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ENZYME

ENZYME entry: EC 1.1.3.43

Accepted Name
paromamine 6'-oxidase
Reaction catalysed
O2 + paromamine <=> 6'-oxoparomamine + H2O2
Comment(s)
  • Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin.
  • Works in combination with EC 2.6.1.93 to replace the 6-hydroxy group of paromamine with an amino group.
  • The enzyme from the bacterium Streptomyces fradiae also catalyzes EC 1.1.3.44.
Cross-references
BRENDA1.1.3.43
EC2PDB1.1.3.43
ExplorEnz1.1.3.43
PRIAM enzyme-specific profiles1.1.3.43
KEGG Ligand Database for Enzyme Nomenclature1.1.3.43
IUBMB Enzyme Nomenclature1.1.3.43
IntEnz1.1.3.43
MEDLINEFind literature relating to 1.1.3.43
MetaCyc1.1.3.43
Rhea expert-curated reactions1.1.3.43
UniProtKB/Swiss-Prot
Q53U15, NEOG_STRFR

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