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ENZYME entry: EC 1.1.3.44

Accepted Name
6'''-hydroxyneomycin C oxidase.
Reaction catalysed
6'''-deamino-6'''-hydroxyneomycin C + O(2) <=> 6'''-deamino-6'''-oxoneomycin C + H(2)O(2)
Cofactor(s)
FAD.
Comment(s)
  • Involved in the biosynthetic pathway of aminoglycoside antibiotics of the neomycin family.
  • Works in combination with EC 2.6.1.95 to replace the 6'''-hydroxy group of 6'''-hydroxyneomycin C with an amino group.
  • Also catalyzes EC 1.1.3.43.
Cross-references
BRENDA1.1.3.44
EC2PDB1.1.3.44
ExplorEnz1.1.3.44
PRIAM enzyme-specific profiles1.1.3.44
KEGG Ligand Database for Enzyme Nomenclature1.1.3.44
IUBMB Enzyme Nomenclature1.1.3.44
IntEnz1.1.3.44
MEDLINEFind literature relating to 1.1.3.44
MetaCyc1.1.3.44
Rhea expert-curated reactions1.1.3.44
UniProtKB/Swiss-Prot
Q53U15, NEOG_STRFR

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