Home  |  Contact

ENZYME entry: EC 1.1.1.391

Accepted Name
3-beta-hydroxycholanate 3-dehydrogenase (NAD(+)).
Alternative Name(s)
3-beta-hydroxysteroid dehydrogenase.
Reaction catalysed
Isolithocholate + NAD(+) <=> 3-oxo-5-beta-cholan-24-oate + NADH
Comment(s)
  • This bacterial enzyme is involved, along with EC 1.1.1.52 or EC 1.1.1.392, in the modification of secondary bile acids to form 3-beta-bile acids (also known as iso-bile acids).
  • The enzyme catalyzes the reaction in the reduction direction in vivo.
  • Also acts on related 3-oxo bile acids.
  • Cf. 1.1.1.393.
Cross-references
BRENDA1.1.1.391
EC2PDB1.1.1.391
ExplorEnz1.1.1.391
PRIAM enzyme-specific profiles1.1.1.391
KEGG Ligand Database for Enzyme Nomenclature1.1.1.391
IUBMB Enzyme Nomenclature1.1.1.391
IntEnz1.1.1.391
MEDLINEFind literature relating to 1.1.1.391
MetaCyc1.1.1.391
UniProtKB/Swiss-Prot
C8WJW0, 3BHD1_EGGLE;  C8WGQ3, 3BHD2_EGGLE;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-