A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.1.1.357
| Accepted Name |
|---|
| 3-alpha-hydroxysteroid 3-dehydrogenase.
|
| Alternative Name(s) |
|---|
| 3-alpha-hydroxysteroid dehydrogenase. |
| Reaction catalysed |
|---|
| A 3-alpha-hydroxysteroid + NAD(P)(+) <=> a 3-oxosteroid + NAD(P)H |
| Comment(s) |
|---|
- The enzyme acts on multiple 3-alpha-hydroxysteroids, such as
androsterone and 5 alpha-dihydrotestosterone.
- The mammalian enzymes are involved in inactivation of steroid
hormones, while the bacterial enzymes are involved in steroid
degradation.
- This entry stands for enzymes whose stereo-specificity with respect
to NAD(+) or NADP(+) is not known (cf. EC 1.1.1.50 and EC 1.1.1.213).
|
| Cross-references |
|---|
| BRENDA | 1.1.1.357 |
| EC2PDB | 1.1.1.357 |
| ExplorEnz | 1.1.1.357 |
| PRIAM enzyme-specific profiles | 1.1.1.357 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.357 |
| IUBMB Enzyme Nomenclature | 1.1.1.357 |
| IntEnz | 1.1.1.357 |
| MEDLINE | Find literature relating to 1.1.1.357 |
| MetaCyc | 1.1.1.357 |
| UniProtKB/Swiss-Prot |
|
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