ENZYME entry: EC 4.1.3.27

Accepted Name
Anthranilate synthase.
Reaction catalysed
Chorismate + L-glutamine <=> anthranilate + pyruvate + L-glutamate
Comment(s)
  • In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 2.4.2.18, EC 4.1.1.48, EC 4.2.1.20, and EC 5.3.1.24).
  • The native enzyme in the complex with uses either glutamine or (less efficiently) NH(3).
  • The enzyme separated from the complex uses NH(3) only.
Cross-references
PROSITEPDOC00405
BRENDA4.1.3.27
EC2PDB4.1.3.27
ExplorEnz4.1.3.27
PRIAM enzyme-specific profiles4.1.3.27
KEGG Ligand Database for Enzyme Nomenclature4.1.3.27
IUBMB Enzyme Nomenclature4.1.3.27
IntEnz4.1.3.27
MEDLINEFind literature relating to 4.1.3.27
MetaCyc4.1.3.27
UniProtKB/Swiss-Prot
A2XNK3, ASA1_ORYSI;  Q94GF1, ASA1_ORYSJ;  Q9XJ29, ASA2_ORYSJ;  
Q42565, ASB1_ARATH;  Q7XUS2, ASB1_ORYSJ;  Q9FJM5, ASB2_ARATH;  
Q764B9, ASB2_ORYSJ;  P28819, PABA_BACSU;  P09785, PHNA_PSEAE;  
P09786, PHNB_PSEAE;  Q51519, PHZB_PSECL;  Q51791, PHZE_PSEFL;  
P74130, TRE2_SYNY3;  Q5V448, TRPE1_HALMA;  Q9HPG5, TRPE1_HALSA;  
Q5V213, TRPE2_HALMA;  Q9HS66, TRPE2_HALSA;  Q5V631, TRPE3_HALMA;  
P23315, TRPE_ACICA;  Q9Y8T0, TRPE_AERPE;  O66849, TRPE_AQUAE;  
P32068, TRPE_ARATH;  O28669, TRPE_ARCFU;  P96556, TRPE_ARTGO;  
P50872, TRPE_AZOBR;  P30526, TRPE_BACCA;  P18267, TRPE_BACPU;  
P03963, TRPE_BACSU;  Q44695, TRPE_BUCAI;  P42387, TRPE_BUCAP;  
Q89A29, TRPE_BUCBP;  Q44697, TRPE_BUCDN;  Q9ZER9, TRPE_BUCPS;  
Q44689, TRPE_BUCRM;  Q44691, TRPE_BUCRP;  Q44598, TRPE_BUCSC;  
Q9ZES2, TRPE_BUCTC;  P00896, TRPE_CITFR;  P14953, TRPE_CLOTM;  
P06557, TRPE_CORGL;  P00895, TRPE_ECOLI;  Q9X6J4, TRPE_GEOSE;  
P43761, TRPE_HAEIN;  P33975, TRPE_HALVD;  Q9ZJU5, TRPE_HELPJ;  
O25869, TRPE_HELPY;  Q02001, TRPE_LACLA;  P20463, TRPE_LEPBI;  
Q58475, TRPE_METJA;  O27692, TRPE_METTH;  P26940, TRPE_METTM;  
P67002, TRPE_MYCBO;  Q9X7C5, TRPE_MYCLE;  A0QX93, TRPE_MYCS2;  
P9WFX2, TRPE_MYCTO;  P9WFX3, TRPE_MYCTU;  Q5F8B4, TRPE_NEIG1;  
Q9WW00, TRPE_NEIGO;  Q9XAZ0, TRPE_NEIMA;  P56995, TRPE_NEIMB;  
Q9S358, TRPE_NEIMF;  P20580, TRPE_PSEAE;  P20579, TRPE_PSEPU;  
P21689, TRPE_PSESS;  P15395, TRPE_RHIME;  P95646, TRPE_RHOS4;  
P00898, TRPE_SALTY;  O94582, TRPE_SCHPO;  P00897, TRPE_SERMA;  
P21690, TRPE_SPIAU;  Q9Z4W7, TRPE_STRCO;  Q06128, TRPE_SULSO;  
P20170, TRPE_SYNY3;  Q9YGB3, TRPE_THEKO;  Q08653, TRPE_THEMA;  
P05378, TRPE_THET8;  Q9KST2, TRPE_VIBCH;  P22099, TRPE_VIBPA;  
P00899, TRPE_YEAST;  Q5V214, TRPG1_HALMA;  Q5V632, TRPG2_HALMA;  
P00904, TRPGD_ECOLI;  P00905, TRPGD_SALTY;  Q08654, TRPGD_THEMA;  
P00902, TRPG_ACIAD;  O28670, TRPG_ARCFU;  P18483, TRPG_ASPAW;  
P05328, TRPG_ASPNG;  P26922, TRPG_AZOBR;  Q44696, TRPG_BUCAI;  
P42388, TRPG_BUCAP;  Q89A30, TRPG_BUCBP;  P14952, TRPG_CLOTM;  
Q92411, TRPG_COCHE;  P06558, TRPG_CORGL;  P0CN87, TRPG_CRYNB;  
P27710, TRPG_CRYNH;  P0CN86, TRPG_CRYNJ;  O19914, TRPG_CYACA;  
P48261, TRPG_CYAPA;  P06531, TRPG_EMENI;  P71381, TRPG_HAEIN;  
Q9HPG6, TRPG_HALSA;  P33974, TRPG_HALVD;  Q9ZJU6, TRPG_HELPJ;  
O25868, TRPG_HELPY;  Q02003, TRPG_LACLA;  P20441, TRPG_LEPBI;  
Q57690, TRPG_METJA;  O27693, TRPG_METTH;  P26923, TRPG_METTM;  
P9WN34, TRPG_MYCTO;  P9WN35, TRPG_MYCTU;  P00908, TRPG_NEUCR;  
P24773, TRPG_PENCH;  P25170, TRPG_PHACH;  P20409, TRPG_PHYBL;  
P09575, TRPG_PICAN;  P51362, TRPG_PORPU;  P20576, TRPG_PSEAE;  
P00901, TRPG_PSEPU;  Q1XDC5, TRPG_PYRYE;  Q92370, TRPG_SCHPO;  
P00900, TRPG_SERMA;  P00906, TRPG_SHIDY;  Q06129, TRPG_SULSO;  
Q9YGB2, TRPG_THEKO;  P05379, TRPG_THET8;  Q9KST3, TRPG_VIBCH;  
P22101, TRPG_VIBPA;  P00937, TRPG_YEAST;  Q8ZEG6, TRPG_YERPE;  
P32069, TRPX_ARATH;  P44339, Y1171_HAEIN;  

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