ENZYME entry: EC 1.1.3.43
Accepted Name |
Paromamine 6'-oxidase.
|
Reaction catalysed |
Paromamine + O(2) <=> 6'-dehydroparomamine + H(2)O(2) |
Cofactor(s) |
FAD.
|
Comment(s) |
- Involved in the biosynthetic pathways of several clinically important
aminocyclitol antibiotics, including kanamycin, butirosin, neomycin
and ribostamycin.
- Works in combination with EC 2.6.1.93 to replace the 6-hydroxy group
of paromamine with an amino group.
- The enzyme from the bacterium Streptomyces fradiae also catalyzes
EC 1.1.3.44.
|
Cross-references |
BRENDA | 1.1.3.43 |
EC2PDB | 1.1.3.43 |
ExplorEnz | 1.1.3.43 |
PRIAM enzyme-specific profiles | 1.1.3.43 |
KEGG Ligand Database for Enzyme Nomenclature | 1.1.3.43 |
IUBMB Enzyme Nomenclature | 1.1.3.43 |
IntEnz | 1.1.3.43 |
MEDLINE | Find literature relating to 1.1.3.43 |
MetaCyc | 1.1.3.43 |
Rhea expert-curated reactions | 1.1.3.43 |
UniProtKB/Swiss-Prot |
|
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