ENZYME entry: EC 5.3.1.24

Accepted Name
Phosphoribosylanthranilate isomerase.
Alternative Name(s)
N-(5'-phosphoribosyl)anthranilate isomerase.
PRAI.
Reaction catalysed
N-(5-phospho-beta-D-ribosyl)anthranilate <=> 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
Comment(s)
In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 2.4.2.18, EC 4.1.1.48, EC 4.1.3.27, and EC 4.2.1.20).
Cross-references
BRENDA5.3.1.24
EC2PDB5.3.1.24
ExplorEnz5.3.1.24
PRIAM enzyme-specific profiles5.3.1.24
KEGG Ligand Database for Enzyme Nomenclature5.3.1.24
IUBMB Enzyme Nomenclature5.3.1.24
IntEnz5.3.1.24
MEDLINEFind literature relating to 5.3.1.24
MetaCyc5.3.1.24
UniProtKB/Swiss-Prot
A0QHH8, HIS4_MYCA1;  B1MBX5, HIS4_MYCA9;  P60579, HIS4_MYCBO;  
A1KJ19, HIS4_MYCBP;  C1ANM5, HIS4_MYCBT;  Q9CC56, HIS4_MYCLE;  
P60583, HIS4_MYCPA;  A3Q127, HIS4_MYCSJ;  A1UHK4, HIS4_MYCSK;  
Q1B7G8, HIS4_MYCSS;  A5U2V9, HIS4_MYCTA;  P60578, HIS4_MYCTU;  
A0PP18, HIS4_MYCUA;  A1T8W5, HIS4_MYCVP;  Q82AA1, HIS4_STRAW;  
P16250, HIS4_STRCO;  B1W0M4, HIS4_STRGG;  Q42440, PAI1_ARATH;  
Q42527, PAI2_ARATH;  Q8LPI9, PAI3_ARATH;  P57366, TRPC_BUCAI;  
P42393, TRPC_BUCAP;  P59459, TRPC_BUCBP;  O68427, TRPC_BUCDN;  
Q44603, TRPC_BUCSC;  P06560, TRPC_CORGL;  Q8X7B7, TRPC_ECO57;  
P00909, TRPC_ECOLI;  P46451, TRPC_HAEIN;  Q9ZJU8, TRPC_HELPJ;  
O25867, TRPC_HELPY;  P57855, TRPC_PASMU;  P24920, TRPC_PHYPR;  
Q8Z7D9, TRPC_SALTI;  P00910, TRPC_SALTY;  Q9KST5, TRPC_VIBCH;  
P22098, TRPC_VIBPA;  Q8ZEG8, TRPC_YERPE;  Q8PT98, TRPF1_METMA;  
Q8PRX4, TRPF2_METMA;  B0CA72, TRPF_ACAM1;  P16923, TRPF_ACICA;  
A5FZ94, TRPF_ACICJ;  B7J4T0, TRPF_ACIF2;  Q9Y8T6, TRPF_AERPE;  
B9JG42, TRPF_AGRRK;  Q8UJB1, TRPF_AGRT5;  B9JXV5, TRPF_AGRVS;  
Q0VPI8, TRPF_ALCBS;  Q3MA33, TRPF_ANAVT;  O67853, TRPF_AQUAE;  
O28671, TRPF_ARCFU;  Q757J9, TRPF_ASHGO;  A8HQ40, TRPF_AZOC5;  
C1DQD4, TRPF_AZOVD;  A7Z617, TRPF_BACA2;  C3P3T9, TRPF_BACAA;  
C3LAV9, TRPF_BACAC;  A0RB63, TRPF_BACAH;  Q81TL9, TRPF_BACAN;  
B7JES9, TRPF_BACC0;  Q73BQ8, TRPF_BACC1;  B7IM75, TRPF_BACC2;  
C1ELE9, TRPF_BACC3;  B7HH00, TRPF_BACC4;  B7I0F1, TRPF_BACC7;  
B9IU37, TRPF_BACCQ;  Q81GG6, TRPF_BACCR;  Q63EC8, TRPF_BACCZ;  
Q9KCB1, TRPF_BACHD;  Q6HLU5, TRPF_BACHK;  Q65I34, TRPF_BACLD;  
P70938, TRPF_BACMQ;  Q5WGS2, TRPF_BACSK;  P20167, TRPF_BACSU;  
A6L7N0, TRPF_BACV8;  A9VJW1, TRPF_BACWK;  B2IKV4, TRPF_BEII9;  
Q2KYM1, TRPF_BORA1;  Q7WKG8, TRPF_BORBR;  Q7W923, TRPF_BORPA;  
A9IRJ9, TRPF_BORPD;  Q7VY68, TRPF_BORPE;  Q89WE6, TRPF_BRADU;  
A5E8A5, TRPF_BRASB;  A4YJI7, TRPF_BRASO;  C0ZCE4, TRPF_BREBN;  
B2S9A6, TRPF_BRUA1;  Q2YQW4, TRPF_BRUA2;  Q57AE9, TRPF_BRUAB;  
A9M9U3, TRPF_BRUC2;  C0RFZ5, TRPF_BRUMB;  P67003, TRPF_BRUME;  
B0CJK9, TRPF_BRUSI;  P67004, TRPF_BRUSU;  A8FKD6, TRPF_CAMJ8;  
Q9PIF3, TRPF_CAMJE;  Q5HWC0, TRPF_CAMJR;  P43073, TRPF_CANAL;  
P50857, TRPF_CANGA;  P12289, TRPF_CAUCR;  B0T692, TRPF_CAUSK;  
B3PFN8, TRPF_CELJU;  Q3AQC1, TRPF_CHLCH;  Q822W4, TRPF_CHLCV;  
Q254S9, TRPF_CHLFF;  Q9PK67, TRPF_CHLMU;  B3QMF2, TRPF_CHLP8;  
B3EKM6, TRPF_CHLPB;  A1BEZ1, TRPF_CHLPD;  B0B7P4, TRPF_CHLT2;  
B3QS44, TRPF_CHLT3;  Q3KM33, TRPF_CHLTA;  B0BBV9, TRPF_CHLTB;  
Q8KEH1, TRPF_CHLTE;  O84331, TRPF_CHLTR;  Q1QY43, TRPF_CHRSD;  
Q97EF4, TRPF_CLOAB;  A6LU95, TRPF_CLOB8;  B9E150, TRPF_CLOK1;  
A5N7N9, TRPF_CLOK5;  A9KL42, TRPF_CLOPH;  A3DDS6, TRPF_CLOTH;  
B1WT19, TRPF_CYAA5;  B7KC08, TRPF_CYAP7;  B7JUH3, TRPF_CYAP8;  
Q47HQ6, TRPF_DECAR;  Q3Z6G4, TRPF_DEHE1;  Q3ZZ13, TRPF_DEHSC;  
Q9RY28, TRPF_DEIRA;  B8FA39, TRPF_DESAA;  C6C1D3, TRPF_DESAD;  
B1I3Z6, TRPF_DESAP;  B8J162, TRPF_DESDA;  B8FVH4, TRPF_DESHD;  
Q24SK5, TRPF_DESHY;  A4J148, TRPF_DESRM;  Q2N9N2, TRPF_ERYLH;  
B5EBV0, TRPF_GEOBB;  B9M5M0, TRPF_GEODF;  B3E754, TRPF_GEOLS;  
Q39SQ9, TRPF_GEOMG;  Q74AH7, TRPF_GEOSL;  C6DYM2, TRPF_GEOSM;  
A4IQ83, TRPF_GEOTN;  A5GES5, TRPF_GEOUR;  Q7NML1, TRPF_GLOVI;  
Q0BQI7, TRPF_GRABC;  Q2SJD2, TRPF_HAHCH;  A1WY07, TRPF_HALHL;  
B9LQ97, TRPF_HALLT;  Q5V212, TRPF_HALMA;  B0R621, TRPF_HALS3;  
Q9HPG4, TRPF_HALSA;  P52563, TRPF_HALVD;  Q875I3, TRPF_HANAN;  
A4G4G1, TRPF_HERAR;  Q0BWJ4, TRPF_HYPNA;  Q28LA8, TRPF_JANSC;  
P13997, TRPF_KLULA;  Q03CY2, TRPF_LACC3;  P17218, TRPF_LACCA;  
B3W6W7, TRPF_LACCB;  Q02002, TRPF_LACLA;  Q88WI1, TRPF_LACPL;  
Q5X5Q3, TRPF_LEGPA;  A5IBF6, TRPF_LEGPC;  Q5ZVY5, TRPF_LEGPH;  
Q5WX33, TRPF_LEGPL;  Q04RT3, TRPF_LEPBJ;  Q051T8, TRPF_LEPBL;  
B1XY47, TRPF_LEPCP;  Q72RH2, TRPF_LEPIC;  Q8F495, TRPF_LEPIN;  
Q01128, TRPF_LIPST;  Q92B80, TRPF_LISIN;  C1KVS6, TRPF_LISMC;  
Q71Z39, TRPF_LISMF;  B8DHB3, TRPF_LISMH;  Q8Y6Q5, TRPF_LISMO;  
A0AJ81, TRPF_LISW6;  Q2W020, TRPF_MAGSA;  A0LA38, TRPF_MAGSM;  
A1U0X4, TRPF_MARAV;  Q0ATJ7, TRPF_MARMM;  A6VWY4, TRPF_MARMS;  
Q11KK8, TRPF_MESSB;  A6UW24, TRPF_META3;  Q8TLP6, TRPF_METAC;  
A7I4T5, TRPF_METB6;  Q57893, TRPF_METJA;  Q8TXZ9, TRPF_METKA;  
A4FXH5, TRPF_METM5;  A9AAU4, TRPF_METM6;  A6VFU0, TRPF_METM7;  
Q6LYI7, TRPF_METMP;  A2SHS5, TRPF_METPP;  O27695, TRPF_METTH;  
P26941, TRPF_METTM;  A0B9D8, TRPF_METTP;  P14718, TRPF_METVO;  
A6UP16, TRPF_METVS;  B0JNJ4, TRPF_MICAN;  Q2RIT8, TRPF_MOOTA;  
Q1CZH4, TRPF_MYXXD;  Q3IQ37, TRPF_NATPD;  Q5F9X5, TRPF_NEIG1;  
B4RJU3, TRPF_NEIG2;  A9M342, TRPF_NEIM0;  Q9JVD1, TRPF_NEIMA;  
Q9K0C6, TRPF_NEIMB;  A1KSV1, TRPF_NEIMF;  Q0AGX6, TRPF_NITEC;  
Q82WI3, TRPF_NITEU;  Q1QS32, TRPF_NITHX;  Q2Y7R3, TRPF_NITMU;  
Q3JCB9, TRPF_NITOC;  A6Q1S6, TRPF_NITSB;  Q3SWL7, TRPF_NITWN;  
B2J1L6, TRPF_NOSP7;  Q8YLL0, TRPF_NOSS1;  Q8ESU3, TRPF_OCEIH;  
B6JCP1, TRPF_OLICO;  A6L9J9, TRPF_PARD8;  A1B8L1, TRPF_PARDP;  
A7HPD4, TRPF_PARL1;  Q3B533, TRPF_PELLD;  B4SD44, TRPF_PELPB;  
A1ANJ2, TRPF_PELPD;  A9BHQ4, TRPF_PETMO;  O13504, TRPF_PICPA;  
B4S715, TRPF_PROA2;  A4SF78, TRPF_PROVI;  Q48L25, TRPF_PSE14;  
A6V2W1, TRPF_PSEA7;  B7VBQ7, TRPF_PSEA8;  Q02PS6, TRPF_PSEAB;  
Q59649, TRPF_PSEAE;  Q1ICS3, TRPF_PSEE4;  Q4KEZ9, TRPF_PSEF5;  
C3JZS5, TRPF_PSEFS;  A5W6Y0, TRPF_PSEP1;  Q3KF16, TRPF_PSEPF;  
B0KF94, TRPF_PSEPG;  Q88LE0, TRPF_PSEPK;  B1J538, TRPF_PSEPW;  
Q87YI1, TRPF_PSESM;  Q4ZVW1, TRPF_PSEU2;  A4VKF4, TRPF_PSEU5;  
Q9V1G7, TRPF_PYRAB;  Q8ZV18, TRPF_PYRAE;  A4WKQ6, TRPF_PYRAR;  
Q8U092, TRPF_PYRFU;  A1RVT3, TRPF_PYRIL;  B2U6Z0, TRPF_RALPJ;  
Q8XXX9, TRPF_RALSO;  B3PVV1, TRPF_RHIE6;  Q2KE83, TRPF_RHIEC;  
Q1MND7, TRPF_RHIL3;  Q98CN8, TRPF_RHILO;  B5ZV69, TRPF_RHILW;  
Q92TD0, TRPF_RHIME;  C3MB98, TRPF_RHISN;  B6IVY6, TRPF_RHOCS;  
Q2J2G3, TRPF_RHOP2;  Q07UH2, TRPF_RHOP5;  Q6NDN7, TRPF_RHOPA;  
Q21CB8, TRPF_RHOPB;  Q13EQ3, TRPF_RHOPS;  B3Q604, TRPF_RHOPT;  
Q2RNS6, TRPF_RHORT;  A3PPV2, TRPF_RHOS1;  Q9X4E3, TRPF_RHOS4;  
A7NS83, TRPF_ROSCS;  A5UYU9, TRPF_ROSS1;  Q1AU93, TRPF_RUBXD;  
Q1GK79, TRPF_RUEST;  Q5XQP9, TRPF_SACK1;  Q2S1Z4, TRPF_SALRD;  
A6UEI0, TRPF_SINMW;  Q01NI7, TRPF_SOLUE;  A7X235, TRPF_STAA1;  
Q2FH65, TRPF_STAA3;  Q2FYR5, TRPF_STAA8;  Q2YXU8, TRPF_STAAB;  
Q5HG48, TRPF_STAAC;  P67005, TRPF_STAAM;  P67006, TRPF_STAAN;  
Q6GH34, TRPF_STAAR;  Q6G9I8, TRPF_STAAS;  P67007, TRPF_STAAW;  
B9DP52, TRPF_STACT;  Q5HPH1, TRPF_STAEQ;  Q8CSN5, TRPF_STAES;  
Q4L678, TRPF_STAHJ;  A8AW04, TRPF_STRGC;  B4SQV5, TRPF_STRM5;  
B2FNZ5, TRPF_STRMK;  Q8DVF4, TRPF_STRMU;  Q04IY8, TRPF_STRP2;  
B5E7M4, TRPF_STRP4;  C1C967, TRPF_STRP7;  B1I7S8, TRPF_STRPI;  
B8ZN60, TRPF_STRPJ;  Q97P31, TRPF_STRPN;  Q8DNM7, TRPF_STRR6;  
C1CG43, TRPF_STRZJ;  C1CMD4, TRPF_STRZP;  C1CT52, TRPF_STRZT;  
Q4J8X6, TRPF_SULAC;  A6QC86, TRPF_SULNB;  P50386, TRPF_SULSO;  
B2V7Q4, TRPF_SULSY;  Q67PJ5, TRPF_SYMTH;  Q2LUD8, TRPF_SYNAS;  
Q31R79, TRPF_SYNE7;  Q2JW90, TRPF_SYNJA;  Q2JPT2, TRPF_SYNJB;  
B1XNB2, TRPF_SYNP2;  Q5N322, TRPF_SYNP6;  Q0B004, TRPF_SYNWW;  
P74435, TRPF_SYNY3;  Q8DGP3, TRPF_THEEB;  Q9YGB1, TRPF_THEKO;  
Q56320, TRPF_THEMA;  B9K6Z3, TRPF_THENN;  A5IKT2, TRPF_THEP1;  
B0K8T5, TRPF_THEP3;  B0K2U0, TRPF_THEPX;  B1LA13, TRPF_THESQ;  
Q8R9M8, TRPF_THETN;  Q979V6, TRPF_THEVO;  B5YKL4, TRPF_THEYD;  
Q3SHL8, TRPF_THIDA;  Q10XS2, TRPF_TRIEI;  Q0W628, TRPF_UNCMA;  
B1GZC1, TRPF_UNCTG;  Q8PJ26, TRPF_XANAC;  Q3BRL1, TRPF_XANC5;  
Q4UWD4, TRPF_XANC8;  B0RR82, TRPF_XANCB;  Q8P7R6, TRPF_XANCP;  
Q2P0U0, TRPF_XANOM;  B2SVN9, TRPF_XANOP;  Q5GXR3, TRPF_XANOR;  
B2I9J1, TRPF_XYLF2;  Q9PDK5, TRPF_XYLFA;  B0U6K5, TRPF_XYLFM;  
Q87DS0, TRPF_XYLFT;  P00912, TRPF_YEAST;  Q9HFW8, TRPF_ZYGBA;  
Q5NPZ5, TRPF_ZYMMO;  Q9S3U4, TRPF_ZYMMT;  P18483, TRPG_ASPAW;  
P05328, TRPG_ASPNG;  Q92411, TRPG_COCHE;  P0CN87, TRPG_CRYNB;  
P27710, TRPG_CRYNH;  P0CN86, TRPG_CRYNJ;  P06531, TRPG_EMENI;  
P00908, TRPG_NEUCR;  P24773, TRPG_PENCH;  P25170, TRPG_PHACH;  
P20409, TRPG_PHYBL;  Q92370, TRPG_SCHPO;  

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