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ENZYME

ENZYME entry: EC 1.1.1.430

Accepted Name
D-xylose reductase (NADH)
Reaction catalysed
NAD(+) + xylitol <=> D-xylose + H(+) + NADH
Comment(s)
  • Xylose reductases catalyze the reduction of xylose to xylitol, the initial reaction in the fungal D-xylose degradation pathway.
  • Most of the enzymes exhibit a strict requirement for NADPH (cf. EC 1.1.1.431).
  • Some D-xylose reductases have dual cofactor specificity, though they still prefer NADPH to NADH (cf. EC 1.1.1.307).
  • The enzyme from Candida parapsilosis is a rare example of a xylose reductase that significantly prefers NADH, with Km and Vmax values for NADH being 10-fold lower and 10-fold higher, respectively, than for NADPH.
Cross-references
BRENDA1.1.1.430
EC2PDB1.1.1.430
ExplorEnz1.1.1.430
PRIAM enzyme-specific profiles1.1.1.430
KEGG Ligand Database for Enzyme Nomenclature1.1.1.430
IUBMB Enzyme Nomenclature1.1.1.430
IntEnz1.1.1.430
MEDLINEFind literature relating to 1.1.1.430
MetaCyc1.1.1.430
Rhea expert-curated reactions1.1.1.430

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
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