;  
P14718, TRPF_METVO;  A6UP16, TRPF_METVS;  B0JNJ4, TRPF_MICAN;  
Q2RIT8, TRPF_MOOTA;  Q1CZH4, TRPF_MYXXD;  Q3IQ37, TRPF_NATPD;  
Q5F9X5, TRPF_NEIG1;  B4RJU3, TRPF_NEIG2;  A9M342, TRPF_NEIM0;  
Q9JVD1, TRPF_NEIMA;  Q9K0C6, TRPF_NEIMB;  A1KSV1, TRPF_NEIMF;  
Q0AGX6, TRPF_NITEC;  Q82WI3, TRPF_NITEU;  Q1QS32, TRPF_NITHX;  
Q2Y7R3, TRPF_NITMU;  Q3JCB9, TRPF_NITOC;  A6Q1S6, TRPF_NITSB;  
Q3SWL7, TRPF_NITWN;  B2J1L6, TRPF_NOSP7;  Q8YLL0, TRPF_NOSS1;  
Q8ESU3, TRPF_OCEIH;  B6JCP1, TRPF_OLICO;  A6L9J9, TRPF_PARD8;  
A1B8L1, TRPF_PARDP;  A7HPD4, TRPF_PARL1;  Q3B533, TRPF_PELLD;  
B4SD44, TRPF_PELPB;  A1ANJ2, TRPF_PELPD;  A9BHQ4, TRPF_PETMO;  
O13504, TRPF_PICPA;  B4S715, TRPF_PROA2;  A4SF78, TRPF_PROVI;  
Q48L25, TRPF_PSE14;  A6V2W1, TRPF_PSEA7;  B7VBQ7, TRPF_PSEA8;  
Q02PS6, TRPF_PSEAB;  Q59649, TRPF_PSEAE;  Q1ICS3, TRPF_PSEE4;  
Q4KEZ9, TRPF_PSEF5;  C3JZS5, TRPF_PSEFS;  A5W6Y0, TRPF_PSEP1;  
Q3KF16, TRPF_PSEPF;  B0KF94, TRPF_PSEPG;  Q88LE0, TRPF_PSEPK;  
B1J538, TRPF_PSEPW;  Q87YI1, TRPF_PSESM;  Q4ZVW1, TRPF_PSEU2;  
A4VKF4, TRPF_PSEU5;  Q9V1G7, TRPF_PYRAB;  Q8ZV18, TRPF_PYRAE;  
A4WKQ6, TRPF_PYRAR;  Q8U092, TRPF_PYRFU;  A1RVT3, TRPF_PYRIL;  
B2U6Z0, TRPF_RALPJ;  Q8XXX9, TRPF_RALSO;  B3PVV1, TRPF_RHIE6;  
Q2KE83, TRPF_RHIEC;  Q1MND7, TRPF_RHIL3;  Q98CN8, TRPF_RHILO;  
B5ZV69, TRPF_RHILW;  Q92TD0, TRPF_RHIME;  C3MB98, TRPF_RHISN;  
B6IVY6, TRPF_RHOCS;  Q2J2G3, TRPF_RHOP2;  Q07UH2, TRPF_RHOP5;  
Q6NDN7, TRPF_RHOPA;  Q21CB8, TRPF_RHOPB;  Q13EQ3, TRPF_RHOPS;  
B3Q604, TRPF_RHOPT;  Q2RNS6, TRPF_RHORT;  A3PPV2, TRPF_RHOS1;  
Q9X4E3, TRPF_RHOS4;  A7NS83, TRPF_ROSCS;  A5UYU9, TRPF_ROSS1;  
Q1AU93, TRPF_RUBXD;  Q1GK79, TRPF_RUEST;  Q5XQP9, TRPF_SACK1;  
Q2S1Z4, TRPF_SALRD;  A6UEI0, TRPF_SINMW;  Q01NI7, TRPF_SOLUE;  
A7X235, TRPF_STAA1;  Q2FH65, TRPF_STAA3;  Q2FYR5, TRPF_STAA8;  
Q2YXU8, TRPF_STAAB;  Q5HG48, TRPF_STAAC;  P67005, TRPF_STAAM;  
P67006, TRPF_STAAN;  Q6GH34, TRPF_STAAR;  Q6G9I8, TRPF_STAAS;  
P67007, TRPF_STAAW;  B9DP52, TRPF_STACT;  Q5HPH1, TRPF_STAEQ;  
Q8CSN5, TRPF_STAES;  Q4L678, TRPF_STAHJ;  A8AW04, TRPF_STRGC;  
B4SQV5, TRPF_STRM5;  B2FNZ5, TRPF_STRMK;  Q8DVF4, TRPF_STRMU;  
Q04IY8, TRPF_STRP2;  B5E7M4, TRPF_STRP4;  C1C967, TRPF_STRP7;  
B1I7S8, TRPF_STRPI;  B8ZN60, TRPF_STRPJ;  Q97P31, TRPF_STRPN;  
Q8DNM7, TRPF_STRR6;  C1CG43, TRPF_STRZJ;  C1CMD4, TRPF_STRZP;  
C1CT52, TRPF_STRZT;  Q4J8X6, TRPF_SULAC;  A6QC86, TRPF_SULNB;  
P50386, TRPF_SULSO;  B2V7Q4, TRPF_SULSY;  Q67PJ5, TRPF_SYMTH;  
Q2LUD8, TRPF_SYNAS;  Q31R79, TRPF_SYNE7;  Q2JW90, TRPF_SYNJA;  
Q2JPT2, TRPF_SYNJB;  B1XNB2, TRPF_SYNP2;  Q5N322, TRPF_SYNP6;  
Q0B004, TRPF_SYNWW;  P74435, TRPF_SYNY3;  Q8DGP3, TRPF_THEEB;  
Q9YGB1, TRPF_THEKO;  Q56320, TRPF_THEMA;  B9K6Z3, TRPF_THENN;  
A5IKT2, TRPF_THEP1;  B0K8T5, TRPF_THEP3;  B0K2U0, TRPF_THEPX;  
B1LA13, TRPF_THESQ;  Q8R9M8, TRPF_THETN;  Q979V6, TRPF_THEVO;  
B5YKL4, TRPF_THEYD;  Q3SHL8, TRPF_THIDA;  Q10XS2, TRPF_TRIEI;  
Q0W628, TRPF_UNCMA;  B1GZC1, TRPF_UNCTG;  Q8PJ26, TRPF_XANAC;  
Q3BRL1, TRPF_XANC5;  Q4UWD4, TRPF_XANC8;  B0RR82, TRPF_XANCB;  
Q8P7R6, TRPF_XANCP;  Q2P0U0, TRPF_XANOM;  B2SVN9, TRPF_XANOP;  
Q5GXR3, TRPF_XANOR;  B2I9J1, TRPF_XYLF2;  Q9PDK5, TRPF_XYLFA;  
B0U6K5, TRPF_XYLFM;  Q87DS0, TRPF_XYLFT;  P00912, TRPF_YEAST;  
Q9HFW8, TRPF_ZYGBA;  Q5NPZ5, TRPF_ZYMMO;  Q9S3U4, TRPF_ZYMMT;  
P18483, TRPG_ASPAW;  P05328, TRPG_ASPNG;  Q92411, TRPG_COCHE;  
P0CN87, TRPG_CRYNB;  P27710, TRPG_CRYNH;  P0CN86, TRPG_CRYNJ;  
P06531, TRPG_EMENI;  P00908, TRPG_NEUCR;  P24773, TRPG_PENCH;  
P25170, TRPG_PHACH;  P20409, TRPG_PHYBL;  Q92370, TRPG_SCHPO;  

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