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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.1.3.43

Accepted Name
Paromamine 6'-oxidase.
Reaction catalysed
Paromamine + O(2) <=> 6'-dehydroparomamine + H(2)O(2)
Cofactor(s)
FAD.
Comment(s)
  • Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin.
  • Works in combination with EC 2.6.1.93 to replace the 6-hydroxy group of paromamine with an amino group.
  • The enzyme from the bacterium Streptomyces fradiae also catalyzes EC 1.1.3.44.
Cross-references
BRENDA1.1.3.43
EC2PDB1.1.3.43
ExplorEnz1.1.3.43
PRIAM enzyme-specific profiles1.1.3.43
KEGG Ligand Database for Enzyme Nomenclature1.1.3.43
IUBMB Enzyme Nomenclature1.1.3.43
IntEnz1.1.3.43
MEDLINEFind literature relating to 1.1.3.43
MetaCyc1.1.3.43
UniProtKB/Swiss-Prot
Q53U15, NEOG_STRFR

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-