A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.1.3.43
| Accepted Name |
|---|
| Paromamine 6'-oxidase.
|
| Reaction catalysed |
|---|
| Paromamine + O(2) <=> 6'-dehydroparomamine + H(2)O(2) |
| Cofactor(s) |
|---|
| FAD.
|
| Comment(s) |
|---|
- Involved in the biosynthetic pathways of several clinically important
aminocyclitol antibiotics, including kanamycin, butirosin, neomycin
and ribostamycin.
- Works in combination with EC 2.6.1.93 to replace the 6-hydroxy group
of paromamine with an amino group.
- The enzyme from the bacterium Streptomyces fradiae also catalyzes
EC 1.1.3.44.
|
| Cross-references |
|---|
| BRENDA | 1.1.3.43 |
| EC2PDB | 1.1.3.43 |
| ExplorEnz | 1.1.3.43 |
| PRIAM enzyme-specific profiles | 1.1.3.43 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.3.43 |
| IUBMB Enzyme Nomenclature | 1.1.3.43 |
| IntEnz | 1.1.3.43 |
| MEDLINE | Find literature relating to 1.1.3.43 |
| MetaCyc | 1.1.3.43 |
| UniProtKB/Swiss-Prot |
|
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